Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 219924916 . T A CCDS33380.1:NM_002181.3:c.274Aag>Tag_NP_002172.2:p.92K>* Homo sapiens indian hedgehog (IHH), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3k7g 1 Q14623 100.0 2e-127 X-RAY
 2011-01-26 LYS A:77 B:92 89.0 0.445 -63.0 -45.3 89.0 0.445 0.0 SO4
HOH
 5.106
2.727
 N
O
 O1
O
3k7i 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 LYS A:77 B:92 90.0 0.45 -63.2 -42.8 90.0 0.45 0.0 HOH
 3.029
 NZ
 O
3k7h 1 Q14623 99.43 6e-127 X-RAY
 2011-01-26 LYS A:77 B:92 86.0 0.43 -59.6 -39.9 86.0 0.43 0.0 SO4
HOH
 3.435
2.867
 CE
O
 O4
O
3k7j 1 Q14623 99.43 7e-127 X-RAY
 2011-01-26 LYS A:77 B:92 156.0 0.78 -55.8 360.0 156.0 0.78 0.0 SO4
SO4
HOH
 3.288
2.926
3.717
 NZ
CE
NZ
 O2
O4
O
3n1f 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:68 A:92 98.0 0.49 -58.2 -46.8 11.0 0.055 0.435 D:Q4KMG0:0.435
 CA
CA
CA
HOH
 4.827
8.407
6.566
2.883
 CB
CD
O
O
 CA
CA
CA
O
LYS B:68 B:92 94.0 0.47 -55.7 -52.3 NA NA NA
3n1m 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:68 B:92 100.0 0.5 -57.9 -50.0 13.0 0.065 0.435 B:Q9BWV1:0.435
 CA
CA
HOH
 3.957
7.545
2.710
 HB3
HD3
O
 CA
CA
O
3n1o 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:68 A:92 100.0 0.5 -55.4 -45.1 100.0 0.5 0.0 HOH
 3.224
 O
 O
LYS B:68 B:92 86.0 0.43 -54.8 -39.8 NA NA NA
LYS C:68 C:92 87.0 0.435 -58.7 -41.0 NA NA NA
3n1p 1 Q14623 99.4 7e-120 X-RAY
 2010-06-02 LYS A:68 B:92 94.0 0.47 -56.8 -52.3 11.0 0.055 0.415 B:Q9BWV1:0.415
 CA
CA
HOH
 4.689
8.341
6.779
 CD
CD
CE
 CA
CA
O
6dmy 2 Q15465 88.57 1e-113 EM
 2018-07-11 LYS B:67 B:87 97.0 0.485 -64.7 -55.3 39.0 0.195 0.29 A:Q13635:0.29
 CA
CA
 8.959
5.424
 CD
CD
 CA
CA
6n7g 2 Q15465 88.57 2e-113 EM
 2019-05-29 LYS C:64 C:87 111.0 0.555 -64.8 -55.2 28.0 0.14 0.415 A:Q13635:0.415
 CA
CA
 8.959
5.425
 CD
CD
 CA
CA
LYS F:64 F:87 111.0 0.555 -64.8 -55.2 28.0 0.14 0.415 D:Q13635:0.415
 CA
CA
 8.959
5.424
 CD
CD
 CA
CA
6n7h 2 Q15465 88.57 2e-113 EM
 2019-05-29 LYS C:64 C:87 112.0 0.56 -64.8 -55.2 28.0 0.14 0.42 A:Q13635:0.42
 CA
CA
 8.959
5.425
 CD
CD
 CA
CA
6n7k 2 Q15465 88.57 2e-113 EM
 2019-05-29 LYS C:64 C:87 111.0 0.555 -64.8 -55.2 28.0 0.14 0.415 A:Q13635:0.415
 CA
CA
 8.959
5.425
 CD
CD
 CA
CA
LYS F:64 F:87 111.0 0.555 -64.8 -55.2 28.0 0.14 0.415 D:Q13635:0.415
 CA
CA
 8.959
5.424
 CD
CD
 CA
CA
6rvd 2 Q15465 88.57 2e-113 EM
 2019-10-02 LYS C:64 C:87 109.0 0.545 -70.1 -49.4 14.0 0.07 0.475 B:Q13635:0.475
 CA
CA
 9.014
5.101
 CD
CB
 CA
CA
6e1h 2 Q15465 88.57 2e-113 EM
