Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922248 . T A CCDS33380.1:NM_002181.3:c.484Aag>Tag_NP_002172.2:p.162K>* Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 LYS A:147 B:162 34.0 0.17 G -85.7 -10.1 34.0 0.17 0.0 HOH
 2.839
 NZ
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 LYS A:147 B:162 34.0 0.17 G -85.5 -10.2 34.0 0.17 0.0 HOH
 2.908
 NZ
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 LYS A:147 B:162 33.0 0.165 G -86.8 -9.2 33.0 0.165 0.0 HOH
 2.879
 NZ
 O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 LYS A:147 B:162 34.0 0.17 G -83.7 -14.3 34.0 0.17 0.0 HOH
 3.486
 O
 O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:138 A:162 29.0 0.145 G -94.0 -7.5 29.0 0.145 0.0 HOH
 2.000
 HZ1
 O
LYS B:138 B:162 33.0 0.165 G -88.4 -10.5 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:138 B:162 30.0 0.15 G -92.9 -6.7 30.0 0.15 0.0 HOH
 3.180
 HA
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:138 A:162 35.0 0.175 G -86.4 -21.7 35.0 0.175 0.0 HOH
 3.197
 O
 O
LYS B:138 B:162 33.0 0.165 S -81.9 -20.1 NA NA NA
LYS C:138 C:162 28.0 0.14 G -91.1 -11.8 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:138 B:162 35.0 0.175 G -91.9 -9.3 35.0 0.175 0.0 HOH
 6.758
 CE
 O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 LYS B:137 B:157 27.0 0.135 T -81.0 3.1 27.0 0.135 0.0
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 LYS C:134 C:157 29.0 0.145 -143.3 34.6 29.0 0.145 0.0
LYS F:134 F:157 28.0 0.14 -143.3 34.6 28.0 0.14 0.0
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 LYS C:134 C:157 29.0 0.145 -143.3 34.7 29.0 0.145 0.0
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 LYS C:134 C:157 29.0 0.145 -143.3 34.6 29.0 0.145 0.0
LYS F:134 F:157 28.0 0.14 -143.3 34.6 28.0 0.14 0.0
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 LYS C:134 C:157 31.0 0.155 G -74.6 -27.0 31.0 0.155 0.0
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 LYS B:135 C:157 35.0 0.175 S -76.7 -25.0 35.0 0.175 0.0
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 LYS B:135 C:157 32.0 0.16 S -109.5 5.3 32.0 0.16 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 LYS A:135 A:157 37.0 0.185 G -76.7 -12.1 37.0 0.185 0.0 HOH
 2.700
 NZ
 O
LYS B:135 B:157 37.0 0.185 G -80.2 -3.6 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 LYS C:129 H:157 45.0 0.225 G -96.4 -15.3 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 LYS A:129 A:157 33.0 0.165 G -84.6 -9.0 33.0 0.165 0.0 HOH
 3.386
 C
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 LYS A:129 A:157 32.0 0.16 G -88.3 -11.6 32.0 0.16 0.0 GOL
HOH
 2.499
2.046
 HA
HZ3
 H12
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 LYS B:245 B:157 22.0 0.11 G -99.8 -9.5 22.0 0.11 0.0
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 LYS A:125 A:158 33.0 0.165 G -90.1 -12.2 33.0 0.165 0.0 HOH
 2.863
 HZ2
 O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 LYS A:137 A:158 32.0 0.16 G -95.0 -9.9 32.0 0.16 0.0 HOH
 3.453
 C
 O
LYS B:137 B:158 31.0 0.155 G -87.6 -12.2 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 LYS B:133 H:158 49.0 0.245 G -80.7 -19.3 49.0 0.245 0.0
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 LYS A:121 A:158 31.0 0.155 G -89.4 -13.0 31.0 0.155 0.0 HOH
 3.412
 C
 O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 LYS A:121 A:158 31.0 0.155 G -84.7 -12.2 31.0 0.155 0.0 HOH
 3.439
 C
 O
LYS B:121 B:158 32.0 0.16 G -84.1 -12.3 32.0 0.16 0.0 HOH
 3.068
 NZ
 O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 LYS A:123 A:158 35.0 0.175 T -85.4 -11.0 35.0 0.175 0.0 HOH
 3.852
 N
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 LYS A:119 A:158 37.0 0.185 T -70.5 -25.0 37.0 0.185 0.0
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 LYS A:119 A:158 29.0 0.145 G -107.8 -5.4 29.0 0.145 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 LYS A:162 A:162 36.0 0.18 G -80.0 -18.8