Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 242794796 | . | A | C | CCDS33428.1:NM_005018.2:c.413cTg>cGg_NP_005009.2:p.138L>R | Homo sapiens programmed cell death 1 (PDCD1), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5wt9 | 3 | Q15116 | 100.0 | 4e-121 |
X-RAY |
2017-02-15 | LEU | C:138 | G:138 | 148.0 | 0.871 | -61.2 | 170.3 | 148.0 | 0.871 | 0.0 |
HOH |
9.574 |
N |
O |
|||
6jbt | 1 | Q15116 | 100.0 | 1e-107 |
X-RAY |
2019-06-19 | LEU | A:119 | F:119 | 149.0 | 0.876 | -69.6 | 156.0 | 149.0 | 0.876 | 0.0 |
HOH |
3.329 |
N |
O |
|||
6jjp | 3 | Q15116 | 100.0 | 5e-105 |
X-RAY |
2019-10-30 | LEU | C:118 | C:138 | 147.0 | 0.865 | -66.0 | 153.2 | 147.0 | 0.865 | 0.0 | |||||||
LEU | F:118 | F:138 | 151.0 | 0.888 | -64.9 | 155.3 | NA | NA | NA | ||||||||||||||
7cgw | 3 | Q15116 | 100.0 | 4e-103 |
X-RAY |
2021-04-07 | LEU | C:114 | C:138 | 119.0 | 0.7 | -97.9 | 160.8 | 119.0 | 0.7 | 0.0 | |||||||
LEU | F:114 | P:138 | 121.0 | 0.712 | -92.2 | 160.4 | NA | NA | NA | ||||||||||||||
6k0y | 3 | Q15116 | 99.3 | 2e-100 |
X-RAY |
2019-12-11 | LEU | C:114 | C:138 | 158.0 | 0.929 | -61.6 | 154.8 | 158.0 | 0.929 | 0.0 |
HOH |
2.853 |
N |
O |
|||
6xkr | 3 | Q15116 | 100.0 | 2e-91 |
X-RAY |
2020-09-09 | LEU | C:107 | P:138 | 148.0 | 0.871 | -82.0 | 170.2 | 148.0 | 0.871 | 0.0 |
HOH |
3.005 |
N |
O |
|||
3rrq | 1 | Q15116 | 99.22 | 5e-90 |
X-RAY |
2012-05-16 | LEU | A:107 | A:138 | 156.0 | 0.918 | -63.3 | 157.0 | 156.0 | 0.918 | 0.0 |
HOH |
3.005 |
N |
O |
|||
5b8c | 3 | Q15116 | 99.22 | 8e-90 |
X-RAY |
2016-10-26 | LEU | C:109 | C:138 | 152.0 | 0.894 | -74.0 | 161.0 | 152.0 | 0.894 | 0.0 |
HOH |
2.875 |
N |
O |
|||
LEU | F:109 | F:138 | 150.0 | 0.882 | -73.3 | 159.9 | NA | NA | NA | ||||||||||||||
LEU | I:109 | I:138 | 141.0 | 0.829 | -74.5 | 160.6 | NA | NA | NA | ||||||||||||||
LEU | L:109 | L:138 | 149.0 | 0.876 | -73.8 | 159.8 | NA | NA | NA | ||||||||||||||
7vux | 1 | Q15116 | 99.22 | 8e-90 |
X-RAY |
2021-11-17 | LEU | A:108 | A:138 | 150.0 | 0.882 | -62.0 | 153.6 | 150.0 | 0.882 | 0.0 |
HOH |
3.116 |
O |
O |
|||
5ggr | 3 | Q15116 | 99.2 | 7e-87 |
X-RAY |
2016-11-09 | LEU | E:113 | Y:138 | 149.0 | 0.876 | -91.3 | 117.7 | 149.0 | 0.876 | 0.0 | |||||||
LEU | F:113 | Z:138 | 139.0 | 0.818 | -94.0 | 140.1 | NA | NA | NA | ||||||||||||||
5ggs | 3 | Q15116 | 99.19 | 3e-85 |
X-RAY |
2016-11-09 | LEU | E:113 | Y:138 | 151.0 | 0.888 | -68.1 | 148.8 | NA | NA | NA | |||||||
LEU | F:113 | Z:138 | 155.0 | 0.912 | -64.0 | 155.6 | 155.0 | 0.912 | 0.0 |
HOH |
3.892 |
N |
O |
||||||||||
