Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922341 . C A CCDS33380.1:NM_002181.3:c.391Gag>Tag_NP_002172.2:p.131E>* Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 GLU A:116 B:131 15.0 0.079 E -160.3 119.5 15.0 0.079 0.0 ZN
HOH
 5.467
2.777
 CG
OE1
 ZN
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 LYS A:116 B:131 16.0 0.08 E -161.1 127.2 16.0 0.08 0.0 ZN
HOH
 5.611
2.734
 O
NZ
 ZN
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLU A:116 B:131 19.0 0.1 E -160.1 133.7 19.0 0.1 0.0 ZN
SO4
HOH
 5.438
7.107
2.710
 CG
N
OE2
 ZN
O3
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 GLU A:116 B:131 38.0 0.2 E -162.0 134.9 38.0 0.2 0.0 ZN
SO4
CO3
HOH
 5.555
4.926
7.076
2.911
 CG
OE1
CG
OE1
 ZN
O1
O2
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:107 A:131 6.0 0.032 E -139.2 133.0 0.0 0.0 0.032 D:Q4KMG0:0.032
 ZN
CA
CA
HOH
 4.969
2.317
2.571
2.638
 HB2
OE2
OE1
HG3
 ZN
CA
CA
O
GLU B:107 B:131 6.0 0.032 E -141.0 131.1 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:107 B:131 7.0 0.037 E -145.4 129.1 0.0 0.0 0.037 B:Q9BWV1:0.037
 ZN
CA
CA
HOH
 5.073
2.333
2.491
2.489
 HB2
OE2
OE1
HG3
 ZN
CA
CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:107 A:131 19.0 0.1 E -168.0 136.4 19.0 0.1 0.0 ZN
HOH
 5.630
4.545
 CG
OE2
 ZN
O
GLU B:107 B:131 27.0 0.142 E -170.6 122.5 NA NA NA
GLU C:107 C:131 25.0 0.132 E -142.9 136.5 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:107 B:131 11.0 0.058 E -154.4 125.3 1.0 0.005 0.053 B:Q9BWV1:0.053
 ZN
CA
CA
HOH
 5.870
2.973
2.822
2.872
 CB
OE2
OE2
OE2
 ZN
CA
CA
O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 GLU B:106 B:126 51.0 0.268 E -133.4 123.7 13.0 0.068 0.2 A:Q13635:0.2
 ZN
CA
CA
 4.706
4.939
2.966
 OE1
CG
CG
 ZN
CA
CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:103 C:126 50.0 0.263 E -133.4 123.7 11.0 0.058 0.205 A:Q13635:0.205
 ZN
CA
CA
 5.578
4.940
2.966
 OE1
CG
CG
 ZN
CA
CA
GLU F:103 F:126 49.0 0.258 E -133.5 123.8 9.0 0.047 0.211 D:Q13635:0.211
 ZN
CA
CA
 5.578
4.940
2.966
 OE1
CG
CG
 ZN
CA
CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:103 C:126 48.0 0.253 E -133.5 123.7 9.0 0.047 0.206 A:Q13635:0.205
 ZN
CA
CA
 5.578
4.940
2.966
 OE1
CG
CG
 ZN
CA
CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:103 C:126 50.0 0.263 E -133.4 123.7 11.0 0.058 0.205 A:Q13635:0.205
 ZN
CA
CA
 5.578
4.940
2.966
 OE1
CG
CG
 ZN
CA
CA
GLU F:103 F:126 49.0 0.258 E -133.5 123.8 9.0 0.047 0.211 D:Q13635:0.211
 ZN
CA
CA
 5.578
4.940
2.966
 OE1
CG
CG
 ZN
CA
CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 GLU C:103 C:126 17.0 0.089 E -144.4 132.5 16.0 0.084 0.005 B:Q13635:0.005
 ZN
CA
CA
 6.083
2.335
2.174
 CB
OE1
OE2
 ZN
CA
CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 GLU B:104 C:126 34.0 0.179 -136.8 98.4 1.0 0.005 0.174 C:Q13635:0.174
