Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29006800 . A C CCDS33169.1:NM_002709.2:c.548gAg>gCg_NP_002700.1:p.183E>A Homo sapiens protein phosphatase 1 catalytic subunit beta (PPP1CB), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1s70 1 P62140 100.0 0.0 X-RAY
 2004-06-22 GLU A:186 A:184 94.0 0.495 H -50.0 -26.0 94.0 0.495 0.0 HOH
 4.068
 OE1
 O
1fjm 1 P08129 88.79 0.0 X-RAY
 1996-06-20 GLU A:184 A:184 91.0 0.479 H -67.1 -23.6 91.0 0.479 0.0 HOH
 9.559
 O
 O
GLU B:184 B:184 110.0 0.579 H -58.6 -27.7 NA NA NA
4g9j 1 P62136 88.79 0.0 X-RAY
 2012-09-19 GLU A:185 A:184 102.0 0.537 H -57.9 -17.1 102.0 0.537 0.0 HOH
 4.766
 OE2
 O
GLU B:185 B:184 91.0 0.479 H -61.7 -31.8 NA NA NA
6g0i 1 P62136 88.79 0.0 X-RAY
 2018-11-21 GLU A:185 A:184 80.0 0.421 H -57.5 -32.5 80.0 0.421 0.0 HOH
 4.622
 N
 O
6g0j 1 P62136 88.79 0.0 X-RAY
 2018-11-21 GLU A:185 A:184 88.0 0.463 H -56.4 -33.8 88.0 0.463 0.0 HOH
 4.499
 N
 O
3egg 1 P62136 89.26 0.0 X-RAY
 2010-03-23 GLU A:183 A:184 102.0 0.537 H -62.2 -26.0 102.0 0.537 0.0 HOH
 2.704
 OE2
 O
GLU B:183 B:184 103.0 0.542 H -59.9 -28.9 NA NA NA
3egh 1 P62136 89.26 0.0 X-RAY
 2010-03-23 GLU A:183 A:184 101.0 0.532 H -61.0 -26.3 101.0 0.532 0.0 HOH
 2.464
 OE1
 O
GLU B:183 B:184 100.0 0.526 H -60.5 -29.7 NA NA NA
3hvq 1 P62136 89.26 0.0 X-RAY
 2010-03-23 GLU A:183 A:184 104.0 0.547 H -64.0 -24.9 104.0 0.547 0.0 HOH
 3.799
 N
 O
GLU B:183 B:184 101.0 0.532 H -57.4 -32.3 101.0 0.532 0.0 HOH
 1.981
 OE1
 O
6ghm 1 P62136 89.26 0.0 X-RAY
 2019-02-27 GLU A:183 A:184 72.0 0.379 H -66.0 -27.7 72.0 0.379 0.0 HOH
 3.310
 N
 O
GLU B:183 B:184 89.0 0.468 H -59.8 -24.7 NA NA NA
6dcx 1 P62136 88.79 0.0 X-RAY
 2019-05-15 GLU A:193 A:184 104.0 0.547 H -60.6 -28.4 104.0 0.547 0.0
GLU B:193 B:184 101.0 0.532 H -60.5 -28.0 NA NA NA
6zk6 1 P62136 88.48 0.0 X-RAY
 2020-11-18 GLU A:185 A:184 79.0 0.416 H -62.5 -29.4 79.0 0.416 0.0 HOH
 3.557
 N
 O
5zqv 1 P62137 89.23 0.0 X-RAY
 2019-03-13 GLU A:184 A:184 117.0 0.616 H -64.5 -27.6 117.0 0.616 0.0
GLU B:184 B:184 117.0 0.616 H -64.7 -25.7 NA NA NA
GLU C:184 C:184 112.0 0.589 H -63.6 -28.8 112.0 0.589 0.0
GLU D:184 D:184 112.0 0.589 H -60.7 -30.5 NA NA NA
4v0u 2 P63087 89.06 0.0 X-RAY
 2015-03-25 GLU D:184 D:184 74.0 0.389 H -57.4 -29.4 NA NA NA
GLU F:184 F:184 75.0 0.395 H -57.4 -29.4 NA NA NA
GLU H:184 H:184 75.0 0.395 H -57.5 -29.4 NA NA NA
GLU J:184 J:184 73.0 0.384 H -57.4 -29.5 73.0 0.384 0.0
GLU N:184 N:184 74.0 0.389 H -57.5 -29.4 NA NA NA
1it6 1 P36873 89.06 0.0 X-RAY
