Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 28999810 . C A CCDS33169.1:NM_002709.2:c.146cCt>cAt_NP_002700.1:p.49P>H Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
2004-06-22 PRO A:52 A:50 79.0 0.545 -53.0 164.9 79.0 0.545 0.0 HOH
3.191
O
O
1fjm 1 P08129 88.79 0.0 X-RAY
1996-06-20 PRO A:50 A:50 78.0 0.538 -63.0 151.8 78.0 0.538 0.0 HOH
2.768
O
O
PRO B:50 B:50 78.0 0.538 -58.1 148.0 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
2012-09-19 PRO A:51 A:50 67.0 0.462 -64.3 150.6 67.0 0.462 0.0
PRO B:51 B:50 74.0 0.51 -61.1 153.5 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
2018-11-21 PRO A:51 A:50 77.0 0.531 -62.2 159.9 77.0 0.531 0.0 HOH
2.650
O
O
6g0j 1 P62136 88.79 0.0 X-RAY
2018-11-21 PRO A:51 A:50 82.0 0.566 -65.1 161.5 82.0 0.566 0.0 HOH
2.707
O
O
3egg 1 P62136 89.26 0.0 X-RAY
2010-03-23 PRO A:49 A:50 78.0 0.538 -63.0 151.8 78.0 0.538 0.0 GOL
HOH
3.430
3.595
CD
CA
C1
O
PRO B:49 B:50 77.0 0.531 -66.3 155.0 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
2010-03-23 PRO A:49 A:50 78.0 0.538 -67.0 152.6 78.0 0.538 0.0 GOL
HOH
4.095
2.928
CD
O
C2
O
PRO B:49 B:50 77.0 0.531 -68.9 158.7 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
2010-03-23 PRO A:49 A:50 79.0 0.545 -64.0 152.9 79.0 0.545 0.0 HOH
2.761
O
O
PRO B:49 B:50 75.0 0.517 -62.7 157.5 75.0 0.517 0.0 HOH
2.691
O
O
6ghm 1 P62136 89.26 0.0 X-RAY
2019-02-27 PRO A:49 A:50 80.0 0.552 -67.7 153.5 80.0 0.552 0.0 EDO
HOH
3.800
2.764
CD
O
O1
O
PRO B:49 B:50 82.0 0.566 -62.8 152.2 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
2019-05-15 PRO A:59 A:50 79.0 0.545 -65.0 150.8 58.0 0.4 0.145 D:Q8WUF5:0.145
PRO B:59 B:50 78.0 0.538 -65.7 151.0 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
2020-11-18 PRO A:51 A:50 77.0 0.531 -66.2 156.0 77.0 0.531 0.0 HOH
2.864
O
O
5zqv 1 P62137 89.23 0.0 X-RAY
2019-03-13 PRO A:50 A:50 74.0 0.51 -58.7 144.5 74.0 0.51 0.0
PRO B:50 B:50 74.0 0.51 -64.0 143.8 NA NA NA
PRO C:50 C:50 83.0 0.572 -64.4 144.3 83.0 0.572 0.0
PRO D:50 D:50 76.0 0.524 -62.7 140.9 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
2015-03-25 PRO D:50 D:50 77.0 0.531 -63.0 153.4 NA NA NA
PRO F:50 F:50 76.0 0.524 -63.1 153.4 NA NA NA
PRO H:50 H:50 78.0 0.538 -63.1 153.4 NA NA NA
PRO J:50 J:50 77.0 0.531 -63.1 153.3 77.0 0.531 0.0
PRO N:50 N:50 77.0 0.531 -63.0 153.4 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
2002-05-22 PRO A:50 A:50 75.0 0.517 -53.2 156.4 75.0 0.517 0.0 HOH
2.844
O
O
PRO B:50 B:50 78.0 0.538 -58.8 152.8 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
2001-08-15 PRO A:50 A:50 81.0 0.559 -60.1 154.6 81.0 0.559 0.0 HOH
2.729
O
O
2bcd 1 P36873 89.06 0.0 X-RAY
2006-01-17 PRO A:50 A:50 80.0 0.552 -54.4 148.5 80.0 0.552 0.0 HOH
2.865
O
O
2bdx 1 P36873 89.06 0.0 X-RAY
2006-01-17 PRO A:50 A:50 84.0 0.579 -64.5 156.1 84.0 0.579 0.0 HOH
2.788
O
O
4ut2 1 P36873 89.06 0.0 X-RAY
2015-07-22 PRO A:50 A:50 81.0 0.559 -65.3 152.8 81.0 0.559 0.0 HOH
2.908
O
O
PRO B:50 B:50 80.0 0.552 -65.8 153.4 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
2015-07-22 PRO A:50 A:50 82.0 0.566 -65.0 157.4 82.0 0.566 0.0 HOH
2.724
O
O
4ut3 2 P36873 89.06 0.0 X-RAY
2015-07-22 PRO B:50 B:50 78.0 0.538 -66.2 157.9 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
2007-07-17 PRO A:56 A:50 81.0 0.559 -60.9 154.6 37.0 0.255 0.304 B:Q9DCL8:0.303
