Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29001745 . C A CCDS33169.1:NM_002709.2:c.255aaC>aaA_NP_002700.1:p.85N>K Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
 2004-06-22 ASN A:88 A:86 50.0 0.312 -84.0 133.7 50.0 0.312 0.0 HOH
 2.882
 N
 O
1fjm 1 P08129 88.79 0.0 X-RAY
 1996-06-20 ASN A:86 A:86 40.0 0.25 -83.4 148.0 40.0 0.25 0.0 HOH
 2.664
 ND2
 O
ASN B:86 B:86 42.0 0.263 -84.2 143.3 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
 2012-09-19 ASN A:87 A:86 45.0 0.281 -94.7 150.4 45.0 0.281 0.0 HOH
 3.006
 N
 O
ASN B:87 B:86 42.0 0.263 -90.3 143.5 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
 2018-11-21 ASN A:87 A:86 36.0 0.225 -92.0 146.8 36.0 0.225 0.0 HOH
 3.137
 N
 O
6g0j 1 P62136 88.79 0.0 X-RAY
 2018-11-21 ASN A:87 A:86 38.0 0.237 -87.4 144.3 38.0 0.237 0.0 HOH
 3.172
 N
 O
3egg 1 P62136 89.26 0.0 X-RAY
 2010-03-23 ASN A:85 A:86 35.0 0.219 -85.4 140.2 35.0 0.219 0.0 GOL
HOH
 2.813
3.766
 N
CG
 O3
O
ASN B:85 B:86 37.0 0.231 -92.4 142.1 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
 2010-03-23 ASN A:85 A:86 34.0 0.212 -85.3 141.6 34.0 0.212 0.0 GOL
HOH
 2.886
2.755
 N
OD1
 O3
O
ASN B:85 B:86 37.0 0.231 -92.6 142.9 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
 2010-03-23 ASN A:85 A:86 32.0 0.2 -84.6 140.7 32.0 0.2 0.0 HOH
 2.709
 OD1
 O
ASN B:85 B:86 33.0 0.206 -91.4 138.0 33.0 0.206 0.0 HOH
 2.985
 N
 O
6ghm 1 P62136 89.26 0.0 X-RAY
 2019-02-27 ASN A:85 A:86 44.0 0.275 -84.2 143.5 44.0 0.275 0.0 GOL
HOH
 8.887
3.147
 ND2
N
 O2
O
ASN B:85 B:86 40.0 0.25 -78.9 150.8 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
 2019-05-15 ASN A:95 A:86 35.0 0.219 -92.3 142.7 21.0 0.131 0.088 D:Q8WUF5:0.087
ASN B:95 B:86 35.0 0.219 -90.7 143.5 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
 2020-11-18 ASN A:87 A:86 41.0 0.256 -96.1 143.4 41.0 0.256 0.0 HOH
 3.118
 N
 O
5zqv 1 P62137 89.23 0.0 X-RAY
 2019-03-13 ASN A:86 A:86 39.0 0.244 -66.9 144.5 39.0 0.244 0.0
ASN B:86 B:86 38.0 0.237 -64.1 155.5 NA NA NA
ASN C:86 C:86 42.0 0.263 -66.6 141.5 42.0 0.263 0.0
ASN D:86 D:86 39.0 0.244 -67.8 145.6 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
 2015-03-25 ASN D:86 D:86 42.0 0.263 -85.6 145.5 NA NA NA
ASN F:86 F:86 43.0 0.269 -85.5 145.6 NA NA NA
ASN H:86 H:86 42.0 0.263 -85.6 145.5 NA NA NA
ASN J:86 J:86 44.0 0.275 -85.5 145.5 44.0 0.275 0.0
ASN N:86 N:86 43.0 0.269 -85.6 145.5 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
 2002-05-22 ASN A:86 A:86 47.0 0.294 -86.2 142.6 47.0 0.294 0.0 HOH
 3.895
 CA
 O
