Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29004703 . A C CCDS33169.1:NM_002709.2:c.515cAt>cCt_NP_002700.1:p.172H>P Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
 2004-06-22 HIS A:175 A:173 0.0 0.0 S -48.8 -69.3 0.0 0.0 0.0 MN
MN
HOH
 2.282
4.525
2.960
 NE2
NE2
N
 MN
MN
O
1fjm 1 P08129 88.79 0.0 X-RAY
 1996-06-20 HIS A:173 A:173 0.0 0.0 S -71.5 -56.3 0.0 0.0 0.0 MN
MN
HOH
 2.129
4.495
2.755
 NE2
NE2
N
 MN
MN
O
HIS B:173 B:173 0.0 0.0 S -70.4 -58.3 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
 2012-09-19 HIS A:174 A:173 0.0 0.0 S -68.8 -58.9 0.0 0.0 0.0 MN
HOH
 2.445
4.630
 NE2
NE2
 MN
O
HIS B:174 B:173 0.0 0.0 S -69.4 -54.4 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
 2018-11-21 HIS A:174 A:173 0.0 0.0 S -66.6 -56.9 0.0 0.0 0.0 PO4
FE
FE
MN
MN
HOH
 4.316
2.204
4.355
4.356
2.203
2.887
 NE2
NE2
NE2
NE2
NE2
N
 O2
FE
FE
MN
MN
O
6g0j 1 P62136 88.79 0.0 X-RAY
 2018-11-21 HIS A:174 A:173 0.0 0.0 S -68.0 -51.9 0.0 0.0 0.0 FE
FE
MN
MN
PO4
HOH
 2.144
4.357
4.339
2.157
4.219
2.759
 NE2
CE1
NE2
NE2
NE2
N
 FE
FE
MN
MN
O3
O
3egg 1 P62136 89.26 0.0 X-RAY
 2010-03-23 HIS A:172 A:173 0.0 0.0 S -68.3 -53.8 0.0 0.0 0.0 MN
MN
MES
HOH
 4.292
2.129
4.468
3.690
 NE2
NE2
NE2
NE2
 MN
MN
O3S
O
HIS B:172 B:173 0.0 0.0 S -73.1 -51.1 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
 2010-03-23 HIS A:172 A:173 0.0 0.0 S -68.3 -51.2 0.0 0.0 0.0 MN
MN
HOH
 4.455
2.180
2.711
 NE2
NE2
N
 MN
MN
O
HIS B:172 B:173 0.0 0.0 S -71.0 -54.6 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
 2010-03-23 HIS A:172 A:173 0.0 0.0 S -66.1 -56.1 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.440
2.230
4.480
2.799
 NE2
NE2
NE2
N
 MN
MN
O4
O
HIS B:172 B:173 0.0 0.0 S -69.2 -53.9 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.508
2.191
4.349
2.887
 CE1
NE2
NE2
N
 MN
MN
O3
O
6ghm 1 P62136 89.26 0.0 X-RAY
 2019-02-27 HIS A:172 A:173 0.0 0.0 S -70.0 -52.5 0.0 0.0 0.0 EDO
NHE
MN
MN
HOH
 9.812
4.671
4.450
2.194
2.753
 O
NE2
NE2
NE2
N
 O1
O1
MN
MN
O
HIS B:172 B:173 0.0 0.0 S -65.8 -58.4 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
 2019-05-15 HIS A:182 A:173 0.0 0.0 S -69.2 -51.9 0.0 0.0 0.0
HIS B:182 B:173 0.0 0.0 S -72.2 -52.8 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
 2020-11-18 HIS A:174 A:173 0.0 0.0 S -68.4 -56.8 0.0 0.0 0.0 MN
MN
FE
FE
PO4
HOH
 2.285
4.102
2.070
4.749
4.224
2.783
 NE2
NE2
NE2
NE2
NE2
N
 MN
MN
FE
FE
O3
O
5zqv 1 P62137 89.23 0.0 X-RAY
