Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 28999830 . G A CCDS33169.1:NM_002709.2:c.166Gca>Aca_NP_002700.1:p.56A>T Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
 2004-06-22 ALA A:59 A:57 2.0 0.017 S -60.5 156.2 2.0 0.017 0.0 HOH
 3.381
 O
 O
1fjm 1 P08129 88.79 0.0 X-RAY
 1996-06-20 ALA A:57 A:57 12.0 0.104 S -99.0 161.6 12.0 0.104 0.0 HOH
 5.060
 N
 O
ALA B:57 B:57 15.0 0.13 S -85.0 159.6 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
 2012-09-19 ALA A:58 A:57 16.0 0.139 S -86.5 160.5 16.0 0.139 0.0 HOH
 6.612
 C
 O
ALA B:58 B:57 6.0 0.052 S -65.5 160.3 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
 2018-11-21 ALA A:58 A:57 10.0 0.087 S -71.0 155.3 10.0 0.087 0.0 HOH
 5.560
 N
 O
6g0j 1 P62136 88.79 0.0 X-RAY
 2018-11-21 ALA A:58 A:57 15.0 0.13 S -67.9 155.7 15.0 0.13 0.0 HOH
 2.747
 O
 O
3egg 1 P62136 89.26 0.0 X-RAY
 2010-03-23 ALA A:56 A:57 17.0 0.148 S -59.4 154.6 17.0 0.148 0.0 GOL
HOH
 6.430
3.287
 C
O
 O3
O
ALA B:56 B:57 18.0 0.157 S -64.7 155.5 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
 2010-03-23 ALA A:56 A:57 16.0 0.139 S -64.2 155.6 16.0 0.139 0.0 GOL
GOL
HOH
 6.279
9.706
3.266
 C
N
O
 O3
O1
O
ALA B:56 B:57 17.0 0.148 S -65.5 154.5 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
 2010-03-23 ALA A:56 A:57 17.0 0.148 S -64.1 156.2 17.0 0.148 0.0 HOH
 2.988
 O
 O
ALA B:56 B:57 15.0 0.13 S -65.5 154.6 15.0 0.13 0.0 HOH
 2.772
 O
 O
6ghm 1 P62136 89.26 0.0 X-RAY
 2019-02-27 ALA A:56 A:57 15.0 0.13 S -74.6 157.8 15.0 0.13 0.0 GOL
HOH
 3.387
6.437
 O
C
 O3
O
ALA B:56 B:57 16.0 0.139 S -71.6 161.0 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
 2019-05-15 ALA A:66 A:57 17.0 0.148 S -66.3 156.6 15.0 0.13 0.018 D:Q8WUF5:0.017
ALA B:66 B:57 18.0 0.157 S -66.5 156.6 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
 2020-11-18 ALA A:58 A:57 14.0 0.122 S -68.4 156.7 14.0 0.122 0.0 HOH
 3.122
 O
 O
5zqv 1 P62137 89.23 0.0 X-RAY
 2019-03-13 ALA A:57 A:57 15.0 0.13 S -75.7 157.8 12.0 0.104 0.026 E:Q16821:0.026
ALA B:57 B:57 9.0 0.078 S -69.0 161.7 NA NA NA
ALA C:57 C:57 16.0 0.139 S -72.7 160.1 16.0 0.139 0.0
ALA D:57 D:57 12.0 0.104 S -70.9 159.8 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
 2015-03-25 ALA D:57 D:57 10.0 0.087 S -73.1 157.3 NA NA NA
ALA F:57 F:57 11.0 0.096 S -73.2 157.3 NA NA NA
ALA H:57 H:57 11.0 0.096 S -73.2 157.3 NA NA NA
ALA J:57 J:57 11.0 0.096 S -73.1 157.4 11.0 0.096 0.0
ALA N:57 N:57 11.0 0.096 S -73.2 157.3 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
