Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922343 . G A CCDS33380.1:NM_002181.3:c.389aCc>aTc_NP_002172.2:p.130T>I Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 THR A:115 B:130 24.0 0.171 E -98.7 -16.3 24.0 0.171 0.0 ZN
SO4
HOH
 7.811
9.326
2.883
 OG1
N
O
 ZN
O1
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 THR A:115 B:130 23.0 0.164 E -95.3 -17.5 23.0 0.164 0.0 ZN
HOH
 7.716
2.871
 OG1
O
 ZN
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 THR A:115 B:130 25.0 0.179 E -104.7 -11.8 25.0 0.179 0.0 ZN
SO4
HOH
 7.694
3.485
2.847
 OG1
CG2
O
 ZN
O3
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 THR A:115 B:130 28.0 0.2 E -108.9 -8.9 28.0 0.2 0.0 ZN
SO4
SO4
HOH
 7.808
6.471
4.251
2.765
 OG1
CG2
O
O
 ZN
O3
O1
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:106 A:130 22.0 0.157 E -86.0 -36.8 6.0 0.043 0.114 D:Q4KMG0:0.114
 ZN
CA
CA
HOH
 7.166
2.364
5.536
2.651
 HG1
O
O
OG1
 ZN
CA
CA
O
THR B:106 B:130 22.0 0.157 E -86.8 -33.3 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:106 B:130 22.0 0.157 E -91.2 -30.3 7.0 0.05 0.107 B:Q9BWV1:0.107
 ZN
CA
CA
HOH
 7.030
2.375
5.534
2.052
 HG1
O
O
HG1
 ZN
CA
CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:106 A:130 16.0 0.114 E -94.1 -17.2 16.0 0.114 0.0 ZN
HOH
 7.236
3.879
 OG1
CG2
 ZN
O
THR B:106 B:130 19.0 0.136 E -91.2 -7.7 NA NA NA
THR C:106 C:130 18.0 0.129 E -89.4 -29.2 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 THR A:106 B:130 18.0 0.129 E -103.7 -20.8 5.0 0.036 0.093 B:Q9BWV1:0.093
 ZN
CA
CA
HOH
 7.329
2.668
5.738
5.519
 OG1
O
O
O
 ZN
CA
CA
O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 THR B:105 B:125 11.0 0.079 E -83.9 -50.3 4.0 0.029 0.05 A:Q13635:0.05
 ZN
CA
CA
 6.722
6.445
2.497
 OG1
O
O
 ZN
CA
CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 THR C:102 C:125 11.0 0.079 E -84.0 -50.3 3.0 0.021 0.058 A:Q13635:0.057
 ZN
CA
CA
 7.557
6.445
2.497
 OG1
O
O
 ZN
CA
CA
THR F:102 F:125 10.0 0.071 E -83.9 -50.3 2.0 0.014 0.057 D:Q13635:0.057
 ZN
CA
CA
 7.557
6.445
2.496
 OG1
O
O
 ZN
CA
CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 THR C:102 C:125 11.0 0.079 E -83.9 -50.3 2.0 0.014 0.065 A:Q13635:0.064
 ZN
CA
CA
 7.558
6.445
2.497
 OG1
O
O
 ZN
CA
CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 THR C:102 C:125 11.0 0.079 E -84.0 -50.3 3.0 0.021 0.058 A:Q13635:0.057
 ZN
CA
CA
 7.557
6.445
2.497
 OG1
O
O
 ZN
CA
CA
THR F:102 F:125 10.0 0.071 E -83.9 -50.3 2.0 0.014 0.057 D:Q13635:0.057
 ZN
CA
CA
 7.557
6.445
2.496
 OG1
O
O
 ZN
CA
CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 THR C:102 C:125 17.0 0.121 E -95.7 -27.1 4.0 0.029 0.092 B:Q13635:0.093
 ZN
CA
CA
 7.335
5.772
2.545
 OG1
O
O
 ZN
CA
CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 THR B:103 C:125 15.0 0.107 S -92.8 -46.4 1.0 0.007 0.1 C:Q13635:0.1