7bxa | 1 | Q15116 | 98.37 | 8e-85 |
X-RAY |
2020-06-10 | LEU | A:110 | A:138 | 138.0 | 0.812 | -67.3 | 144.6 | 138.0 | 0.812 | 0.0 | |||||||
LEU | D:110 | P:138 | 141.0 | 0.829 | -69.3 | 167.2 | NA | NA | NA | ||||||||||||||
7cu5 | 2 | Q15116 | 100.0 | 1e-82 |
X-RAY |
2020-10-14 | LEU | B:109 | E:138 | 132.0 | 0.776 | -83.9 | 135.5 | NA | NA | NA | |||||||
LEU | D:109 | Q:138 | 148.0 | 0.871 | -70.0 | 131.3 | 148.0 | 0.871 | 0.0 | ||||||||||||||
4zqk | 2 | Q15116 | 99.15 | 2e-81 |
X-RAY |
2015-11-04 | LEU | B:106 | B:138 | 155.0 | 0.912 | -59.0 | 156.3 | 155.0 | 0.912 | 0.0 | |||||||
6hig | 3 | Q15116 | 99.15 | 2e-81 |
X-RAY |
2019-06-05 | LEU | C:106 | B:138 | 145.0 | 0.853 | -73.5 | 162.7 | 10.0 | 0.059 | 0.794 |
B:None:0.412 A:None:0.518 |
HOH |
3.031 |
N |
O |
||
6j15 | 1 | Q15116 | 100.0 | 2e-81 |
X-RAY |
2019-11-06 | LEU | A:111 | C:138 | 151.0 | 0.888 | -67.4 | 153.0 | 151.0 | 0.888 | 0.0 | |||||||
LEU | B:111 | D:138 | 137.0 | 0.806 | -61.3 | 152.2 | NA | NA | NA | ||||||||||||||
7e9b | 3 | Q15116 | 100.0 | 1e-80 |
X-RAY |
2021-07-28 | LEU | C:107 | C:138 | 149.0 | 0.876 | -62.2 | 156.9 | 149.0 | 0.876 | 0.0 |
HOH |
2.908 |
N |
O |
|||
2m2d | 1 | Q15116 | 99.15 | 1e-80 |
NMR |
2013-02-27 | LEU | A:106 | A:138 | 96.0 | 0.565 | E | -69.7 | 159.9 | 96.0 | 0.565 | 0.0 | ||||||
6j14 | 3 | Q15116 | 100.0 | 2e-80 |
X-RAY |
2019-11-06 | LEU | C:106 | G:138 | 150.0 | 0.882 | -63.7 | 160.8 | 150.0 | 0.882 | 0.0 |
HOH |
2.562 |
N |
O |
|||
6umv | 1 | Q15116 | 94.35 | 7e-80 |
X-RAY |
2019-11-27 | LEU | A:107 | A:138 | 152.0 | 0.894 | -67.3 | 161.1 | 152.0 | 0.894 | 0.0 |
CL HOH |
3.255 3.471 |
N O |
CL O |
|||
6umu | 1 | Q15116 | 93.55 | 9e-79 |
X-RAY |
2019-11-27 | LEU | A:107 | A:138 | 152.0 | 0.894 | -71.7 | 163.8 | 152.0 | 0.894 | 0.0 |
CL HOH |
3.243 3.486 |
N O |
CL O |
|||
5jxe | 1 | Q15116 | 99.12 | 2e-78 |
X-RAY |
2016-08-10 | LEU | A:106 | A:138 | 137.0 | 0.806 | -70.2 | 112.9 | 137.0 | 0.806 | 0.0 | |||||||
LEU | B:106 | B:138 | 127.0 | 0.747 | -82.5 | 133.9 | NA | NA | NA | ||||||||||||||
5ius | 1 | Q15116 | 90.32 | 2e-76 |
X-RAY |
2016-09-28 | LEU | A:117 | A:138 | 152.0 | 0.894 | -72.2 | 163.8 | 152.0 | 0.894 | 0.0 | |||||||
LEU | B:117 | B:138 | 148.0 | 0.871 | -75.8 | 163.5 | NA | NA | NA | ||||||||||||||
6umt | 1 | Q15116 | 94.07 | 2e-75 |
X-RAY |
2019-11-27 | LEU | A:125 | A:138 | 157.0 | 0.924 | -59.7 | 152.1 | 157.0 | 0.924 | 0.0 |
HOH |
3.020 |
N |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q15116-f1 | 1 | Q15116 | 100.0 | 0.0 | LEU | A:138 | A:138 | 149.0 | 0.876 | -59.6 | 153.8 |