 2002-05-22 ALA A:57 A:57 17.0 0.148 S -80.6 162.9 17.0 0.148 0.0 HOH
 5.557
 N
 O
ALA B:57 B:57 19.0 0.165 S -87.6 164.9 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
 2001-08-15 ALA A:57 A:57 14.0 0.122 S -71.6 163.9 14.0 0.122 0.0 BME
HOH
 7.403
2.896
 CB
O
 S2
O
2bcd 1 P36873 89.06 0.0 X-RAY
 2006-01-17 ALA A:57 A:57 21.0 0.183 S -73.7 159.3 21.0 0.183 0.0 HOH
 7.869
 N
 O
2bdx 1 P36873 89.06 0.0 X-RAY
 2006-01-17 ALA A:57 A:57 20.0 0.174 S -70.2 158.1 20.0 0.174 0.0 HOH
 5.127
 N
 O
4ut2 1 P36873 89.06 0.0 X-RAY
 2015-07-22 ALA A:57 A:57 15.0 0.13 S -68.0 156.7 15.0 0.13 0.0 HOH
 4.947
 C
 O
ALA B:57 B:57 15.0 0.13 S -67.9 156.5 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
 2015-07-22 ALA A:57 A:57 16.0 0.139 S -67.6 159.3 16.0 0.139 0.0 HOH
 5.055
 N
 O
4ut3 2 P36873 89.06 0.0 X-RAY
 2015-07-22 ALA B:57 B:57 15.0 0.13 S -67.8 157.1 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
 2007-07-17 ALA A:63 A:57 16.0 0.139 S -75.5 156.8 12.0 0.104 0.035 B:Q9DCL8:0.035
 HOH
 5.327
 O
 O
ALA C:63 B:57 14.0 0.122 S -74.4 157.2 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
 2007-07-17 ALA A:63 A:57 12.0 0.104 S -72.4 159.0 7.0 0.061 0.043 B:Q9DCL8:0.043
 HOH
 6.008
 O
 O
ALA C:63 B:57 13.0 0.113 S -77.3 155.8 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
 2020-09-30 ALA A:56 D:56 15.0 0.13 S -73.5 162.1 15.0 0.13 0.0 HOH
 2.432
 O
 O
ALA B:56 A:56 14.0 0.122 S -71.5 159.2 NA NA NA
ALA C:56 F:56 16.0 0.139 S -62.1 162.7 NA NA NA
ALA D:56 I:56 17.0 0.148 S -71.6 160.0 NA NA NA
ALA E:56 L:56 16.0 0.139 S -66.6 161.4 NA NA NA
ALA F:56 O:56 17.0 0.148 S -76.3 163.6 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
 2012-10-31 ALA A:56 A:57 17.0 0.148 S -75.1 162.8 17.0 0.148 0.0 GOL
GOL
HOH
 4.497
9.930
5.681
 HA
N
HB1
 HO1
O2
O
ALA C:56 C:57 18.0 0.157 S -67.2 161.0 NA NA NA
ALA E:56 E:57 18.0 0.157 S -79.6 164.0 NA NA NA
ALA G:56 G:57 15.0 0.13 S -73.3 162.9 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
 2020-09-30 ALA A:56 A:57 16.0 0.139 S -71.2 158.8 16.0 0.139 0.0 HOH
 2.816
 O
 O
ALA C:56 B:57 15.0 0.13 S -73.4 160.9 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
 2019-09-18 ALA A:62 A:57 16.0 0.139 S -69.1 157.2 16.0 0.139 0.0
ALA B:62 B:57 17.0 0.148 S -67.4 159.0 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
 2019-09-18 ALA A:62 A:57 19.0 0.165 S -66.8 155.7 19.0 0.165 0.0 HOH
 6.571
 C
 O
3n5u 1 P62136 92.0 0.0 X-RAY
 2010-08-11 ALA A:57 A:57 12.0 0.104 S -62.8 157.2 12.0 0.104 0.0
ALA B:57 B:57 11.0 0.096 S -62.6 157.3 11.0 0.096 0.0