 2002-05-22 GLU A:184 A:184 84.0 0.442 H -59.4 -34.2 84.0 0.442 0.0 HOH
 5.607
 O
 O
GLU B:184 B:184 95.0 0.5 H -61.7 -34.1 NA NA NA
1jk7 1 P36873 89.06 0.0 X-RAY
 2001-08-15 GLU A:184 A:184 91.0 0.479 H -58.8 -30.3 91.0 0.479 0.0 HOH
 2.557
 OE1
 O
2bcd 1 P36873 89.06 0.0 X-RAY
 2006-01-17 GLU A:184 A:184 107.0 0.563 H -58.7 -33.6 107.0 0.563 0.0 MN
HOH
 4.057
2.651
 N
OE1
 MN
O
2bdx 1 P36873 89.06 0.0 X-RAY
 2006-01-17 GLU A:184 A:184 101.0 0.532 H -60.4 -32.9 101.0 0.532 0.0
4ut2 1 P36873 89.06 0.0 X-RAY
 2015-07-22 GLU A:184 A:184 79.0 0.416 H -59.2 -31.7 79.0 0.416 0.0 HOH
 3.397
 N
 O
GLU B:184 B:184 77.0 0.405 H -58.9 -31.7 NA NA NA
4ut3 1 P36873 89.06 0.0 X-RAY
 2015-07-22 GLU A:184 A:184 80.0 0.421 H -59.8 -35.9 80.0 0.421 0.0 HOH
 4.429
 N
 O
4ut3 2 P36873 89.06 0.0 X-RAY
 2015-07-22 GLU B:184 B:184 79.0 0.416 H -60.2 -36.2 NA NA NA
2o8a 1 P63088 89.52 0.0 X-RAY
 2007-07-17 GLU A:190 A:184 79.0 0.416 H -60.5 -31.2 79.0 0.416 0.0 HOH
 9.574
 N
 O
GLU C:190 B:184 76.0 0.4 H -62.0 -30.1 NA NA NA
2o8g 1 P63088 89.52 0.0 X-RAY
 2007-07-17 GLU A:190 A:184 80.0 0.421 H -61.3 -29.8 80.0 0.421 0.0 HOH
 4.679
 N
 O
GLU C:190 B:184 71.0 0.374 H -62.5 -28.0 NA NA NA
6zej 1 P62136,Q4VY12 86.42 0.0 X-RAY
 2020-09-30 GLU A:183 D:183 114.0 0.6 H -59.0 -24.6 114.0 0.6 0.0 HOH
 2.835
 H
 O
GLU B:183 A:183 86.0 0.453 H -60.5 -28.0 NA NA NA
GLU C:183 F:183 111.0 0.584 H -58.7 -25.6 NA NA NA
GLU D:183 I:183 116.0 0.611 H -64.1 -25.5 NA NA NA
GLU E:183 L:183 119.0 0.626 H -62.7 -24.2 NA NA NA
GLU F:183 O:183 89.0 0.468 H -59.7 -26.2 NA NA NA
3v4y 1 P62136 92.05 0.0 X-RAY
 2012-10-31 GLU A:183 A:184 72.0 0.379 H -58.5 -31.7 59.0 0.311 0.068 B:Q12972:0.068
 HOH
 2.125
 H
 O
GLU C:183 C:184 76.0 0.4 H -60.3 -28.4 NA NA NA
GLU E:183 E:184 75.0 0.395 H -56.5 -35.2 NA NA NA
GLU G:183 G:184 73.0 0.384 H -60.6 -28.7 NA NA NA
6zeh 1 P62136,Q13813 92.28 0.0 X-RAY
 2020-09-30 GLU A:183 A:184 83.0 0.437 H -59.9 -29.2 83.0 0.437 0.0 HOH
 3.910
 H
 O
GLU C:183 B:184 106.0 0.558 H -63.9 -23.9 NA NA NA
6obn 1 P62136 92.0 0.0 X-RAY
 2019-09-18 GLU A:189 A:184 81.0 0.426 H -60.4 -35.7 81.0 0.426 0.0 CL
HOH
 5.323
7.572
 N
OE1
 CL
O
GLU B:189 B:184 87.0 0.458 H -57.6 -35.9 NA NA NA
6obp 1 P62136 92.0 0.0 X-RAY
 2019-09-18 GLU A:189 A:184 98.0 0.516 H -67.9 -26.2 98.0 0.516 0.0 CL
HOH
 5.614
7.210
 N
OE1
 CL
O
3n5u 1 P62136 92.0 0.0 X-RAY
 2010-08-11 GLU A:184 A:184 87.0 0.458 H -85.2 -25.8 87.0 0.458 0.0
GLU B:184 B:184 88.0 0.463 H -84.6 -25.2 88.0 0.463 0.0
