Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922260 . G A CCDS33380.1:NM_002181.3:c.472Cgc>Tgc_NP_002172.2:p.158R>C Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 ARG A:143 B:158 141.0 0.627 54.3 34.9 141.0 0.627 0.0 HOH
 2.693
 O
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:143 B:158 141.0 0.627 55.0 33.3 141.0 0.627 0.0 HOH
 2.635
 O
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:143 B:158 146.0 0.649 55.2 31.1 146.0 0.649 0.0 SO4
HOH
 3.003
3.396
 NE
O
 O1
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 ARG A:143 B:158 139.0 0.618 50.8 36.9 139.0 0.618 0.0 SO4
SO4
HOH
 3.440
9.980
2.772
 CD
NE
O
 O1
O4
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:134 A:158 133.0 0.591 49.6 33.2 62.0 0.276 0.315 D:Q4KMG0:0.316
 HOH
 1.987
 HH12
 O
ARG B:134 B:158 123.0 0.547 53.8 33.6 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:134 B:158 130.0 0.578 55.1 31.4 62.0 0.276 0.302 B:Q9BWV1:0.302
 HOH
 2.097
 HH12
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:134 A:158 161.0 0.716 49.5 43.0 161.0 0.716 0.0 HOH
 2.751
 O
 O
ARG B:134 B:158 161.0 0.716 58.6 27.6 NA NA NA
ARG C:134 C:158 144.0 0.64 50.9 30.8 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:134 B:158 136.0 0.604 63.2 22.4 66.0 0.293 0.311 B:Q9BWV1:0.311
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 ARG B:133 B:153 155.0 0.689 59.4 29.1 39.0 0.173 0.516 A:Q13635:0.516
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:130 C:153 139.0 0.618 -71.5 143.7 133.0 0.591 0.027 A:Q13635:0.027
ARG F:130 F:153 144.0 0.64 -71.5 143.7 138.0 0.613 0.027 D:Q13635:0.027
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:130 C:153 144.0 0.64 -71.5 143.7 138.0 0.613 0.027 A:Q13635:0.027
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:130 C:153 139.0 0.618 -71.5 143.7 133.0 0.591 0.027 A:Q13635:0.027
ARG F:130 F:153 144.0 0.64 -71.5 143.7 138.0 0.613 0.027 D:Q13635:0.027
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 ARG C:130 C:153 153.0 0.68 53.7 31.7 19.0 0.084 0.596 B:Q13635:0.596
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 ARG B:131 C:153 147.0 0.653 45.2 40.3 16.0 0.071 0.582 C:Q13635:0.582
 CA
 9.947
 NH2
 CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 ARG B:131 C:153 117.0 0.52 31.9 50.1 117.0 0.52 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 ARG A:131 A:153 150.0 0.667 55.8 26.2 150.0 0.667 0.0 SO4
HOH
 2.781
2.974
 NH1
NE
 O2
O
ARG B:131 B:153 152.0 0.676 64.7 23.9 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 ARG C:125 H:153 151.0 0.671 66.2 44.7 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 ARG A:125 A:153 146.0 0.649 51.2 36.6 17.0 0.076 0.573 C:None:0.573
 HOH
 2.628
 O
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 ARG A:125 A:153 164.0 0.729 54.0 31.8 164.0 0.729 0.0 CL
HOH
 3.996
2.818
 HH11
HH11
 CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 ARG B:241 B:153 147.0 0.653 58.0 64.7 32.0 0.142 0.511 A:Q13635+U6GSR1:0.511
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 ARG A:121 A:154 134.0 0.596 50.3 33.6 134.0 0.596 0.0 SO4
HOH
 1.867
1.802
 HE
HH11
 O1
O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 ARG A:133 A:154 134.0 0.596 54.0 28.7 65.0 0.289 0.307 D:Q4KMG0:0.307
 HOH
 2.735
 O
 O
ARG B:133 B:154 136.0 0.604 52.1 29.2 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 ARG B:129 H:154 139.0 0.618 58.4 29.0 111.0 0.493 0.125 A:Q3TDN0:0.124
 SO4
 2.947
 NE
 O3
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:117 A:154 152.0 0.676 53.8 34.6 152.0 0.676 0.0 ASG
BDP
ACT
HOH
 3.364
7.093
3.770
2.845
 NH1
NH1
CG
O
 O4
C1
O
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:117 A:154 120.0 0.533 66.6 24.5 120.0 0.533 0.0 SGN
IDS
SGN
IDS
SGN
HOH
 8.864
6.537
3.167
3.059
4.490
9.028
 O
NH2
NH2
NE
CD
C
 O5S
O4
O3
O6B
C1
O
ARG B:117 B:154 157.0 0.698 66.6 23.2 157.0 0.698 0.0 SGN
IDS
SGN
HOH
 3.174
4.111
4.887
3.774
 NH2
CD
CD
NH2
 O1S
O6A
O4S
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 ARG A:119 A:154 158.0 0.702 60.5 26.2 158.0 0.702 0.0 HOH
 4.507
 CB
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 ARG A:115 A:154 150.0 0.667 60.5 24.2 99.0 0.44 0.227 B:Q96QV1:0.227
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 ARG A:115 A:154 149.0 0.662 63.2 -3.7 102.0 0.453 0.209 B:Q96QV1:0.209

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 ARG A:158 A:158 157.0 0.698 56.2 28.1