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 ALA A:56 A:57 11.0 0.096 S -67.1 156.0 11.0 0.096 0.0 HOH
 2.836
 O
 O
ALA C:56 B:57 13.0 0.113 S -61.2 157.7 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 ALA A:56 A:57 16.0 0.139 S -65.8 153.2 16.0 0.139 0.0 HOH
 2.821
 O
 O
ALA C:56 B:57 16.0 0.139 S -66.9 157.5 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
 2008-11-04 ALA A:56 A:57 17.0 0.148 S -82.2 156.5 17.0 0.148 0.0 HOH
 2.681
 O
 O
ALA B:56 B:57 18.0 0.157 S -85.9 160.2 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
 2008-11-04 ALA A:56 A:57 17.0 0.148 S -81.5 157.4 17.0 0.148 0.0 HOH
 2.795
 O
 O
ALA B:56 B:57 17.0 0.148 S -87.8 159.5 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
 2014-03-26 ALA A:56 A:57 18.0 0.157 S -83.6 159.2 18.0 0.157 0.0 HOH
 2.670
 O
 O
ALA B:56 B:57 18.0 0.157 S -92.6 160.2 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
 2014-03-26 ALA A:56 A:57 13.0 0.113 S -71.2 157.1 9.0 0.078 0.035 B:O55000:0.035
 GOL
HOH
 9.606
5.481
 N
N
 O1
O
4mp0 1 P62136 92.57 0.0 X-RAY
 2014-03-26 ALA A:56 A:57 15.0 0.13 S -73.6 157.9 10.0 0.087 0.043 C:O55000:0.043
 HOH
 4.873
 O
 O
ALA B:56 C:57 17.0 0.148 S -73.5 157.8 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
 2015-07-01 ALA A:56 A:57 16.0 0.139 S -69.7 156.9 14.0 0.122 0.017 B:O75807:0.017
 GOL
HOH
 9.390
5.234
 N
N
 O1
O
ALA C:56 C:57 17.0 0.148 S -70.5 156.7 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
 2016-10-05 ALA A:56 A:57 18.0 0.157 S -72.6 154.9 18.0 0.157 0.0 HOH
 5.754
 N
 O
ALA C:56 C:57 18.0 0.157 S -72.8 155.5 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
 2017-11-29 ALA A:56 A:57 20.0 0.174 S -79.1 158.6 20.0 0.174 0.0 HOH
 3.446
 C
 O
ALA B:56 B:57 20.0 0.174 S -77.6 157.9 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
 2019-01-23 ALA A:56 A:57 19.0 0.165 S -73.7 155.9 15.0 0.13 0.035 B:Q05C46:0.035
 HOH
 7.642
 N
 O
ALA C:56 C:57 17.0 0.148 S -80.1 154.9 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
 2019-01-23 ALA A:56 A:57 9.0 0.078 S -72.2 159.1 9.0 0.078 0.0 HOH
 4.971
 N
 O
6zee 1 P62136 92.57 0.0 X-RAY
 2020-09-30 ALA A:56 P:57 17.0 0.148 S -70.5 156.9 17.0 0.148 0.0 EDO
HOH
 5.606
3.141
 HB1
HB3
 H12
O
ALA B:56 Q:57 8.0 0.07 S -64.7 161.5 8.0 0.07 0.0 HOH
 4.811
 HB1
 O
ALA C:56 B:57 16.0 0.139 S -66.7 157.0 16.0 0.139 0.0 EDO
HOH
 5.796
6.573
 HA
H
 HO1
O
ALA D:56 A:57 15.0 0.13 S -68.7 155.2 15.0 0.13 0.0 EDO
HOH
 9.449
5.210
 N
HB1
 H22
O
ALA E:56 I:57 14.0 0.122 S -64.5 157.1 14.0 0.122 0.0 HOH
 6.160
 HA
 O