6zeg 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 GLU A:183 A:184 82.0 0.432 H -59.7 -28.9 82.0 0.432 0.0 EDO
HOH
 7.126
3.364
 O
OE1
 HO2
O
GLU C:183 B:184 98.0 0.516 H -60.0 -29.0 NA NA NA
6zei 1 P62136,Q9UQB8 92.28 0.0 X-RAY
 2020-09-30 GLU A:183 A:184 99.0 0.521 H -61.5 -28.0 99.0 0.521 0.0 HOH
 2.584
 OE1
 O
GLU C:183 B:184 105.0 0.553 H -60.9 -26.3 NA NA NA
3e7a 1 P62136 92.57 0.0 X-RAY
 2008-11-04 GLU A:183 A:184 86.0 0.453 H -56.9 -30.5 86.0 0.453 0.0 HOH
 2.606
 OE2
 O
GLU B:183 B:184 85.0 0.447 H -59.1 -26.8 NA NA NA
3e7b 1 P62136 92.57 0.0 X-RAY
 2008-11-04 GLU A:183 A:184 82.0 0.432 H -58.7 -29.4 82.0 0.432 0.0 HOH
 3.381
 N
 O
GLU B:183 B:184 111.0 0.584 H -61.5 -26.1 NA NA NA
4mov 1 P62136 92.57 0.0 X-RAY
 2014-03-26 GLU A:183 A:184 86.0 0.453 H -59.3 -31.2 86.0 0.453 0.0 HOH
 3.652
 N
 O
GLU B:183 B:184 109.0 0.574 H -59.9 -28.3 NA NA NA
4moy 1 P62136 92.57 0.0 X-RAY
 2014-03-26 GLU A:183 A:184 110.0 0.579 H -59.6 -31.4 110.0 0.579 0.0 HOH
 4.710
 N
 O
4mp0 1 P62136 92.57 0.0 X-RAY
 2014-03-26 GLU A:183 A:184 106.0 0.558 H -65.7 -26.6 106.0 0.558 0.0 HOH
 5.318
 O
 O
GLU B:183 C:184 122.0 0.642 H -67.0 -26.7 NA NA NA
4xpn 1 P62136 92.57 0.0 X-RAY
 2015-07-01 GLU A:183 A:184 82.0 0.432 H -64.6 -25.5 82.0 0.432 0.0 HOH
 3.509
 N
 O
GLU C:183 C:184 110.0 0.579 H -65.4 -24.1 NA NA NA
5ioh 1 P62136 92.57 0.0 X-RAY
 2016-10-05 GLU A:183 A:184 111.0 0.584 H -61.2 -30.6 111.0 0.584 0.0 HOH
 5.223
 O
 O
GLU C:183 C:184 83.0 0.437 H -62.5 -30.7 NA NA NA
6alz 1 P62136 92.57 0.0 X-RAY
 2017-11-29 GLU A:183 A:184 88.0 0.463 H -66.5 -25.8 88.0 0.463 0.0 HOH
 4.639
 N
 O
GLU B:183 B:184 78.0 0.411 H -64.1 -25.3 NA NA NA
6czo 1 P62136 92.57 0.0 X-RAY
 2019-01-23 GLU A:183 A:184 94.0 0.495 H -71.3 -23.6 94.0 0.495 0.0 HOH
 5.263
 O
 O
GLU C:183 C:184 128.0 0.674 H -77.5 -10.9 NA NA NA
6dno 1 P62136 92.57 0.0 X-RAY
 2019-01-23 GLU A:183 A:184 68.0 0.358 H -59.6 -28.7 68.0 0.358 0.0 HOH
 3.462
 CG
 O
6zee 1 P62136 92.57 0.0 X-RAY
 2020-09-30 GLU A:183 P:184 105.0 0.553 H -59.0 -32.2 105.0 0.553 0.0 EDO
EDO
HOH
 7.794
2.486
5.532
 O
HG2
O
 H12
HO1
O
GLU B:183 Q:184 80.0 0.421 H -56.0 -27.4 80.0 0.421 0.0 EDO
HOH
 2.630
6.445
 H
OE2
 O1
O
GLU C:183 B:184 112.0 0.589 H -59.8 -28.5 112.0 0.589 0.0 EDO
HOH
 2.633
2.236
 HB2
OE1
 HO1
O
GLU D:183 A:184 81.0 0.426 H -59.3 -25.6 81.0 0.426 0.0 EDO
16P
EDO
HOH
 2.035
6.304
9.170
3.610
 HG2
HA
OE1
OE2
 HO1
H42
H12
O
GLU E:183 I:184 115.0 0.605 H -61.2 -24.3 115.0 0.605 0.0 HOH
 3.078
 H
 O
GLU F:183 K:184 120.0 0.632 H -61.3 -28.1 120.0 0.632 0.0 GOL