 2019-03-13 HIS A:173 A:173 0.0 0.0 S -74.6 -54.9 0.0 0.0 0.0 MN
FLC
 2.062
5.017
 NE2
NE2
 MN
OA2
HIS B:173 B:173 0.0 0.0 S -67.4 -49.7 NA NA NA
HIS C:173 C:173 0.0 0.0 S -71.4 -57.9 0.0 0.0 0.0 MN
FLC
 2.758
5.699
 NE2
NE2
 MN
OA1
HIS D:173 D:173 0.0 0.0 S -81.2 -45.9 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
 2015-03-25 HIS D:173 D:173 0.0 0.0 S -69.7 -53.9 NA NA NA
HIS F:173 F:173 0.0 0.0 S -69.7 -53.9 NA NA NA
HIS H:173 H:173 0.0 0.0 S -69.9 -53.9 NA NA NA
HIS J:173 J:173 0.0 0.0 S -69.7 -53.9 0.0 0.0 0.0 MN
MN
 4.332
2.276
 NE2
NE2
 MN
MN
HIS N:173 N:173 0.0 0.0 S -69.8 -53.9 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
 2002-05-22 HIS A:173 A:173 0.0 0.0 S -68.6 -63.9 0.0 0.0 0.0 MN
MN
CYU
HOH
 4.618
2.329
7.386
2.687
 NE2
NE2
NE2
N
 MN
MN
O6
O
HIS B:173 B:173 0.0 0.0 S -72.8 -59.3 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
 2001-08-15 HIS A:173 A:173 0.0 0.0 S -76.1 -57.7 0.0 0.0 0.0 MN
MN
OKA
HOH
 2.179
4.753
8.733
2.913
 NE2
NE2
NE2
N
 MN
MN
O2
O
2bcd 1 P36873 89.06 0.0 X-RAY
 2006-01-17 HIS A:173 A:173 0.0 0.0 S -73.9 -59.3 0.0 0.0 0.0 BME
MN
MN
HOH
 8.418
2.032
4.497
2.983
 CD2
NE2
NE2
N
 C2
MN
MN
O
2bdx 1 P36873 89.06 0.0 X-RAY
 2006-01-17 HIS A:173 A:173 0.0 0.0 S -72.9 -57.4 0.0 0.0 0.0 MN
MN
HOH
 2.070
4.508
2.745
 NE2
NE2
N
 MN
MN
O
4ut2 1 P36873 89.06 0.0 X-RAY
 2015-07-22 HIS A:173 A:173 0.0 0.0 S -65.2 -55.7 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.428
2.360
4.378
2.740
 NE2
NE2
NE2
N
 MN
MN
O3
O
HIS B:173 B:173 0.0 0.0 S -65.5 -55.2 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
 2015-07-22 HIS A:173 A:173 0.0 0.0 S -72.0 -53.5 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.554
2.237
4.398
2.869
 NE2
NE2
NE2
N
 MN
MN
O4
O
4ut3 2 P36873 89.06 0.0 X-RAY
 2015-07-22 HIS B:173 B:173 0.0 0.0 S -71.2 -54.5 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
 2007-07-17 HIS A:179 A:173 0.0 0.0 S -66.4 -49.7 0.0 0.0 0.0 HOH
 2.942
 N
 O
HIS C:179 B:173 0.0 0.0 S -72.7 -50.2 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
 2007-07-17 HIS A:179 A:173 0.0 0.0 S -66.3 -55.9 0.0 0.0 0.0 MN
HOH
 2.251
2.926
 NE2
N
 MN
O
HIS C:179 B:173 0.0 0.0 S -70.1 -56.1 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
 2020-09-30 HIS A:172 D:172 0.0 0.0 S -71.7 -56.5 0.0 0.0 0.0 MN
MN
HOH
 1.990
3.514
2.115
 NE2
HE1
H
 MN
MN
O
HIS B:172 A:172 0.0 0.0 S -66.1 -58.3 NA NA NA
HIS C:172 F:172 0.0 0.0 S -73.8 -58.0 NA NA NA
HIS D:172 I:172 0.0 0.0 S -71.2 -58.7 NA NA NA