HOH
2.955
O
O
PRO C:56 B:50 78.0 0.538 -64.9 157.2 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
2007-07-17 PRO A:56 A:50 81.0 0.559 -59.6 154.5 36.0 0.248 0.311 B:Q9DCL8:0.31
HOH
2.830
O
O
PRO C:56 B:50 80.0 0.552 -58.5 147.5 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
2020-09-30 PRO A:49 D:49 72.0 0.497 -61.9 151.6 72.0 0.497 0.0 HOH
2.536
O
O
PRO B:49 A:49 62.0 0.428 -63.2 149.5 NA NA NA
PRO C:49 F:49 73.0 0.503 -62.1 150.8 NA NA NA
PRO D:49 I:49 78.0 0.538 -65.5 155.8 NA NA NA
PRO E:49 L:49 78.0 0.538 -62.1 155.6 NA NA NA
PRO F:49 O:49 72.0 0.497 -67.0 151.0 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
2012-10-31 PRO A:49 A:50 80.0 0.552 -60.7 152.5 80.0 0.552 0.0 GOL
GOL
HOH
9.011
2.095
2.612
HD2
HD2
HB3
O3
H12
O
PRO C:49 C:50 82.0 0.566 -64.8 152.6 NA NA NA
PRO E:49 E:50 79.0 0.545 -60.1 148.0 NA NA NA
PRO G:49 G:50 80.0 0.552 -58.7 147.3 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
2020-09-30 PRO A:49 A:50 78.0 0.538 -62.5 151.5 78.0 0.538 0.0 HOH
2.701
HB3
O
PRO C:49 B:50 80.0 0.552 -68.4 155.2 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
2019-09-18 PRO A:55 A:50 84.0 0.579 -59.5 157.9 84.0 0.579 0.0 CL
HOH
6.355
2.800
C
O
CL
O
PRO B:55 B:50 84.0 0.579 -59.4 155.9 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
2019-09-18 PRO A:55 A:50 80.0 0.552 -62.0 150.9 80.0 0.552 0.0 HOH
2.935
O
O
3n5u 1 P62136 92.0 0.0 X-RAY
2010-08-11 PRO A:50 A:50 78.0 0.538 -67.2 148.3 78.0 0.538 0.0
PRO B:50 B:50 77.0 0.531 -67.1 147.4 77.0 0.531 0.0
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
2020-09-30 PRO A:49 A:50 77.0 0.531 -65.1 155.2 77.0 0.531 0.0 EDO
HOH
4.923
2.696
C
HB3
H11
O
PRO C:49 B:50 80.0 0.552 -66.8 156.0 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
2020-09-30 PRO A:49 A:50 77.0 0.531 -62.8 155.0 77.0 0.531 0.0 HOH
2.598
HB3
O
PRO C:49 B:50 80.0 0.552 -67.3 155.1 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
2008-11-04 PRO A:49 A:50 80.0 0.552 -59.7 152.0 80.0 0.552 0.0 GOL
HOH
3.269
2.756
CD
O
O2
O
PRO B:49 B:50 74.0 0.51 -65.8 153.0 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
2008-11-04 PRO A:49 A:50 77.0 0.531 -60.7 154.3 77.0 0.531 0.0 GOL
AZI
HOH
3.330
7.152
2.829
CG
CA
O
O1
N1
O
PRO B:49 B:50 78.0 0.538 -59.3 149.4 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
2014-03-26 PRO A:49 A:50 80.0 0.552 -66.3 156.1 80.0 0.552 0.0 HOH
2.800
O
O
PRO B:49 B:50 79.0 0.545 -67.8 154.2 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
2014-03-26 PRO A:49 A:50 79.0 0.545 -61.0 152.8 79.0 0.545 0.0 GOL
HOH
3.685
3.000
CD
O
O3
O
4mp0 1 P62136 92.57 0.0 X-RAY
2014-03-26 PRO A:49 A:50 79.0 0.545 -60.3 149.1 79.0 0.545 0.0 GOL
HOH
3.616
2.853
CG
O
O3
O
PRO B:49 C:50 79.0 0.545 -60.3 149.7 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
2015-07-01 PRO A:49 A:50 69.0 0.476 -63.5 152.3 69.0 0.476 0.0 GOL
HOH
3.677
2.996
CD
O
O3
O
PRO C:49 C:50 69.0 0.476 -62.6 152.7 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
2016-10-05 PRO A:49 A:50 78.0 0.538 -58.6 152.2 78.0 0.538 0.0 HOH
2.965
O
O
PRO C:49 C:50 81.0 0.559 -58.8 153.0 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
2017-11-29 PRO A:49 A:50 83.0 0.572 -63.3 152.6 83.0 0.572 0.0 DMS
HOH
3.637
2.879
CD
O
C1
O