HOH
 8.055
3.263
 O
HG2
 HO3
O
6zef 1 P62136 92.57 0.0 X-RAY
 2020-09-30 GLU A:183 A:184 102.0 0.537 H -59.6 -25.9 102.0 0.537 0.0 EDO
HOH
 6.691
2.535
 HA
OE2
 HO1
O
GLU B:183 B:184 100.0 0.526 H -58.9 -26.2 NA NA NA
5inb 1 P36873 92.57 0.0 X-RAY
 2016-10-05 GLU A:181 A:184 80.0 0.421 H -61.4 -25.8 80.0 0.421 0.0 NA
HOH
 8.228
2.359
 N
OE2
 NA
O
5j28 1 P36873 92.57 0.0 X-RAY
 2016-10-05 GLU A:181 A:184 128.0 0.674 H -57.4 -29.5 128.0 0.674 0.0 NA
HOH
 7.948
4.504
 N
N
 NA
O
GLU B:181 B:184 25.0 NA H -58.7 -23.3 NA NA NA
6obr 1 P62136 92.23 0.0 X-RAY
 2019-09-18 GLU A:183 A:184 82.0 0.432 H -63.7 -27.3 82.0 0.432 0.0 HOH
 4.134
 CB
 O
GLU B:183 B:184 101.0 0.532 H -64.3 -24.4 NA NA NA
6obq 1 P62136 92.23 0.0 X-RAY
 2019-09-18 GLU A:183 A:184 112.0 0.589 H -64.7 -27.2 112.0 0.589 0.0 HOH
 7.377
 OE1
 O
GLU B:183 B:184 90.0 0.474 H -63.3 -26.0 NA NA NA
6obs 1 P62136 92.23 0.0 X-RAY
 2019-09-18 GLU A:183 A:184 93.0 0.489 H -60.9 -27.4 93.0 0.489 0.0 HOH
 2.670
 OE2
 O
GLU B:183 B:184 86.0 0.453 H -61.1 -25.0 NA NA NA
6obu 1 P62136 92.23 0.0 X-RAY
 2019-09-18 GLU A:183 A:184 90.0 0.474 H -65.7 -26.3 90.0 0.474 0.0 HOH
 4.460
 N
 O
GLU B:183 B:184 103.0 0.542 H -65.0 -24.7 NA NA NA
5zt0 1 P62137 92.52 0.0 X-RAY
 2019-03-13 GLU A:178 A:184 96.0 0.505 H -67.7 -26.6 96.0 0.505 0.0
GLU B:178 B:184 112.0 0.589 H -65.6 -25.7 NA NA NA
GLU C:178 C:184 100.0 0.526 H -66.0 -29.2 NA NA NA
GLU D:178 D:184 100.0 0.526 H -60.0 -29.7 NA NA NA
GLU E:178 E:184 97.0 0.511 H -64.7 -30.2 NA NA NA
GLU F:178 F:184 85.0 0.447 H -66.7 -25.8 NA NA NA
4v0v 1 P63087 92.52 0.0 X-RAY
 2015-03-25 GLU A:179 A:184 75.0 0.395 H -58.3 -29.0 75.0 0.395 0.0 HOH
 3.137
 OE2
 O
GLU C:179 C:184 111.0 0.584 H -65.4 -25.6 NA NA NA
4v0w 1 P63087 92.52 0.0 X-RAY
 2015-03-25 GLU A:179 A:184 73.0 0.384 H -56.1 -31.2 73.0 0.384 0.0 HOH
 2.411
 OE2
 O
GLU C:179 C:184 105.0 0.553 H -60.4 -27.4 NA NA NA
4v0x 1 P63087 92.52 0.0 X-RAY
 2015-03-25 GLU A:179 A:184 86.0 0.453 H -62.2 -27.2 86.0 0.453 0.0 HOH
 8.902
 O
 O
7nzm 2 P62139 92.52 0.0 EM
 2021-09-29 GLU B:178 B:184 89.0 0.468 H -59.9 -30.7 89.0 0.468 0.0
1u32 1 P36873 90.78 0.0 X-RAY
 2004-08-17 GLU A:179 A:184 89.0 0.468 H -63.5 -37.1 89.0 0.468 0.0 HOH
 3.303
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p62140-f1 1 P62140 100.0 0.0 GLU A:183 A:183 81.0 0.426 H -58.6 -28.1
af-p62136-f1 1 P62136 88.79 0.0 GLU A:184 A:184 78.0 0.411 H -58.5 -28.3
af-p36873-f1 1 P36873 89.06 0.0 GLU A:184 A:184 71.0 0.374 H -61.9 -27.4