HIS E:172 L:172 0.0 0.0 S -68.0 -62.5 NA NA NA
HIS F:172 O:172 0.0 0.0 S -70.7 -52.9 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
 2012-10-31 HIS A:172 A:173 0.0 0.0 S -78.9 -51.6 0.0 0.0 0.0 MN
MN
GOL
HOH
 2.112
3.781
9.002
2.145
 NE2
HE1
HD2
H
 MN
MN
HO2
O
HIS C:172 C:173 0.0 0.0 S -69.2 -56.7 NA NA NA
HIS E:172 E:173 0.0 0.0 S -70.6 -54.1 NA NA NA
HIS G:172 G:173 0.0 0.0 S -77.8 -52.9 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
 2020-09-30 HIS A:172 A:173 0.0 0.0 S -71.2 -53.6 0.0 0.0 0.0 MN
MN
PO4
HOH
 2.213
3.897
4.032
2.107
 NE2
HE1
NE2
H
 MN
MN
O4
O
HIS C:172 B:173 0.0 0.0 S -73.3 -51.3 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
 2019-09-18 HIS A:178 A:173 0.0 0.0 S -77.9 -54.6 0.0 0.0 0.0 PO4
FE
HOH
 4.520
2.350
3.779
 NE2
NE2
NE2
 O4
FE
O
HIS B:178 B:173 0.0 0.0 S -76.5 -55.3 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
 2019-09-18 HIS A:178 A:173 0.0 0.0 S -77.2 -58.5 0.0 0.0 0.0 PO4
MN
 4.376
2.228
 NE2
NE2
 O1
MN
3n5u 1 P62136 92.0 0.0 X-RAY
 2010-08-11 HIS A:173 A:173 0.0 0.0 S -66.2 -51.9 0.0 0.0 0.0 MN
MN
CL
 4.695
2.418
5.646
 CE1
NE2
NE2
 MN
MN
CL
HIS B:173 B:173 0.0 0.0 S -64.2 -52.6 0.0 0.0 0.0 MN
MN
CL
 4.626
2.436
5.438
 CE1
NE2
NE2
 MN
MN
CL
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 HIS A:172 A:173 0.0 0.0 S -70.9 -53.9 0.0 0.0 0.0 MN
MN
PO4
HOH
 2.213
3.904
3.956
2.059
 NE2
HE1
NE2
H
 MN
MN
O4
O
HIS C:172 B:173 0.0 0.0 S -72.1 -52.4 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 HIS A:172 A:173 0.0 0.0 S -72.0 -53.2 0.0 0.0 0.0 MN
MN
GOL
GOL
PO4
HOH
 2.231
3.869
9.796
9.361
3.981
2.100
 NE2
HE1
HD2
O
NE2
H
 MN
MN
H11
HO2
O4
O
HIS C:172 B:173 0.0 0.0 S -69.8 -52.4 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
 2008-11-04 HIS A:172 A:173 0.0 0.0 S -69.6 -54.3 0.0 0.0 0.0 MN
MN
HOH
 4.559
2.190
2.854
 NE2
NE2
N
 MN
MN
O
HIS B:172 B:173 0.0 0.0 S -73.0 -55.1 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
 2008-11-04 HIS A:172 A:173 0.0 0.0 S -72.4 -52.1 0.0 0.0 0.0 MN
MN
E7B
HOH
 4.546
2.207
6.833
2.929
 NE2
NE2
NE2
N
 MN
MN
O9
O
HIS B:172 B:173 0.0 0.0 S -68.2 -55.1 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
 2014-03-26 HIS A:172 A:173 0.0 0.0 S -72.4 -53.8 0.0 0.0 0.0 MN
MN
PO4
HOH
 2.208
4.423
4.390
2.815
 NE2
NE2
NE2
N
 MN
MN
O3
O
HIS B:172 B:173 0.0 0.0 S -72.6 -52.5 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
 2014-03-26 HIS A:172 A:173 0.0 0.0 S -65.2 -56.8 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.448