PRO B:49 B:50 80.0 0.552 -64.0 154.0 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
2019-01-23 PRO A:49 A:50 77.0 0.531 -62.2 153.0 39.0 0.269 0.262 B:Q05C46:0.262
HOH
2.908
O
O
PRO C:49 C:50 79.0 0.545 -57.5 151.2 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
2019-01-23 PRO A:49 A:50 76.0 0.524 -65.7 153.6 76.0 0.524 0.0 HOH
2.832
O
O
6zee 1 P62136 92.57 0.0 X-RAY
2020-09-30 PRO A:49 P:50 78.0 0.538 -69.7 153.5 78.0 0.538 0.0 HOH
2.792
O
O
PRO B:49 Q:50 74.0 0.51 -66.3 155.0 74.0 0.51 0.0 HOH
2.479
HG2
O
PRO C:49 B:50 82.0 0.566 -62.0 153.7 82.0 0.566 0.0 HOH
2.550
HB3
O
PRO D:49 A:50 76.0 0.524 -71.6 154.7 76.0 0.524 0.0 16P
EDO
EDO
HOH
2.253
2.288
2.854
2.769
HA
HA
HD2
HG2
H51
HO1
HO2
O
PRO E:49 I:50 82.0 0.566 -60.2 154.6 82.0 0.566 0.0 HOH
2.467
HB3
O
PRO F:49 K:50 81.0 0.559 -62.9 154.0 81.0 0.559 0.0 EDO
GOL
HOH
2.116
4.503
2.450
HD2
HA
HA
HO2
H11
O
6zef 1 P62136 92.57 0.0 X-RAY
2020-09-30 PRO A:49 A:50 73.0 0.503 -61.1 153.2 73.0 0.503 0.0 EDO
EDO
EDO
CL
HOH
8.673
2.262
2.569
6.105
2.617
HG2
HG2
HD2
HA
HB3
HO1
H21
H22
CL
O
PRO B:49 B:50 71.0 0.49 -62.0 152.7 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
2016-10-05 PRO A:47 A:50 76.0 0.524 -65.3 153.6 76.0 0.524 0.0 GOL
NA
HOH
3.482
9.881
2.807
CG
CB
O
O3
NA
O
5j28 1 P36873 92.57 0.0 X-RAY
2016-10-05 PRO A:47 A:50 82.0 0.566 -62.9 148.5 82.0 0.566 0.0 NA
HOH
9.979
2.891
CB
O
NA
O
PRO B:47 B:50 78.0 0.538 -61.8 158.9 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
2019-09-18 PRO A:49 A:50 80.0 0.552 -64.6 153.6 80.0 0.552 0.0 HOH
2.782
O
O
PRO B:49 B:50 74.0 0.51 -64.2 152.2 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
2019-09-18 PRO A:49 A:50 75.0 0.517 -62.1 152.6 75.0 0.517 0.0 HOH
2.837
O
O
PRO B:49 B:50 75.0 0.517 -61.8 152.3 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
2019-09-18 PRO A:49 A:50 79.0 0.545 -63.6 153.8 79.0 0.545 0.0 HOH
2.816
O
O
PRO B:49 B:50 78.0 0.538 -64.8 151.0 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
2019-09-18 PRO A:49 A:50 79.0 0.545 -63.3 155.0 79.0 0.545 0.0 GOL
HOH
3.597
2.895
CD
O
C1
O
PRO B:49 B:50 78.0 0.538 -64.4 157.0 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
2019-03-13 PRO A:44 A:50 76.0 0.524 -66.8 151.8 76.0 0.524 0.0
PRO B:44 B:50 77.0 0.531 -65.5 147.6 NA NA NA
PRO C:44 C:50 80.0 0.552 -63.1 152.5 NA NA NA
PRO D:44 D:50 76.0 0.524 -66.7 151.5 NA NA NA
PRO E:44 E:50 80.0 0.552 -68.2 151.9 NA NA NA
PRO F:44 F:50 79.0 0.545 -64.0 148.3 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
2015-03-25 PRO A:45 A:50 74.0 0.51 -64.2 154.2 74.0 0.51 0.0 HOH
2.806
O
O
PRO C:45 C:50 78.0 0.538 -63.4 153.2 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
2015-03-25 PRO A:45 A:50 76.0 0.524 -60.6 154.1 76.0 0.524 0.0 HOH
2.737
O
O
PRO C:45 C:50 79.0 0.545 -63.5 153.0 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
2015-03-25 PRO A:45 A:50 84.0 0.579 -65.2 152.4 84.0 0.579 0.0 HOH
2.548
HG2
O
7nzm 2 P62139 92.52 0.0 EM
2021-09-29 PRO B:44 B:50 90.0 0.621 -66.3 156.6 90.0 0.621 0.0
1u32 1 P36873 90.78 0.0 X-RAY
2004-08-17 PRO A:45 A:50 75.0 0.517 -60.1 156.0 75.0 0.517 0.0 HOH
2.750
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 PRO A:49 A:49 82.0 0.566 -57.3 151.8
af-p62136-f1 1 P62136 88.79 0.0 PRO A:50 A:50 78.0 0.538 -57.0 152.1
af-p36873-f1 1 P36873 89.06 0.0 PRO A:50 A:50 80.0 0.552 -56.8 152.9