ASN B:86 B:86 50.0 0.312 -89.0 148.1 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
 2001-08-15 ASN A:86 A:86 46.0 0.287 -85.8 145.2 46.0 0.287 0.0 HOH
 2.829
 N
 O
2bcd 1 P36873 89.06 0.0 X-RAY
 2006-01-17 ASN A:86 A:86 44.0 0.275 -88.6 145.2 44.0 0.275 0.0 HOH
 3.829
 CA
 O
2bdx 1 P36873 89.06 0.0 X-RAY
 2006-01-17 ASN A:86 A:86 39.0 0.244 -82.4 145.6 39.0 0.244 0.0 HOH
 2.950
 N
 O
4ut2 1 P36873 89.06 0.0 X-RAY
 2015-07-22 ASN A:86 A:86 35.0 0.219 -95.3 146.0 35.0 0.219 0.0 HOH
 2.914
 N
 O
ASN B:86 B:86 36.0 0.225 -95.5 144.8 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
 2015-07-22 ASN A:86 A:86 37.0 0.231 -90.1 141.1 37.0 0.231 0.0 HOH
 2.576
 OD1
 O
4ut3 2 P36873 89.06 0.0 X-RAY
 2015-07-22 ASN B:86 B:86 35.0 0.219 -88.8 142.8 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
 2007-07-17 ASN A:92 A:86 43.0 0.269 -92.7 141.9 24.0 0.15 0.119 B:Q9DCL8:0.119
 HOH
 3.368
 ND2
 O
ASN C:92 B:86 39.0 0.244 -93.1 143.8 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
 2007-07-17 ASN A:92 A:86 42.0 0.263 -90.4 143.6 22.0 0.138 0.125 B:Q9DCL8:0.125
 HOH
 3.010
 N
 O
ASN C:92 B:86 42.0 0.263 -89.5 141.3 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
 2020-09-30 ASN A:85 D:85 42.0 0.263 -85.8 148.0 42.0 0.263 0.0 HOH
 2.799
 HA
 O
ASN B:85 A:85 43.0 0.269 -83.7 148.8 NA NA NA
ASN C:85 F:85 40.0 0.25 -83.7 151.6 NA NA NA
ASN D:85 I:85 40.0 0.25 -85.6 147.6 NA NA NA
ASN E:85 L:85 42.0 0.263 -79.7 143.3 NA NA NA
ASN F:85 O:85 44.0 0.275 -84.9 146.5 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
 2012-10-31 ASN A:85 A:86 44.0 0.275 -80.3 144.5 44.0 0.275 0.0 GOL
GOL
HOH
 2.372
9.182
2.004
 ND2
HB3
H
 H11
HO2
O
ASN C:85 C:86 38.0 0.237 -87.0 146.7 NA NA NA
ASN E:85 E:86 46.0 0.287 -82.3 150.4 NA NA NA
ASN G:85 G:86 45.0 0.281 -79.8 146.2 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
 2020-09-30 ASN A:85 A:86 35.0 0.219 -90.5 143.0 35.0 0.219 0.0 HOH
 2.134
 HD21
 O
ASN C:85 B:86 38.0 0.237 -92.3 143.8 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
 2019-09-18 ASN A:91 A:86 41.0 0.256 -98.1 138.7 41.0 0.256 0.0
ASN B:91 B:86 39.0 0.244 -97.4 138.2 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
 2019-09-18 ASN A:91 A:86 40.0 0.25 -90.4 139.0 40.0 0.25 0.0 CL
HOH
 7.655
3.354
 OD1
N
 CL
O
3n5u 1 P62136 92.0 0.0 X-RAY
 2010-08-11 ASN A:86 A:86 53.0 0.331 -77.8 148.7 53.0 0.331 0.0
ASN B:86 B:86 53.0 0.331 -77.9 149.2 53.0 0.331 0.0
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 ASN A:85 A:86 37.0 0.231 -92.3 144.1 37.0 0.231 0.0 HOH
