Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29462691 . G A CCDS33172.1:NM_004304.4:c.2210tCg>tTg_NP_004295.2:p.737S>L Homo sapiens anaplastic lymphoma receptor tyrosine kinase (ALK), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7nx3 1 Q9UM73 100.0 0.0 X-RAY
 2021-10-27 SER A:90 A:737 13.0 0.113 E -117.0 115.5 13.0 0.113 0.0
SER F:90 F:737 21.0 0.183 E -115.3 115.4 NA NA NA
7nx4 1 Q9UM73 100.0 0.0 X-RAY
 2021-10-27 SER A:90 A:737 8.0 0.07 E -114.3 111.9 8.0 0.07 0.0
7n00 1 Q9UM73 100.0 0.0 EM
 2021-11-24 SER A:91 A:737 4.0 0.035 E -110.6 112.7 2.0 0.017 0.018 C:Q6UX46:0.017
SER B:91 C:737 4.0 0.035 E -109.3 114.9 2.0 0.017 0.018 D:Q6UX46:0.017
7mzw 1 Q9UM73 100.0 0.0 NMR
 2021-12-08 SER A:65 A:737 8.0 0.07 E -110.1 103.5 8.0 0.07 0.0
7ls0 1 Q9UM73,Q6UX46 99.72 0.0 X-RAY
 2021-11-24 SER A:75 A:737 12.0 0.104 E -111.5 105.6 12.0 0.104 0.0
SER B:75 B:737 6.0 0.052 E -115.2 103.4 NA NA NA
SER C:75 C:737 11.0 0.096 E -106.5 108.2 11.0 0.096 0.0
SER D:75 D:737 9.0 0.078 E -104.2 112.7 NA NA NA
7mzy 1 Q9UM73 100.0 0.0 X-RAY
 2021-11-24 SER A:66 A:737 18.0 0.157 E -115.1 134.3 18.0 0.157 0.0 HOH
 3.638
 CB
 O
SER B:66 B:737 12.0 0.104 E -111.7 120.8 10.0 0.087 0.017 A:Q9UM73:0.017
 HOH
 2.764
 OG
 O
7lrz 1 Q9UM73 99.68 0.0 X-RAY
 2021-11-24 SER A:62 A:737 14.0 0.122 E -102.6 116.1 14.0 0.122 0.0 HOH
 2.875
 OG
 O
7nwz 2 Q9UM73 98.55 0.0 X-RAY
 2021-10-27 SER B:90 F:737 7.0 0.061 E -106.1 108.0 0.0 0.0 0.061 A:Q6UX46:0.061
SER C:90 E:737 0.0 0.0 E -104.6 108.1 0.0 0.0 0.0
SER D:90 B:737 10.0 0.087 E -105.5 107.3 NA NA NA
SER E:90 A:737 5.0 0.043 E -105.6 108.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9um73-f1 1 Q9UM73 100.0 0.0 SER A:737 A:737 12.0 0.104 E -103.7 132.1