 ZN
CA
CA
 7.084
1.962
3.630
 OG1
O
O
 ZN
CA
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 THR B:103 C:125 3.0 0.021 S -111.6 -46.7 3.0 0.021 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 THR A:103 A:125 24.0 0.171 E -95.9 -17.7 24.0 0.171 0.0 ZN
SO4
HOH
 7.511
5.966
2.537
 OG1
CG2
OG1
 ZN
O1
O
THR B:103 B:125 23.0 0.164 E -100.4 -20.1 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 THR C:97 H:125 22.0 0.157 E -103.8 -36.0 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 THR A:97 A:125 19.0 0.136 E -93.5 -28.7 4.0 0.029 0.107 C:None:0.107
 ZN
CA
CA
SO4
HOH
 7.259
2.372
5.515
9.577
2.695
 OG1
O
O
OG1
OG1
 ZN
CA
CA
O3
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 THR A:97 A:125 24.0 0.171 E -103.3 -17.2 24.0 0.171 0.0 MG
ZN
MG
CL
HOH
 4.709
7.626
7.625
5.501
2.244
 O
OG1
OG1
HG22
O
 MG
ZN
MG
CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 THR B:213 B:125 28.0 0.2 E -77.1 -46.8 3.0 0.021 0.179 A:Q13635+U6GSR1:0.179
 ZN
 7.412
 HB
 ZN
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 THR A:93 A:126 19.0 0.136 E -99.6 -19.3 19.0 0.136 0.0 ZN
SO4
HOH
 7.744
3.596
2.273
 OG1
CG2
OG1
 ZN
O3
H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 THR A:105 A:126 21.0 0.15 E -93.6 -34.7 6.0 0.043 0.107 D:Q4KMG0:0.107
 ZN
CA
CA
HOH
 7.249
2.359
5.596
2.635
 OG1
O
O
OG1
 ZN
CA
CA
O
THR B:105 B:126 24.0 0.171 E -90.6 -34.6 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 THR B:101 H:126 21.0 0.15 E -112.9 -21.1 21.0 0.15 0.0 CA
CA
ZN
SO4
 2.583
5.132
7.719
3.906
 O
O
OG1
CG2
 CA
CA
ZN
O1
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 THR A:89 A:126 20.0 0.143 E -98.9 -26.9 20.0 0.143 0.0 ASG
ZN
CA
CA
ACT
HOH
 6.995
7.422
5.705
2.411
4.246
4.382
 CG2
OG1
O
O
CG2
OG1
 OSC
ZN
CA
CA
C
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 THR A:89 A:126 17.0 0.121 E -97.4 -23.2 17.0 0.121 0.0 SGN
IDS
SGN
ZN
CA
CA
HOH
 8.038
4.720
6.270
7.423
5.721
2.234
5.732
 CG2
CG2
CG2
OG1
O
O
O
 O4
O2S
O1S
ZN
CA
CA
O
THR B:89 B:126 19.0 0.136 E -100.3 -22.3 19.0 0.136 0.0 SGN
IDS
SGN
IDS
ZN
CA
CA
HOH
 6.237
6.572
3.576
8.420
7.466
2.406
5.778
5.492
 CG2
CG2
CG2
CB
OG1
O
O
O
 O1S
O6A
O5S
O3S
ZN
CA
CA
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 THR A:91 A:126 21.0 0.15 E -94.0 -32.4 21.0 0.15 0.0 ZN
CA
HOH
 7.498
2.827
3.860
 OG1
O
O
 ZN
CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 THR A:87 A:126 28.0 0.2 E -97.4 -25.7 1.0 0.007 0.193 B:Q96QV1:0.193
 ZN
 7.486
 OG1
 ZN
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 THR A:87 A:126 22.0 0.157 E -94.3 -35.1 0.0 0.0 0.157 B:Q96QV1:0.157
 ZN
CA
CA
 7.440
2.387
6.210
 OG1
O
O
 ZN
CA
CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 THR A:130 A:130 22.0 0.157 E -93.3 -28.7