Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 29474026 | . | C | A | CCDS33172.1:NM_004304.4:c.2149Gag>Tag_NP_004295.2:p.717E>* | Homo sapiens anaplastic lymphoma receptor tyrosine kinase (ALK), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7nx3 | 1 | Q9UM73 | 100.0 | 0.0 |
X-RAY |
2021-10-27 | GLU | A:70 | A:717 | 165.0 | 0.868 | S | -162.9 | 155.7 | 165.0 | 0.868 | 0.0 | ||||||
GLU | F:70 | F:717 | 165.0 | 0.868 | S | -159.2 | 153.7 | NA | NA | NA | |||||||||||||
7nx4 | 1 | Q9UM73 | 100.0 | 0.0 |
X-RAY |
2021-10-27 | GLU | A:70 | A:717 | 162.0 | 0.853 | S | -137.6 | 153.3 | 162.0 | 0.853 | 0.0 | ||||||
7n00 | 1 | Q9UM73 | 100.0 | 0.0 |
EM |
2021-11-24 | GLU | A:71 | A:717 | 133.0 | 0.7 | S | -150.9 | 158.1 | 133.0 | 0.7 | 0.0 | ||||||
GLU | B:71 | C:717 | 129.0 | 0.679 | S | -149.7 | 158.0 | 129.0 | 0.679 | 0.0 | |||||||||||||
7mzw | 1 | Q9UM73 | 100.0 | 0.0 |
NMR |
2021-12-08 | GLU | A:45 | A:717 | 148.0 | 0.779 | S | -143.3 | 174.2 | 148.0 | 0.779 | 0.0 | ||||||
7ls0 | 1 | Q9UM73,Q6UX46 | 99.72 | 0.0 |
X-RAY |
2021-11-24 | GLU | A:55 | A:717 | 150.0 | 0.789 | S | -148.0 | -179.1 | 150.0 | 0.789 | 0.0 |
CIT |
7.194 |
C |
O4 |
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GLU | B:55 | B:717 | 145.0 | 0.763 | S | -153.4 | 156.9 | NA | NA | NA | |||||||||||||
GLU | C:55 | C:717 | 131.0 | 0.689 | S | -153.1 | 161.5 | 131.0 | 0.689 | 0.0 | |||||||||||||
GLU | D:55 | D:717 | 100.0 | 0.526 | S | -60.1 | 176.7 | NA | NA | NA | |||||||||||||
7mzy | 1 | Q9UM73 | 100.0 | 0.0 |
X-RAY |
2021-11-24 | GLU | A:46 | A:717 | 159.0 | 0.837 | S | -144.9 | 160.7 | 159.0 | 0.837 | 0.0 |
HOH |
2.702 |
OE2 |
O |
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GLU | B:46 | B:717 | 154.0 | 0.811 | S | -160.3 | 168.8 | 154.0 | 0.811 | 0.0 |
HOH |
2.547 |
O |
O |
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7lrz | 1 | Q9UM73 | 99.68 | 0.0 |
X-RAY |
2021-11-24 | GLU | A:42 | A:717 | 133.0 | 0.7 | S | -150.0 | 155.6 | 133.0 | 0.7 | 0.0 |
HOH |
2.561 |
O |
O |
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7nwz | 2 | Q9UM73 | 98.55 | 0.0 |
X-RAY |
2021-10-27 | GLU | B:70 | F:717 | 154.0 | 0.811 | S | -163.0 | 158.9 | 154.0 | 0.811 | 0.0 | ||||||
GLU | C:70 | E:717 | 146.0 | 0.768 | S | -161.2 | 152.8 | 146.0 | 0.768 | 0.0 | |||||||||||||
GLU | D:70 | B:717 | 143.0 | 0.753 | S | -161.8 | 160.7 | NA | NA | NA | |||||||||||||
GLU | E:70 | A:717 | 154.0 | 0.811 | S | -162.5 | 157.2 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9um73-f1 | 1 | Q9UM73 | 100.0 | 0.0 | GLU | A:717 | A:717 | 158.0 | 0.832 | S | -133.4 | 157.9 |