Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219924906 . T A CCDS33380.1:NM_002181.3:c.284gAg>gTg_NP_002172.2:p.95E>V Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 GLU A:80 B:95 41.0 0.216 T -75.4 -13.8 41.0 0.216 0.0 HOH
 2.894
 OE2
 O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 GLU A:80 B:95 76.0 0.4 T -79.8 -9.8 76.0 0.4 0.0 HOH
 2.611
 OE2
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 LYS A:80 B:95 54.0 0.27 T -96.4 1.9 54.0 0.27 0.0 HOH
 2.668
 NZ
 O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 GLU A:80 NA:NA DO NA DO DO DO NA NA NA
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:71 A:95 32.0 0.168 T -70.1 -25.8 20.0 0.105 0.063 D:Q4KMG0:0.063
 CA
CA
CA
HOH
 2.505
2.312
6.525
2.689
 OE2
OE2
C
OE1
 CA
CA
CA
O
GLU B:71 B:95 30.0 0.158 T -68.4 -21.0 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:71 B:95 28.0 0.147 T -71.1 -20.3 18.0 0.095 0.052 B:Q9BWV1:0.053
 CA
CA
HOH
 2.514
2.293
2.725
 OE2
OE2
HB3
 CA
CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:71 A:95 109.0 0.574 T -79.1 -3.9 109.0 0.574 0.0 HOH
 3.963
 CG
 O
GLU B:71 B:95 89.0 0.468 T -85.5 -8.7 NA NA NA
GLU C:71 C:95 81.0 0.426 T -59.8 -9.9 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 GLU A:71 B:95 32.0 0.168 T -83.8 -22.9 18.0 0.095 0.073 B:Q9BWV1:0.074
 CA
CA
HOH
 2.747
2.803
2.890
 OE2
OE2
OE2
 CA
CA
O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 GLU B:70 B:90 50.0 0.263 T -87.9 -11.8 50.0 0.263 0.0 CA
CA
 2.736
3.883
 OE2
OE1
 CA
CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:67 C:90 51.0 0.268 T -87.9 -11.8 43.0 0.226 0.042 A:Q13635:0.042
 CA
CA
 2.736
3.883
 OE2
OE1
 CA
CA
GLU F:67 F:90 51.0 0.268 T -87.9 -11.9 44.0 0.232 0.036 D:Q13635:0.037
 CA
CA
 2.735
3.883
 OE2
OE1
 CA
CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:67 C:90 50.0 0.263 T -87.9 -11.9 42.0 0.221 0.042 A:Q13635:0.042
 CA
CA
 2.736
3.883
 OE2
OE1
 CA
CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 GLU C:67 C:90 51.0 0.268 T -87.9 -11.8 43.0 0.226 0.042 A:Q13635:0.042
 CA
CA
 2.736
3.883
 OE2
OE1
 CA
CA
GLU F:67 F:90 51.0 0.268 T -87.9 -11.9 44.0 0.232 0.036 D:Q13635:0.037
 CA
CA
 2.735
3.883
 OE2
OE1
 CA
CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 GLU C:67 C:90 34.0 0.179 T -70.1 -21.9 25.0 0.132 0.047 B:Q13635:0.047
 CA
CA
 2.167
2.519
 OE2
OE1
 CA
CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 GLU B:68 C:90 48.0 0.253 T -77.3 -18.7 33.0 0.174 0.079 C:Q13635:0.079
 CA
CA
 3.841
2.595
 OE1
OE1
 CA
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 GLU B:68 C:90 62.0 0.326 T -97.4 -33.3 62.0 0.326 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 GLU A:68 A:90 104.0 0.547 T -73.8 -16.7 104.0 0.547 0.0 SO4
HOH
 8.476
2.558
 N
O
 O4
O
GLU B:68 B:90 40.0 0.211 T -76.7 -14.4 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 GLU C:62 H:90 35.0 0.184 S -65.0 -23.6 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 GLU A:62 A:90 33.0 0.174 T -72.6 -17.3 33.0 0.174 0.0 CA
CA
HOH
 2.377
2.343
2.823
 OE2
OE2
OE1
 CA
CA
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 GLU A:62 A:90 44.0 0.232 T -73.2 -13.8 44.0 0.232 0.0 DMS
MG
HOH
 9.041
2.072
2.690
 HB2
OE2
OE1
 H12
MG
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 GLU B:178 B:90 36.0 0.189 S -74.1 -25.5 34.0 0.179 0.01 A:Q13635+U6GSR1:0.011
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 GLU A:58 A:91 83.0 0.437 T -75.7 -16.3 83.0 0.437 0.0 HOH
 2.065
 H
 O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 GLU A:70 A:91 29.0 0.153 T -71.9 -20.9 19.0 0.1 0.053 D:Q4KMG0:0.053
 CA
CA
HOH
 2.573
2.345
2.797
 OE2
OE2
O
 CA
CA
O
GLU B:70 B:91 30.0 0.158 T -71.1 -23.1 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 GLU B:66 H:91 29.0 0.153 T -68.7 -27.7 29.0 0.153 0.0 CA
CA
 2.325
2.285
 OE2
OE1
 CA
CA
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLU A:54 A:91 37.0 0.195 T -69.6 -23.0 37.0 0.195 0.0 BDP
BDP
CA
CA
HOH
 9.424
9.666
2.347
2.546
2.799
 N
CA
OE2
OE2
OE1
 O6B
O6A
CA
CA
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 GLU A:54 A:91 37.0 0.195 T -64.6 -21.5 37.0 0.195 0.0 IDS
SGN
CA
CA
HOH
 8.716
8.849
2.351
2.515
3.049
 OE2
OE1
OE2
OE2
OE2
 O1S
O1S
CA
CA
O
GLU B:54 B:91 37.0 0.195 T -66.3 -21.4 29.0 0.153 0.042 A:Q62226:0.042
 SGN
SGN
CA
CA
CL
HOH
 8.046
9.801
2.602
2.304
8.557
2.828
 N
OE1
OE1
OE2
CB
OE2
 O2S
O6S
CA
CA
CL
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 GLU A:56 A:91 36.0 0.189 T -70.8 -33.2 36.0 0.189 0.0 CA
HOH
 3.181
3.265
 OE2
OE2
 CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 GLU A:52 NA:NA DO NA DO DO DO NA NA NA
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 GLU A:52 A:91 52.0 0.274 T -87.2 -17.1 52.0 0.274 0.0 CA
CA
 2.373
2.393
 OE1
OE1
 CA
CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 GLU A:95 A:95 67.0 0.353 T -72.5 -17.2