Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922253 . C A CCDS33380.1:NM_002181.3:c.479cGc>cTc_NP_002172.2:p.160R>L Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 ARG A:145 B:160 132.0 0.587 G -59.0 -22.8 132.0 0.587 0.0 HOH
 2.610
 NE
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:145 B:160 131.0 0.582 G -59.9 -20.3 131.0 0.582 0.0 HOH
 2.765
 O
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:145 B:160 139.0 0.618 G -60.4 -21.6 139.0 0.618 0.0 SO4
HOH
 6.538
2.779
 NH1
O
 O2
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 ARG A:145 B:160 129.0 0.573 G -62.0 -21.6 129.0 0.573 0.0 SO4
HOH
 8.980
2.709
 NH1
O
 O1
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:136 A:160 137.0 0.609 G -55.4 -24.8 75.0 0.333 0.276 D:Q4KMG0:0.276
 HOH
 1.896
 HH22
 O
ARG B:136 B:160 126.0 0.56 G -59.7 -23.0 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:136 B:160 140.0 0.622 G -64.4 -20.2 81.0 0.36 0.262 B:Q9BWV1:0.262
 HOH
 2.005
 HE
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:136 A:160 136.0 0.604 G -51.3 -23.8 136.0 0.604 0.0 HOH
 3.020
 NE
 O
ARG B:136 B:160 134.0 0.596 T -61.0 -14.5 NA NA NA
ARG C:136 C:160 125.0 0.556 G -52.3 -21.4 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:136 B:160 134.0 0.596 G -57.1 -21.9 79.0 0.351 0.245 B:Q9BWV1:0.244
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 ARG B:135 B:155 147.0 0.653 S -80.9 -13.7 62.0 0.276 0.377 A:Q13635:0.378
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:132 C:155 146.0 0.649 S -150.0 178.9 41.0 0.182 0.467 A:Q13635:0.467
ARG F:132 F:155 147.0 0.653 S -150.1 178.9 41.0 0.182 0.471 D:Q13635:0.471
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:132 C:155 152.0 0.676 S -150.1 178.9 42.0 0.187 0.489 A:Q13635:0.489
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:132 C:155 146.0 0.649 S -150.0 178.9 41.0 0.182 0.467 A:Q13635:0.467
ARG F:132 F:155 147.0 0.653 S -150.1 178.9 41.0 0.182 0.471 D:Q13635:0.471
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 ARG C:132 C:155 158.0 0.702 G -58.4 -37.4 57.0 0.253 0.449 B:Q13635:0.449
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 ARG B:133 C:155 172.0 0.764 T -72.9 153.9 100.0 0.444 0.32 C:Q13635:0.32
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 ARG B:133 C:155 116.0 0.516 T -94.9 152.4 116.0 0.516 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 ARG A:133 A:155 137.0 0.609 G -64.4 -22.0 137.0 0.609 0.0 SO4
HOH
 9.104
2.802
 NH2
NH1
 O2
O
ARG B:133 B:155 138.0 0.613 G -64.4 -22.1 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 ARG C:127 H:155 144.0 0.64 G -61.9 -26.3 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 ARG A:127 A:155 143.0 0.636 G -55.8 -29.1 54.0 0.24 0.396 C:None:0.396
 HOH
 2.831
 NH1
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 ARG A:127 A:155 138.0 0.613 G -61.4 -23.9 138.0 0.613 0.0 GOL
HOH
 6.532
2.126
 O
HH21
 H12
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 ARG B:243 B:155 153.0 0.68 G -69.8 -34.1 74.0 0.329 0.351 A:Q13635+U6GSR1:0.351
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 ARG A:123 A:156 106.0 0.471 G -58.2 -20.1 106.0 0.471 0.0 SO4
HOH
 2.411
1.994
 HH21
O
 O2
H1
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 ARG A:135 A:156 135.0 0.6 G -69.5 -18.6 81.0 0.36 0.24 D:Q4KMG0:0.24
 HOH
 2.692
 O
 O
ARG B:135 B:156 141.0 0.627 G -55.4 -27.9 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 ARG B:131 H:156 126.0 0.56 G -54.1 -28.2 126.0 0.56 0.0 SO4
 6.024
 NH2
 O4
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:119 A:156 146.0 0.649 G -60.8 -22.4 146.0 0.649 0.0 ASG
BDP
ACT
HOH
 9.133
9.625
6.475
2.692
 NH2
NH2
NH2
NE
 OSB
O2
CH3
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:119 A:156 119.0 0.529 G -60.9 -23.2 119.0 0.529 0.0 IDS
SGN
IDS
SGN
IDS
HOH
 8.548
3.137
4.255
4.510
5.972
5.054
 NH1
NH1
NH1
NH2
NH2
O
 O4
O5S
O1S
C3
O2S
O
ARG B:119 B:156 136.0 0.604 G -61.3 -23.2 136.0 0.604 0.0 SGN
IDS
SGN
IDS
SGN
IDS
HOH
 9.993
5.731
3.627
4.058
8.794
9.260
9.454
 NH2
NH2
NH2
NH1
NH1
NH1
N
 O4
O4
C2
O6A
O6
O3S
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 ARG A:121 A:156 147.0 0.653 T -53.8 -13.8 147.0 0.653 0.0 HOH
 2.952
 O
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 ARG A:117 A:156 134.0 0.596 T -56.3 -22.5 99.0 0.44 0.156 B:Q96QV1:0.156
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 ARG A:117 A:156 119.0 0.529 G -65.4 -13.0 83.0 0.369 0.16 B:Q96QV1:0.16

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 ARG A:160 A:160 158.0 0.702 G -61.4 -23.5