Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29455225 . C A CCDS33172.1:NM_004304.4:c.2577gaG>gaT_NP_004295.2:p.859E>D Homo sapiens anaplastic lymphoma receptor tyrosine kinase (ALK), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7nx3 1 Q9UM73 100.0 0.0 X-RAY
 2021-10-27 GLU A:212 A:859 66.0 0.347 -71.8 143.0 66.0 0.347 0.0
GLU F:212 F:859 71.0 0.374 -74.9 140.4 NA NA NA
7nx4 1 Q9UM73 100.0 0.0 X-RAY
 2021-10-27 GLU A:212 A:859 33.0 0.174 -108.6 110.7 33.0 0.174 0.0 NAG
NI
 5.970
2.736
 O
OE2
 O6
NI
7n00 1 Q9UM73 100.0 0.0 EM
 2021-11-24 GLU A:213 A:859 70.0 0.368 -72.1 121.2 34.0 0.179 0.189 C:Q6UX46:0.189
GLU B:213 C:859 72.0 0.379 -71.7 122.7 36.0 0.189 0.19 D:Q6UX46:0.189
7mzw 1 Q9UM73 100.0 0.0 NMR
 2021-12-08 GLU A:187 A:859 71.0 0.374 -61.5 116.0 71.0 0.374 0.0
7ls0 1 Q9UM73,Q6UX46 99.72 0.0 X-RAY
 2021-11-24 GLU A:197 A:859 22.0 0.116 -88.5 125.1 22.0 0.116 0.0
GLU B:197 B:859 37.0 0.195 -75.1 140.2 NA NA NA
GLU C:197 C:859 34.0 0.179 -73.4 140.4 34.0 0.179 0.0
GLU D:197 D:859 35.0 0.184 -110.8 130.9 NA NA NA
7mzy 1 Q9UM73 100.0 0.0 X-RAY
 2021-11-24 GLU A:188 A:859 65.0 0.342 -81.9 143.2 11.0 0.058 0.284 B:Q9UM73:0.284
 HOH
 3.021
 O
 O
GLU B:188 B:859 68.0 0.358 -68.9 130.6 68.0 0.358 0.0 HOH
 3.312
 OE2
 O
7lrz 1 Q9UM73 99.68 0.0 X-RAY
 2021-11-24 GLU A:184 A:859 74.0 0.389 -72.7 133.3 74.0 0.389 0.0 HOH
 3.544
 CA
 O
7nwz 2 Q9UM73 98.55 0.0 X-RAY
 2021-10-27 GLU B:212 F:859 75.0 0.395 -83.2 166.9 75.0 0.395 0.0
GLU C:212 E:859 76.0 0.4 -82.9 167.4 32.0 0.168 0.232 A:Q6UX46:0.232
GLU D:212 B:859 72.0 0.379 -82.0 166.6 NA NA NA
GLU E:212 A:859 79.0 0.416 -80.3 165.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9um73-f1 1 Q9UM73 100.0 0.0 GLU A:859 A:859 68.0 0.358 -64.6 122.4