 2.005
 H
 O
ASN C:85 B:86 36.0 0.225 -99.1 142.2 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 ASN A:85 A:86 38.0 0.237 -83.2 147.1 38.0 0.237 0.0 HOH
 2.143
 H
 O
ASN C:85 B:86 39.0 0.244 -96.6 142.2 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
 2008-11-04 ASN A:85 A:86 45.0 0.281 -80.1 144.9 45.0 0.281 0.0 GOL
HOH
 8.504
2.726
 ND2
OD1
 O3
O
ASN B:85 B:86 42.0 0.263 -77.0 149.0 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
 2008-11-04 ASN A:85 A:86 46.0 0.287 -77.7 146.1 46.0 0.287 0.0 GOL
NA
HOH
 8.623
3.811
2.751
 ND2
CA
OD1
 O3
NA
O
ASN B:85 B:86 44.0 0.275 -74.0 144.8 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
 2014-03-26 ASN A:85 A:86 43.0 0.269 -77.1 148.2 43.0 0.269 0.0 HOH
 2.766
 OD1
 O
ASN B:85 B:86 42.0 0.263 -72.5 148.9 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
 2014-03-26 ASN A:85 A:86 43.0 0.269 -87.7 144.1 43.0 0.269 0.0 GOL
HOH
 7.411
2.361
 ND2
OD1
 O1
O
4mp0 1 P62136 92.57 0.0 X-RAY
 2014-03-26 ASN A:85 A:86 46.0 0.287 -81.4 142.9 46.0 0.287 0.0 GOL
HOH
 8.943
2.756
 ND2
N
 O1
O
ASN B:85 C:86 43.0 0.269 -80.8 143.2 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
 2015-07-01 ASN A:85 A:86 44.0 0.275 -80.9 146.1 44.0 0.275 0.0 GOL
HOH
 7.563
2.651
 ND2
ND2
 O1
O
ASN C:85 C:86 42.0 0.263 -81.7 146.8 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
 2016-10-05 ASN A:85 A:86 38.0 0.237 -82.2 147.7 38.0 0.237 0.0 HOH
 4.052
 CA
 O
ASN C:85 C:86 40.0 0.25 -82.3 147.3 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
 2017-11-29 ASN A:85 A:86 48.0 0.3 -80.0 142.4 48.0 0.3 0.0 DMS
HOH
 8.938
2.527
 ND2
ND2
 O
O
ASN B:85 B:86 41.0 0.256 -75.5 145.4 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
 2019-01-23 ASN A:85 A:86 40.0 0.25 -83.0 143.3 20.0 0.125 0.125 B:Q05C46:0.125
 HOH
 7.084
 OD1
 O
ASN C:85 C:86 41.0 0.256 -84.6 147.4 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
 2019-01-23 ASN A:85 A:86 39.0 0.244 -85.8 143.3 39.0 0.244 0.0 HOH
 2.814
 N
 O
6zee 1 P62136 92.57 0.0 X-RAY
 2020-09-30 ASN A:85 P:86 38.0 0.237 -85.3 147.0 38.0 0.237 0.0 EDO
EDO
HOH
 9.852
1.848
2.828
 HA
H
HA
 HO2
HO2
O
ASN B:85 Q:86 35.0 0.219 -86.6 144.5 35.0 0.219 0.0 HOH
 1.794
 H
 O
ASN C:85 B:86 37.0 0.231 -87.6 146.7 37.0 0.231 0.0 EDO
EDO
HOH
 9.837
1.800
2.716
 HA
H
HA
 H21
HO1
O
ASN D:85 A:86 40.0 0.25 -85.8 145.7 40.0 0.25 0.0 EDO
EDO
HOH
 9.864
8.509
2.159
 HA
HB3
H
 HO1
HO1
O
ASN E:85 I:86 40.0 0.25 -87.7 142.9 40.0 0.25 0.0 HOH
 2.451
 H
 O
ASN F:85 K:86 39.0 0.244 -87.8 145.5 39.0 0.244 0.0 EDO