 2018-08-29 LYS B:65 C:87 103.0 0.515 -66.5 -50.8 14.0 0.07 0.445 C:Q13635:0.445
 CA
CA
 4.563
6.697
 CB
CB
 CA
CA
6oev 2 Q15465 88.57 2e-113 EM
 2019-04-17 LYS B:65 C:87 80.0 0.4 -69.7 -61.0 80.0 0.4 0.0
3m1n 1 Q15465 88.51 3e-112 X-RAY
 2010-03-16 LYS A:65 A:87 90.0 0.45 -55.0 -44.7 90.0 0.45 0.0 SO4
HOH
 3.221
2.746
 CG
NZ
 O1
O
LYS B:65 B:87 94.0 0.47 -59.6 -48.3 NA NA NA
3ho5 2 Q15465 89.76 2e-110 X-RAY
 2009-06-23 LYS C:59 H:87 95.0 0.475 -60.4 -44.5 NA NA NA
3mxw 1 Q15465 89.76 2e-110 X-RAY
 2010-05-26 LYS A:59 A:87 90.0 0.45 -54.8 -52.7 31.0 0.155 0.295 C:None:0.295
 CA
CA
HOH
 4.997
8.778
3.365
 CB
CD
NZ
 CA
CA
O
6pjv 1 Q15465 89.76 2e-110 X-RAY
 2019-11-13 LYS A:59 A:87 105.0 0.525 -56.9 -44.3 105.0 0.525 0.0 MG
CL
HOH
 6.933
2.861
2.334
 HD3
HA
HZ2
 MG
CL
O
6rmg 2 Q15465 89.76 8e-110 EM
 2019-10-09 LYS B:175 B:87 88.0 0.44 -80.7 -45.4 29.0 0.145 0.295 A:Q13635+U6GSR1:0.295
1vhh 1 Q62226 90.74 3e-108 X-RAY
 1996-01-29 LYS A:55 A:88 89.0 0.445 -59.4 -45.3 89.0 0.445 0.0 SO4
HOH
 3.419
1.729
 CE
HZ2
 O4
O
3d1m 1 Q62226 89.22 8e-108 X-RAY
 2008-09-23 LYS A:67 A:88 99.0 0.495 -54.5 -50.7 13.0 0.065 0.43 D:Q4KMG0:0.43
 CA
CA
HOH
 4.816
8.339
2.626
 CB
CD
O
 CA
CA
O
LYS B:67 B:88 96.0 0.48 -55.6 -50.0 NA NA NA
7rpk 2 Q62226 89.7 3e-107 EM
 2021-10-27 LYS B:63 H:88 99.0 0.495 -107.4 70.9 20.0 0.1 0.395 A:Q3TDN0:0.395
 CA
CA
SO4
 3.349
6.777
2.722
 O
O
NZ
 CA
CA
O2
4c4m 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 LYS A:51 A:88 105.0 0.525 -62.6 -49.6 105.0 0.525 0.0 ASG
BDP
ASG
CA
CA
ACT
HOH
 3.701
5.725
7.227
9.070
5.081
3.198
2.731
 CE
CE
NZ
CD
CB
NZ
O
 OSA
O6B
C6
CA
CA
OXT
O
4c4n 1 Q62226 91.67 2e-105 X-RAY
 2013-10-02 LYS A:51 A:88 99.0 0.495 -61.1 -49.1 99.0 0.495 0.0 IDS
SGN
IDS
SGN
CA
CA
HOH
 9.054
5.614
2.433
3.268
8.746
4.763
8.197
 NZ
NZ
NZ
CG
CD
CB
N
 O6A
O5S
O1S
O1S
CA
CA
O
LYS B:51 B:88 101.0 0.505 -61.3 -49.6 101.0 0.505 0.0 SGN
IDS
SGN
IDS
CA
CA
HOH
 3.836
4.534
2.828
5.901
4.945
8.772
3.960
 CG
NZ
NZ
NZ
CD
NZ
CA
 O1S
O6B
O6S
O3S
CA
CA
O
3n1r 1 Q62226 91.67 6e-105 X-RAY
 2010-06-02 LYS A:53 A:88 114.0 0.57 -43.3 -63.5 114.0 0.57 0.0 CA
HOH
 4.159
4.216
 CB
O
 CA
O
2wg4 1 Q62226 91.61 1e-104 X-RAY
 2009-06-30 LYS A:49 A:88 126.0 0.63 -63.5 -53.1 57.0 0.285 0.345 B:Q96QV1:0.345
2wfx 1 Q62226 92.11 3e-103 X-RAY
 2009-06-30 LYS A:49 A:88 102.0 0.51 -61.9 -46.3 46.0 0.23 0.28 B:Q96QV1:0.28
 CA
CA
 5.169
9.404
 CB
C
 CA
CA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q14623-f1 1 Q14623 100.0 0.0 LYS A:92 A:92 67.0 0.335 -71.2 -49.4