 ZN
CA
CA
 5.104
3.357
3.603
 OE1
CG
CG
 ZN
CA
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 GLU B:104 C:126 29.0 0.153 -125.6 90.4 29.0 0.153 0.0 ZN
 7.921
 O
 ZN
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 GLU A:104 A:126 45.0 0.237 E -164.8 139.8 45.0 0.237 0.0 ZN
SO4
HOH
 5.894
8.742
3.496
 O
N
CG
 ZN
O1
O
GLU B:104 B:126 21.0 0.111 E -153.2 127.0 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 GLU C:98 H:126 13.0 0.068 E -137.6 144.6 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 GLU A:98 A:126 14.0 0.074 E -145.0 132.8 6.0 0.032 0.042 C:None:0.042
 ZN
CA
CA
SO4
HOH
 5.730
2.361
2.353
7.496
2.946
 CB
OE2
OE1
CB
OE2
 ZN
CA
CA
O3
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 GLU A:98 A:126 16.0 0.084 E -155.5 139.6 16.0 0.084 0.0 DMS
MG
ZN
MG
CL
HOH
 8.983
2.034
4.864
4.871
9.435
2.636
 HG2
OE1
HG2
HG2
N
OE2
 H21
MG
ZN
MG
CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 GLU B:214 B:126 21.0 0.111 E -159.3 121.6 12.0 0.063 0.048 A:Q13635+U6GSR1:0.047
 ZN
 5.715
 HB3
 ZN
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 GLU A:94 A:127 19.0 0.1 E -157.1 131.2 19.0 0.1 0.0 ZN
SO4
HOH
 5.632
7.202
2.001
 CG
N
OE1
 ZN
O3
H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 GLU A:106 A:127 6.0 0.032 E -139.6 129.3 0.0 0.0 0.032 D:Q4KMG0:0.032
 ZN
CA
CA
HOH
 5.962
2.369
2.593
2.952
 CB
OE2
OE1
OE2
 ZN
CA
CA
O
GLU B:106 B:127 7.0 0.037 E -136.9 129.8 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 GLU B:102 H:127 3.0 0.016 E -137.6 132.8 3.0 0.016 0.0 CA
CA
ZN
SO4
 2.300
2.326
5.690
7.487
 OE2
OE1
CB
N
 CA
CA
ZN
O1
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLU A:90 A:127 17.0 0.089 E -144.7 132.2 17.0 0.089 0.0 ZN
CA
CA
ACT
HOH
 5.671
2.519
2.310
8.432
3.052
 CB
OE1
OE2
N
OE2
 ZN
CA
CA
CH3
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLU A:90 A:127 12.0 0.063 E -150.3 131.3 12.0 0.063 0.0 IDS
SGN
ZN
CA
CA
HOH
 7.497
9.150
5.720
2.421
2.322
3.322
 CG
N
CB
OE1
OE2
OE2
 O1S
O1S
ZN
CA
CA
O
GLU B:90 B:127 15.0 0.079 E -150.0 131.3 15.0 0.079 0.0 SGN
SGN
IDS
ZN
CA
CA
HOH
 9.738
7.143
8.503
5.719
2.307
2.471
3.016
 N
N
CG
CB
OE2
OE1
OE2
 O1S
O5S
O1S
ZN
CA
CA
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 GLU A:92 A:127 11.0 0.058 E -141.5 126.5 11.0 0.058 0.0 ZN
CA
HOH
 5.575
4.283
2.519
 CG
OE1
OE1
 ZN
CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 GLU A:88 A:127 52.0 0.274 E -156.3 138.0 30.0 0.158 0.116 B:Q96QV1:0.116
 ZN
 5.986
 O
 ZN
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 GLU A:88 A:127 9.0 0.047 E -142.6 139.3 0.0 0.0 0.047 B:Q96QV1:0.047
 ZN
CA
CA
 5.954
2.404
2.290
 CB
OE1
OE2
 ZN
CA
CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 GLU A:131 A:131 31.0 0.163 E -152.1 130.6