Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219924890 . G A CCDS33380.1:NM_002181.3:c.300gaC>gaT_NP_002172.2:p.100D>D Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 ASP A:85 B:100 0.0 0.0 G -58.8 -24.5 0.0 0.0 0.0 ZN
SO4
HOH
 9.900
8.453
2.605
 OD2
OD1
OD1
 ZN
O1
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ASP A:85 B:100 5.0 0.033 G -57.4 -27.6 5.0 0.033 0.0 ZN
HOH
 9.815
2.557
 OD2
OD1
 ZN
O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 ASP A:85 B:100 8.0 0.053 G -70.3 -15.5 8.0 0.053 0.0 SO4
HOH
 9.787
2.754
 OD1
N
 O3
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 GLU A:85 B:100 40.0 0.211 T -58.4 -21.8 40.0 0.211 0.0 SO4
SO4
HOH
 8.204
4.191
2.842
 OE2
OE2
OE2
 O3
O1
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ASP A:76 A:100 1.0 0.007 G -60.4 -27.5 1.0 0.007 0.0 ZN
CA
CA
CA
HOH
 9.945
2.443
4.388
9.816
2.025
 OD1
OD2
OD1
OD2
H
 ZN
CA
CA
CA
O
ASP B:76 B:100 1.0 0.007 G -63.6 -25.7 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ASP A:76 B:100 0.0 0.0 G -61.7 -23.7 0.0 0.0 0.0 CA
CA
HOH
 2.457
4.416
1.927
 OD2
OD1
H
 CA
CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ASP A:76 A:100 9.0 0.06 G -56.4 -21.5 9.0 0.06 0.0 HOH
 2.880
 O
 O
ASP B:76 B:100 14.0 0.093 G -62.5 -20.8 NA NA NA
ASP C:76 C:100 7.0 0.047 G -49.5 -39.1 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 ASP A:76 B:100 0.0 0.0 G -59.0 -35.0 0.0 0.0 0.0 CA
CA
HOH
 2.787
4.696
2.587
 OD1
OD1
OD1
 CA
CA
O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 ASP B:75 B:95 2.0 0.013 T -91.3 23.7 2.0 0.013 0.0 ZN
CA
CA
 9.779
4.522
2.501
 OD1
OD1
OD1
 ZN
CA
CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 ASP C:72 C:95 2.0 0.013 T -91.3 23.8 2.0 0.013 0.0 CA
CA
 4.523
2.501
 OD1
OD1
 CA
CA
ASP F:72 F:95 2.0 0.013 T -91.3 23.8 2.0 0.013 0.0 CA
CA
 4.523
2.501
 OD1
OD1
 CA
CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 ASP C:72 C:95 2.0 0.013 T -91.3 23.7 2.0 0.013 0.0 CA
CA
 4.522
2.501
 OD1
OD1
 CA
CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 ASP C:72 C:95 2.0 0.013 T -91.3 23.8 2.0 0.013 0.0 CA
CA
 4.523
2.501
 OD1
OD1
 CA
CA
ASP F:72 F:95 2.0 0.013 T -91.3 23.8 2.0 0.013 0.0 CA
CA
 4.523
2.501
 OD1
OD1
 CA
CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 ASP C:72 C:95 0.0 0.0 G -66.5 -4.6 0.0 0.0 0.0 CA
CA
 4.326
2.114
 OD1
OD2
 CA
CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 ASP B:73 C:95 1.0 0.007 T -74.5 -22.4 1.0 0.007 0.0 CA
CA
 2.759
2.388
 OD2
OD1
 CA
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 ASP B:73 C:95 4.0 0.027 G -80.0 -10.0 4.0 0.027 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 ASP A:73 A:95 10.0 0.067 G -54.7 -25.3 10.0 0.067 0.0 SO4
HOH
 8.843
2.533
 OD2
O
 O1
O
ASP B:73 B:95 0.0 0.0 G -54.8 -24.7 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 ASP C:67 H:95 0.0 0.0 G -60.8 -23.5 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 ASP A:67 A:95 0.0 0.0 G -57.8 -27.0 0.0 0.0 0.0 CA
CA
HOH
 2.365
4.249
2.821
 OD2
OD1
N
 CA
CA
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 ASP A:67 A:95 1.0 0.007 G -64.9 -16.0 1.0 0.007 0.0 DMS
MG
CL
HOH
 5.488
3.995
9.414
2.132
 N
OD1
OD2
H
 H12
MG
CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 ASP B:183 B:95 0.0 0.0 T -69.0 -13.7 0.0 0.0 0.0
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 ASP A:63 A:96 7.0 0.047 G -58.3 -28.1 7.0 0.047 0.0 ZN
SO4
HOH
 9.875
9.414
1.848
 OD1
OD2
O
 ZN
O4
H2
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 ASP A:75 A:96 1.0 0.007 G -62.9 -24.2 1.0 0.007 0.0 CA
CA
HOH
 2.465
4.363
2.792
 OD2
OD1
OD1
 CA
CA
O
ASP B:75 B:96 1.0 0.007 G -63.4 -20.5 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 ASP B:71 H:96 0.0 0.0 G -62.2 -23.0 0.0 0.0 0.0 CA
CA
ZN
SO4
 2.339
4.402
9.815
8.868
 OD2
OD1
OD1
OD2
 CA
CA
ZN
O1
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ASP A:59 A:96 0.0 0.0 G -61.6 -23.4 0.0 0.0 0.0 CA
CA
ACT
HOH
 4.392
2.396
9.417
2.824
 OD1
OD2
OD2
OD1
 CA
CA
OXT
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 ASP A:59 A:96 0.0 0.0 G -58.3 -24.7 0.0 0.0 0.0 IDS
SGN
CA
CA
HOH
 8.913
7.779
4.295
2.235
2.928
 OD2
OD2
OD1
OD2
OD1
 O1S
O1S
CA
CA
O
ASP B:59 B:96 0.0 0.0 G -58.7 -25.0 0.0 0.0 0.0 SGN
SGN
CA
CA
CL
HOH
 8.566
9.093
2.335
4.396
6.248
2.710
 OD2
OD2
OD2
OD1
N
N
 O2S
O6S
CA
CA
CL
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 ASP A:61 A:96 0.0 0.0 G -50.6 -46.3 0.0 0.0 0.0 CA
HOH
 2.302
1.836
 OD2
OD1
 CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 ASP A:57 A:96 16.0 0.107 -95.1 -5.6 16.0 0.107 0.0
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 ASP A:57 A:96 0.0 0.0 T -76.8 -9.0 0.0 0.0 0.0 CA
CA
 2.365
4.746
 OD2
OD1
 CA
CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 ASP A:100 A:100 2.0 0.013 G -54.1 -24.2