ALA F:56 K:57 15.0 0.13 S -67.7 155.5 15.0 0.13 0.0 HOH
 4.491
 H
 O
6zef 1 P62136 92.57 0.0 X-RAY
 2020-09-30 ALA A:56 A:57 16.0 0.139 S -76.1 160.5 16.0 0.139 0.0 EDO
EDO
HOH
 4.635
9.981
4.506
 N
N
O
 H11
H12
O
ALA B:56 B:57 13.0 0.113 S -73.7 155.2 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
 2016-10-05 ALA A:54 A:57 15.0 0.13 S -73.0 156.5 15.0 0.13 0.0 GOL
HOH
 6.100
2.643
 C
O
 O3
O
5j28 1 P36873 92.57 0.0 X-RAY
 2016-10-05 ALA A:54 A:57 17.0 0.148 S -71.2 158.9 17.0 0.148 0.0 HOH
 6.052
 O
 O
ALA B:54 B:57 11.0 0.096 S -69.8 159.8 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ALA A:56 A:57 17.0 0.148 S -82.9 160.0 17.0 0.148 0.0 HOH
 4.147
 CB
 O
ALA B:56 B:57 17.0 0.148 S -84.7 159.3 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ALA A:56 A:57 18.0 0.157 S -83.2 161.6 18.0 0.157 0.0 HOH
 3.612
 O
 O
ALA B:56 B:57 20.0 0.174 S -83.0 162.4 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ALA A:56 A:57 17.0 0.148 S -84.5 160.1 17.0 0.148 0.0 HOH
 3.167
 C
 O
ALA B:56 B:57 17.0 0.148 S -86.0 160.0 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ALA A:56 A:57 21.0 0.183 S -78.7 162.4 21.0 0.183 0.0 GOL
HOH
 4.837
3.568
 N
C
 O3
O
ALA B:56 B:57 18.0 0.157 S -81.5 159.5 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
 2019-03-13 ALA A:51 A:57 14.0 0.122 S -62.2 159.8 10.0 0.087 0.035 G:Q86XI6:0.035
ALA B:51 B:57 15.0 0.13 S -62.3 154.5 NA NA NA
ALA C:51 C:57 14.0 0.122 S -63.5 157.0 NA NA NA
ALA D:51 D:57 14.0 0.122 S -64.1 156.0 NA NA NA
ALA E:51 E:57 14.0 0.122 S -66.2 158.0 NA NA NA
ALA F:51 F:57 14.0 0.122 S -65.0 159.5 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
 2015-03-25 ALA A:52 A:57 10.0 0.087 S -74.3 157.2 10.0 0.087 0.0 HOH
 2.827
 O
 O
ALA C:52 C:57 10.0 0.087 S -74.4 156.9 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
 2015-03-25 ALA A:52 A:57 11.0 0.096 S -72.9 157.7 9.0 0.078 0.018 B:Q5SWA1:0.017
 HOH
 2.472
 O
 O
ALA C:52 C:57 15.0 0.13 S -70.2 154.5 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
 2015-03-25 ALA A:52 A:57 11.0 0.096 S -81.3 158.7 11.0 0.096 0.0 HOH
 4.725
 HA
 O
7nzm 2 P62139 92.52 0.0 EM
 2021-09-29 ALA B:51 B:57 13.0 0.113 S -83.0 158.9 13.0 0.113 0.0
1u32 1 P36873 90.78 0.0 X-RAY
 2004-08-17 ALA A:52 A:57 16.0 0.139 S -69.6 163.0 16.0 0.139 0.0 BME
HOH
 7.689
2.829
 CB
O
 S2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 ALA A:56 A:56 16.0 0.139 S -71.2 155.1
af-p62136-f1 1 P62136 88.79 0.0 ALA A:57 A:57 16.0 0.139 S -71.0 155.4
af-p36873-f1 1 P36873 89.06 0.0 ALA A:57 A:57 16.0 0.139 S -71.0 156.0