Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922349 . C A CCDS33380.1:NM_002181.3:c.383cGg>cTg_NP_002172.2:p.128R>L Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 ARG A:113 B:128 30.0 0.133 E -131.3 136.2 30.0 0.133 0.0 SO4
HOH
 7.207
2.997
 CG
NH2
 O1
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:113 B:128 29.0 0.129 E -133.8 133.7 29.0 0.129 0.0 HOH
 2.879
 NH2
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ARG A:113 B:128 33.0 0.147 E -130.8 133.0 33.0 0.147 0.0 SO4
HOH
 2.844
2.926
 NH1
NH2
 O1
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 ARG A:113 B:128 27.0 0.12 E -136.6 133.3 27.0 0.12 0.0 SO4
SO4
HOH
 2.890
7.546
2.945
 NH2
NH2
NE
 O3
O4
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:104 A:128 21.0 0.093 E -126.1 132.7 0.0 0.0 0.093 D:Q4KMG0:0.093
 CA
HOH
 8.285
1.995
 HH21
HH12
 CA
O
ARG B:104 B:128 19.0 0.084 E -124.6 132.2 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:104 B:128 22.0 0.098 E -127.0 134.5 0.0 0.0 0.098 B:Q9BWV1:0.098
 CA
HOH
 8.152
1.975
 HH21
HH12
 CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:104 A:128 28.0 0.124 E -128.9 137.1 28.0 0.124 0.0 HOH
 3.181
 NH1
 O
ARG B:104 B:128 33.0 0.147 E -124.1 138.6 NA NA NA
ARG C:104 C:128 33.0 0.147 E -126.0 131.5 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ARG A:104 B:128 26.0 0.116 E -122.4 134.9 1.0 0.004 0.112 B:Q9BWV1:0.111
 CA
 8.318
 NH2
 CA
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 ARG B:103 B:123 25.0 0.111 E -99.7 108.7 3.0 0.013 0.098 A:Q13635:0.098
 CA
 8.257
 NH2
 CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:100 C:123 53.0 0.236 E -115.3 100.6 6.0 0.027 0.209 A:Q13635:0.209
 CA
 8.285
 NH1
 CA
ARG F:100 F:123 53.0 0.236 E -115.3 100.7 5.0 0.022 0.214 D:Q13635:0.213
 CA
 8.284
 NH1
 CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:100 C:123 51.0 0.227 E -115.3 100.7 5.0 0.022 0.205 A:Q13635:0.204
 CA
 8.285
 NH1
 CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 ARG C:100 C:123 53.0 0.236 E -115.3 100.6 6.0 0.027 0.209 A:Q13635:0.209
 CA
 8.285
 NH1
 CA
ARG F:100 F:123 53.0 0.236 E -115.3 100.7 5.0 0.022 0.214 D:Q13635:0.213
 CA
 8.284
 NH1
 CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 ARG C:100 C:123 26.0 0.116 E -124.3 138.7 0.0 0.0 0.116 B:Q13635:0.116
 CA
 8.470
 NH2
 CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 ARG B:101 C:123 17.0 0.076 E -134.5 148.9 0.0 0.0 0.076 C:Q13635:0.076
 CA
CA
 7.362
9.612
 NH2
NH2
 CA
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 ARG B:101 C:123 26.0 0.116 E -151.1 132.3 26.0 0.116 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 ARG A:101 A:123 20.0 0.089 E -128.8 132.1 20.0 0.089 0.0 SO4
HOH
 2.818
3.639
 NH2
CD
 O1
O
ARG B:101 B:123 16.0 0.071 E -126.0 130.1 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 ARG C:95 H:123 19.0 0.084 E -113.3 136.1 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 ARG A:95 A:123 18.0 0.08 E -126.2 138.6 14.0 0.062 0.018 C:None:0.018
 CA
HOH
 8.315
2.888
 NH2
NH2
 CA
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 ARG A:95 A:123 19.0 0.084 E -132.7 133.5 19.0 0.084 0.0 CL
HOH
 2.264
2.082
 HE
HH12
 CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 ARG B:211 B:123 31.0 0.138 E -135.2 141.4 1.0 0.004 0.134 A:Q13635+U6GSR1:0.133
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 ARG A:91 A:124 31.0 0.138 E -135.7 130.8 31.0 0.138 0.0 SO4
HOH
 1.788
1.912
 HH12
HE
 O1
O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 ARG A:103 A:124 21.0 0.093 E -125.0 133.6 0.0 0.0 0.093 D:Q4KMG0:0.093
 CA
HOH
 8.448
2.781
 NH2
NH1
 CA
O
ARG B:103 B:124 22.0 0.098 E -128.1 132.6 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 ARG B:99 H:124 25.0 0.111 E -123.9 141.6 6.0 0.027 0.084 A:Q3TDN0:0.084
 CA
SO4
 9.012
2.733
 NH2
NH2
 CA
O2
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:87 A:124 30.0 0.133 E -128.7 134.6 30.0 0.133 0.0 ASG
BDP
CA
ACT
HOH
 3.091
8.242
8.594
2.887
2.939
 NH2
NH2
NH2
NH1
NE
 OSC
O6B
CA
O
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ARG A:87 A:124 34.0 0.151 E -126.4 133.9 34.0 0.151 0.0 SGN
IDS
SGN
CA
HOH
 6.223
3.249
2.744
8.177
9.250
 NH2
NH2
NH1
NH1
CA
 O4
O3
O1S
CA
O
ARG B:87 B:124 27.0 0.12 E -127.1 134.2 27.0 0.12 0.0 SGN
IDS
SGN
IDS
CA
HOH
 2.804
3.982
3.389
9.542
8.547
3.114
 NH2
NH2
NH2
NH2
NH2
NE
 O1S
O6A
O4S
O3S
CA
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 ARG A:89 A:124 19.0 0.084 E -132.2 128.4 19.0 0.084 0.0 CA
HOH
 7.856
4.297
 NH2
NH1
 CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 ARG A:85 A:124 23.0 0.102 E -118.8 127.0 17.0 0.076 0.026 B:Q96QV1:0.027
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 ARG A:85 A:124 22.0 0.098 E -115.3 131.6 14.0 0.062 0.036 B:Q96QV1:0.036
 CA
 8.283
 NH2
 CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 ARG A:128 A:128 22.0 0.098 E -125.8 126.4