2.164
4.211
2.738
 NE2
NE2
NE2
N
 MN
MN
O4
O
4mp0 1 P62136 92.57 0.0 X-RAY
 2014-03-26 HIS A:172 A:173 0.0 0.0 S -70.7 -55.6 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.461
2.162
4.344
2.810
 CE1
NE2
NE2
N
 MN
MN
O3
O
HIS B:172 C:173 0.0 0.0 S -71.5 -55.9 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
 2015-07-01 HIS A:172 A:173 0.0 0.0 S -68.8 -51.8 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.154
1.969
4.049
2.806
 NE2
NE2
NE2
N
 MN
MN
O4
O
HIS C:172 C:173 0.0 0.0 S -67.2 -51.4 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
 2016-10-05 HIS A:172 A:173 0.0 0.0 S -78.0 -53.5 0.0 0.0 0.0 HOH
 2.647
 N
 O
HIS C:172 C:173 0.0 0.0 S -78.1 -53.4 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
 2017-11-29 HIS A:172 A:173 0.0 0.0 S -74.1 -60.1 0.0 0.0 0.0 MN
MN
BKM
HOH
 2.182
4.662
6.914
2.913
 NE2
NE2
NE2
N
 MN
MN
O37
O
HIS B:172 B:173 0.0 0.0 S -72.8 -57.4 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
 2019-01-23 HIS A:172 A:173 0.0 0.0 S -69.0 -58.8 0.0 0.0 0.0 MN
MN
PO4
HOH
 4.513
2.165
4.266
2.837
 CE1
NE2
NE2
N
 MN
MN
O4
O
HIS C:172 C:173 0.0 0.0 S -73.2 -61.1 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
 2019-01-23 HIS A:172 A:173 0.0 0.0 S -71.8 -51.0 0.0 0.0 0.0 HOH
 2.785
 N
 O
6zee 1 P62136 92.57 0.0 X-RAY
 2020-09-30 HIS A:172 P:173 0.0 0.0 S -66.9 -53.9 0.0 0.0 0.0 MN
MN
SO4
HOH
 2.276
3.772
4.300
2.234
 NE2
HE1
NE2
H
 MN
MN
O2
O
HIS B:172 Q:173 0.0 0.0 S -71.6 -51.4 0.0 0.0 0.0 MN
MN
SO4
HOH
 2.223
3.749
4.564
2.160
 NE2
HE1
NE2
H
 MN
MN
O4
O
HIS C:172 B:173 0.0 0.0 S -70.6 -54.4 0.0 0.0 0.0 MN
MN
EDO
EDO
EDO
SO4
GOL
HOH
 2.308
3.982
9.857
9.979
8.330
4.439
9.487
1.936
 NE2
HE1
O
O
NE2
NE2
HD2
H
 MN
MN
H21
HO1
H12
O1
O1
O
HIS D:172 A:173 0.0 0.0 S -68.8 -50.6 0.0 0.0 0.0 MN
MN
EDO
EDO
SO4
GOL
HOH
 2.191
3.833
6.482
7.665
4.283
9.492
2.112
 NE2
HE1
HE1
NE2
NE2
HD2
H
 MN
MN
HO1
H12
O4
H11
O
HIS E:172 I:173 0.0 0.0 S -75.1 -59.2 0.0 0.0 0.0 MN
MN
SO4
EDO
HOH
 2.288
4.176
4.316
9.690
2.034
 NE2
HE1
NE2
O
H
 MN
MN
O4
HO2
O
HIS F:172 K:173 0.0 0.0 S -74.9 -55.6 0.0 0.0 0.0 MN
MN
SO4
HOH
 2.177
3.998
4.368
2.048
 NE2
HE1
NE2
H
 MN
MN
O4
O
6zef 1 P62136 92.57 0.0 X-RAY
 2020-09-30 HIS A:172 A:173 0.0 0.0 S -71.8 -50.3 0.0 0.0 0.0 MN
MN
HOH
 3.420
7.238
2.135
 NE2
HE1
H
 MN
MN
O
HIS B:172 B:173 0.0 0.0 S -72.7 -48.6 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
 2016-10-05 HIS A:170 A:173 0.0 0.0 S -71.8 -49.3 0.0 0.0 0.0 MLI
HOH
