Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922284 . C A CCDS33380.1:NM_002181.3:c.448Gcg>Tcg_NP_002172.2:p.150A>S Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 ALA A:135 B:150 1.0 0.009 E -142.0 140.5 1.0 0.009 0.0 ZN
HOH
 5.003
2.833
 CB
O
 ZN
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ALA A:135 B:150 1.0 0.009 E -141.4 138.8 1.0 0.009 0.0 ZN
HOH
 4.959
2.782
 CB
O
 ZN
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ALA A:135 B:150 1.0 0.009 E -141.0 140.5 1.0 0.009 0.0 ZN
HOH
 4.999
2.752
 CB
O
 ZN
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 ALA A:135 B:150 1.0 0.009 E -147.6 148.0 1.0 0.009 0.0 ZN
CO3
HOH
 4.991
6.105
4.848
 CB
CB
CB
 ZN
O2
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ALA A:126 A:150 0.0 0.0 E -142.2 149.7 0.0 0.0 0.0 ZN
CA
CA
HOH
 4.099
9.577
9.315
4.515
 HB1
O
O
HB2
 ZN
CA
CA
O
ALA B:126 B:150 0.0 0.0 E -142.1 152.6 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ALA A:126 B:150 0.0 0.0 E -143.8 152.8 0.0 0.0 0.0 ZN
CA
CA
HOH
 4.052
9.597
9.378
2.194
 HB1
O
O
H
 ZN
CA
CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ALA A:126 A:150 1.0 0.009 E -138.2 150.0 1.0 0.009 0.0 ZN
HOH
 5.120
2.905
 CB
O
 ZN
O
ALA B:126 B:150 1.0 0.009 E -136.3 141.4 NA NA NA
ALA C:126 C:150 1.0 0.009 E -146.9 148.3 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ALA A:126 B:150 0.0 0.0 E -139.3 156.6 0.0 0.0 0.0 ZN
CA
CA
HOH
 5.857
9.723
9.513
7.953
 CB
O
O
O
 ZN
CA
CA
O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 ALA B:125 B:145 0.0 0.0 E -147.8 130.7 0.0 0.0 0.0 ZN
CA
CA
 6.330
9.053
8.867
 CB
O
O
 ZN
CA
CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 ALA C:122 C:145 1.0 0.009 E -152.6 143.2 1.0 0.009 0.0 ZN
CA
CA
 5.608
9.316
9.091
 CB
O
O
 ZN
CA
CA
ALA F:122 F:145 2.0 0.017 E -152.6 143.2 2.0 0.017 0.0 ZN
CA
CA
 5.608
9.317
9.092
 CB
O
O
 ZN
CA
CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 ALA C:122 C:145 2.0 0.017 E -152.5 143.2 2.0 0.017 0.0 ZN
CA
CA
 5.609
9.316
9.092
 CB
O
O
 ZN
CA
CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 ALA C:122 C:145 1.0 0.009 E -152.6 143.2 1.0 0.009 0.0 ZN
CA
CA
 5.608
9.316
9.091
 CB
O
O
 ZN
CA
CA
ALA F:122 F:145 2.0 0.017 E -152.6 143.2 2.0 0.017 0.0 ZN
CA
CA
 5.608
9.317
9.092
 CB
O
O
 ZN
CA
CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 ALA C:122 C:145 1.0 0.009 E -136.7 149.0 1.0 0.009 0.0 ZN
CA
CA
 5.701
9.260
9.619
 CB
O
O
 ZN
CA
CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 ALA B:123 C:145 0.0 0.0 -81.0 162.2 0.0 0.0 0.0 ZN
CA
 6.281
9.847
 CB
O
 ZN
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 ALA B:123 C:145 0.0 0.0 -79.9 140.3 0.0 0.0 0.0 ZN
 6.861
 CB
 ZN
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 ALA A:123 A:145 1.0 0.009 E -143.8 137.7 1.0 0.009 0.0 ZN
HOH
 5.066
4.661
 CB
CB
 ZN
O
ALA B:123 B:145 1.0 0.009 E -145.1 139.0 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 ALA C:117 H:145 0.0 0.0 E -115.6 152.7 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 ALA A:117 A:145 0.0 0.0 E -142.1 149.4 0.0 0.0 0.0 ZN
CA
CA
SO4
HOH
 4.763
9.781
9.345
5.424
4.941
 CB
O
O
CB
CB
 ZN
CA
CA
O4
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 ALA A:117 A:145 2.0 0.017 E -140.2 143.3 2.0 0.017 0.0 DMS
MG
ZN
MG
HOH
 6.023
9.332
4.809
4.821
2.722
 HB1
O
HB1
HB1
H
 H22
MG
ZN
MG
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 ALA B:233 B:145 0.0 0.0 E -161.7 157.7 0.0 0.0 0.0 ZN
 4.889
 HB1
 ZN
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 ALA A:113 A:146 1.0 0.009 E -148.4 146.0 1.0 0.009 0.0 ZN
HOH
 4.951
1.867
 CB
O
 ZN
H1
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 ALA A:125 A:146 1.0 0.009 E -139.0 148.0 1.0 0.009 0.0 ZN
CA
CA
HOH
 5.404
9.512
9.297
2.694
 CB
O
O
O
 ZN
CA
CA
O
ALA B:125 B:146 0.0 0.0 E -142.4 151.0 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 ALA B:121 H:146 0.0 0.0 E -141.7 154.8 0.0 0.0 0.0 CA
CA
ZN
 9.738
9.669
5.170
 O
O
CB
 CA
CA
ZN
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ALA A:109 A:146 1.0 0.009 E -138.1 148.7 1.0 0.009 0.0 ZN
CA
CA
HOH
 4.884
9.486
9.761
4.766
 CB
O
O
CB
 ZN
CA
CA
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ALA A:109 A:146 0.0 0.0 E -145.4 147.7 0.0 0.0 0.0 ZN
CA
CA
HOH
 5.197
9.489
9.743
5.075
 CB
O
O
CB
 ZN
CA
CA
O
ALA B:109 B:146 0.0 0.0 E -145.7 149.1 0.0 0.0 0.0 ZN
CA
CA
HOH
 5.106
9.851
9.640
6.945
 CB
O
O
CB
 ZN
CA
CA
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 ALA A:111 A:146 1.0 0.009 E -142.5 145.0 1.0 0.009 0.0 ZN
CA
HOH
 5.132
9.878
2.621
 CB
O
O
 ZN
CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 ALA A:107 A:146 1.0 0.009 E -127.7 150.6 1.0 0.009 0.0 ZN
 4.925
 CB
 ZN
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 ALA A:107 A:146 1.0 0.009 E -120.4 149.0 1.0 0.009 0.0 ZN
CA
CA
 5.082
9.688
9.965
 CB
O
O
 ZN
CA
CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 ALA A:150 A:150 0.0 0.0 E -125.0 156.2