Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219922361 . C A CCDS33380.1:NM_002181.3:c.371gGt>gTt_NP_002172.2:p.124G>V Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 GLY A:109 B:124 86.0 1.0 T 98.1 -10.0 86.0 1.0 0.0 HOH
 2.933
 O
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLY A:109 B:124 82.0 1.0 T 93.3 -7.4 82.0 1.0 0.0 HOH
 2.855
 O
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLY A:109 B:124 85.0 1.0 T 98.9 -13.0 85.0 1.0 0.0 HOH
 3.037
 N
 O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 GLY A:109 B:124 85.0 1.0 T 93.5 -10.4 85.0 1.0 0.0 HOH
 3.156
 N
 O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLY A:100 A:124 81.0 1.0 T 82.4 2.6 81.0 1.0 0.0 HOH
 2.192
 H
 O
GLY B:100 B:124 85.0 1.0 T 89.8 -9.1 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLY A:100 B:124 86.0 1.0 T 94.5 -1.6 86.0 1.0 0.0 HOH
 2.085
 H
 O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLY A:100 A:124 83.0 1.0 T 91.6 -19.2 83.0 1.0 0.0 HOH
 8.308
 C
 O
GLY B:100 B:124 84.0 1.0 T 99.4 -19.3 NA NA NA
GLY C:100 C:124 89.0 1.0 T 77.6 14.5 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLY A:100 B:124 85.0 1.0 T 107.5 -3.6 85.0 1.0 0.0 HOH
 4.893
 N
 O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 GLY B:99 B:119 74.0 0.987 T 92.1 34.6 51.0 0.68 0.307 A:Q13635:0.307
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLY C:96 C:119 78.0 1.0 T 69.3 40.2 49.0 0.653 0.347 A:Q13635:0.253
B:Q13635:0.133
GLY F:96 F:119 77.0 1.0 T 69.3 40.3 48.0 0.64 0.36 D:Q13635:0.24
E:Q13635:0.133
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLY C:96 C:119 78.0 1.0 T 69.2 40.3 49.0 0.653 0.347 A:Q13635:0.253
B:Q13635:0.12
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLY C:96 C:119 78.0 1.0 T 69.3 40.2 49.0 0.653 0.347 A:Q13635:0.253
B:Q13635:0.133
GLY F:96 F:119 77.0 1.0 T 69.3 40.3 48.0 0.64 0.36 D:Q13635:0.24
E:Q13635:0.133
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 GLY C:96 C:119 76.0 1.0 T 88.9 10.4 50.0 0.667 0.333 A:Q13635:0.107
B:Q13635:0.24
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 GLY B:97 C:119 77.0 1.0 T 84.0 15.7 40.0 0.533 0.467 A:Q13635:0.107
C:Q13635:0.387
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 GLY B:97 C:119 63.0 0.84 T 78.6 0.9 63.0 0.84 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 GLY A:97 A:119 81.0 1.0 T 84.2 -8.7 81.0 1.0 0.0 HOH
 3.168
 C
 O
GLY B:97 B:119 82.0 1.0 T 86.7 7.1 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 GLY C:91 H:119 87.0 1.0 T 73.0 9.7 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 GLY A:91 A:119 82.0 1.0 T 92.2 -8.0 82.0 1.0 0.0 HOH
 2.901
 N
 O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 GLY A:91 A:119 79.0 1.0 T 85.7 -10.7 79.0 1.0 0.0 HOH
 2.749
 H
 O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 GLY B:207 B:119 77.0 1.0 T 102.6 -17.6 62.0 0.827 0.173 A:Q13635+U6GSR1:0.2
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 GLY A:87 A:120 75.0 1.0 T 94.8 -13.6 75.0 1.0 0.0 HOH
 1.891
 O
 H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 GLY A:99 A:120 84.0 1.0 T 92.9 -8.3 84.0 1.0 0.0 HOH
 2.923
 N
 O
GLY B:99 B:120 81.0 1.0 T 90.1 -7.1 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 GLY B:95 H:120 75.0 1.0 T 85.7 -3.1 75.0 1.0 0.0
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLY A:83 A:120 84.0 1.0 T 94.4 -5.7 84.0 1.0 0.0 HOH
 3.446
 O
 O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLY A:83 A:120 86.0 1.0 T 95.4 0.6 86.0 1.0 0.0 HOH
 3.050
 N
 O
GLY B:83 B:120 88.0 1.0 T 94.6 0.2 88.0 1.0 0.0 HOH
 8.581
 C
 O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 GLY A:85 A:120 82.0 1.0 T 100.0 -36.0 82.0 1.0 0.0 HOH
 4.579
 N
 O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 GLY A:81 A:120 81.0 1.0 T 61.4 22.6 81.0 1.0 0.0
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 GLY A:81 A:120 83.0 1.0 T 67.3 10.7 83.0 1.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 GLY A:124 A:124 83.0 1.0 T 85.7 -7.2