 5.619
2.818
 NE2
N
 O8
O
5j28 1 P36873 92.57 0.0 X-RAY
 2016-10-05 HIS A:170 A:173 0.0 0.0 S -75.2 -56.5 0.0 0.0 0.0 MLI
HOH
 5.528
2.745
 NE2
N
 O8
O
HIS B:170 B:173 0.0 0.0 S -79.5 -56.5 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
 2019-09-18 HIS A:172 A:173 0.0 0.0 S -73.5 -52.8 0.0 0.0 0.0 MN
MN
HOH
 2.128
4.486
2.822
 NE2
NE2
N
 MN
MN
O
HIS B:172 B:173 0.0 0.0 S -72.3 -52.7 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
 2019-09-18 HIS A:172 A:173 0.0 0.0 S -74.5 -54.3 0.0 0.0 0.0 MN
HOH
 2.211
2.887
 NE2
N
 MN
O
HIS B:172 B:173 0.0 0.0 S -74.7 -54.9 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
 2019-09-18 HIS A:172 A:173 0.0 0.0 S -72.6 -51.8 0.0 0.0 0.0 MN
MN
PO4
HOH
 2.166
4.477
4.375
2.842
 NE2
NE2
NE2
N
 MN
MN
O2
O
HIS B:172 B:173 0.0 0.0 S -72.3 -52.7 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
 2019-09-18 HIS A:172 A:173 0.0 0.0 S -73.5 -53.7 0.0 0.0 0.0 MN
MN
HOH
 4.560
2.137
2.851
 CE1
NE2
N
 MN
MN
O
HIS B:172 B:173 0.0 0.0 S -73.3 -52.9 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
 2019-03-13 HIS A:167 A:173 0.0 0.0 S -68.7 -57.0 0.0 0.0 0.0 MN
MN
PO4
 2.452
4.252
4.975
 NE2
NE2
NE2
 MN
MN
O3
HIS B:167 B:173 0.0 0.0 S -69.0 -63.7 NA NA NA
HIS C:167 C:173 0.0 0.0 S -67.1 -56.5 NA NA NA
HIS D:167 D:173 0.0 0.0 S -73.4 -61.2 NA NA NA
HIS E:167 E:173 1.0 0.005 S -68.7 -59.5 NA NA NA
HIS F:167 F:173 1.0 0.005 S -71.8 -59.7 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
 2015-03-25 HIS A:168 A:173 0.0 0.0 S -69.8 -53.8 0.0 0.0 0.0 MN
HOH
 2.244
2.828
 NE2
N
 MN
O
HIS C:168 C:173 0.0 0.0 S -69.6 -55.6 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
 2015-03-25 HIS A:168 A:173 0.0 0.0 S -72.6 -52.2 0.0 0.0 0.0 MN
MN
HOH
 4.354
2.221
2.839
 NE2
NE2
N
 MN
MN
O
HIS C:168 C:173 0.0 0.0 S -71.0 -53.8 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
 2015-03-25 HIS A:168 A:173 0.0 0.0 S -73.6 -50.6 0.0 0.0 0.0 MN
HOH
 2.213
2.064
 NE2
H
 MN
O
7nzm 2 P62139 92.52 0.0 EM
 2021-09-29 HIS B:167 B:173 0.0 0.0 S -73.6 -54.1 0.0 0.0 0.0 MN
 1.993
 NE2
 MN
1u32 1 P36873 90.78 0.0 X-RAY
 2004-08-17 HIS A:168 A:173 0.0 0.0 S -78.9 -57.9 0.0 0.0 0.0 MN
MN
OKA
BME
HOH
 2.260
4.542
8.572
9.170
2.678
 NE2
NE2
NE2
CD2
N
 MN
MN
O2
C1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 HIS A:172 A:172 0.0 0.0 S -74.0 -60.4
af-p62136-f1 1 P62136 88.79 0.0 HIS A:173 A:173 0.0 0.0 S -73.2 -59.5
af-p36873-f1 1 P36873 89.06 0.0 HIS A:173 A:173 0.0 0.0 S -76.1 -60.2