HOH
 8.647
2.162
 HB3
H
 HO1
O
6zef 1 P62136 92.57 0.0 X-RAY
 2020-09-30 ASN A:85 A:86 38.0 0.237 -91.3 144.1 38.0 0.237 0.0 EDO
EDO
EDO
HOH
 2.337
9.729
9.993
2.301
 HB3
HB3
HA
H
 HO2
H12
H11
O
ASN B:85 B:86 38.0 0.237 -91.3 144.7 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
 2016-10-05 ASN A:83 A:86 42.0 0.263 -83.0 143.8 42.0 0.263 0.0 GOL
GOL
HOH
 9.856
3.000
2.783
 CG
N
OD1
 O1
O3
O
5j28 1 P36873 92.57 0.0 X-RAY
 2016-10-05 ASN A:83 A:86 42.0 0.263 -82.3 145.3 42.0 0.263 0.0 HOH
 3.045
 N
 O
ASN B:83 B:86 47.0 0.294 -77.7 146.8 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ASN A:85 A:86 41.0 0.256 -82.7 146.1 41.0 0.256 0.0 HOH
 2.770
 OD1
 O
ASN B:85 B:86 42.0 0.263 -79.7 146.0 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ASN A:85 A:86 45.0 0.281 -77.0 147.2 45.0 0.281 0.0 HOH
 2.609
 OD1
 O
ASN B:85 B:86 50.0 0.312 -82.2 145.5 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ASN A:85 A:86 44.0 0.275 -78.6 145.9 44.0 0.275 0.0 HOH
 2.460
 OD1
 O
ASN B:85 B:86 44.0 0.275 -78.1 146.0 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
 2019-09-18 ASN A:85 A:86 48.0 0.3 -82.1 146.9 48.0 0.3 0.0 GOL
GOL
HOH
 2.819
9.547
2.732
 ND2
ND2
OD1
 O3
O3
O
ASN B:85 B:86 49.0 0.306 -82.9 147.8 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
 2019-03-13 ASN A:80 A:86 37.0 0.231 -90.9 158.6 37.0 0.231 0.0
ASN B:80 B:86 41.0 0.256 -97.5 145.0 NA NA NA
ASN C:80 C:86 41.0 0.256 -74.7 145.0 NA NA NA
ASN D:80 D:86 42.0 0.263 -95.2 143.7 NA NA NA
ASN E:80 E:86 42.0 0.263 -86.0 163.2 NA NA NA
ASN F:80 F:86 43.0 0.269 -90.4 159.6 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
 2015-03-25 ASN A:81 A:86 42.0 0.263 -84.9 145.2 42.0 0.263 0.0 HOH
 2.602
 OD1
 O
ASN C:81 C:86 46.0 0.287 -81.0 145.9 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
 2015-03-25 ASN A:81 A:86 41.0 0.256 -83.3 144.6 41.0 0.256 0.0 HOH
 2.614
 OD1
 O
ASN C:81 C:86 42.0 0.263 -78.3 147.2 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
 2015-03-25 ASN A:81 A:86 42.0 0.263 -74.5 145.7 42.0 0.263 0.0 HOH
 2.049
 H
 O
7nzm 2 P62139 92.52 0.0 EM
 2021-09-29 ASN B:80 B:86 34.0 0.212 E -86.3 149.3 34.0 0.212 0.0
1u32 1 P36873 90.78 0.0 X-RAY
 2004-08-17 ASN A:81 A:86 39.0 0.244 -97.4 144.5 39.0 0.244 0.0 HOH
 3.138
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 ASN A:85 A:85 39.0 0.244 -77.7 143.9
af-p62136-f1 1 P62136 88.79 0.0 ASN A:86 A:86 39.0 0.244 -76.9 142.4
af-p36873-f1 1 P36873 89.06 0.0 ASN A:86 A:86 39.0 0.244 -76.2 143.0