Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 29474048 | . | G | A | CCDS33172.1:NM_004304.4:c.2127aaC>aaT_NP_004295.2:p.709N>N | Homo sapiens anaplastic lymphoma receptor tyrosine kinase (ALK), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
7nx3 | 1 | Q9UM73 | 100.0 | 0.0 |
X-RAY |
2021-10-27 | ASN | A:62 | A:709 | 107.0 | 0.669 | S | -82.4 | -12.5 | 76.0 | 0.475 | 0.194 |
C:None:0.194 |
NAG |
1.461 |
ND2 |
C1 |
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ASN | F:62 | F:709 | 100.0 | 0.625 | S | -94.1 | 67.1 | NA | NA | NA | |||||||||||||
7nx4 | 1 | Q9UM73 | 100.0 | 0.0 |
X-RAY |
2021-10-27 | ASN | A:62 | A:709 | 117.0 | 0.731 | S | -84.7 | 65.0 | 117.0 | 0.731 | 0.0 | ||||||
7n00 | 1 | Q9UM73 | 100.0 | 0.0 |
EM |
2021-11-24 | ASN | A:63 | A:709 | 88.0 | 0.55 | S | -85.4 | 6.2 | 88.0 | 0.55 | 0.0 | ||||||
ASN | B:63 | C:709 | 89.0 | 0.556 | S | -85.4 | 6.1 | 89.0 | 0.556 | 0.0 | |||||||||||||
7mzw | 1 | Q9UM73 | 100.0 | 0.0 |
NMR |
2021-12-08 | ASN | A:37 | A:709 | 94.0 | 0.588 | S | -77.4 | -0.8 | 94.0 | 0.588 | 0.0 | ||||||
7ls0 | 1 | Q9UM73,Q6UX46 | 99.72 | 0.0 |
X-RAY |
2021-11-24 | ASN | A:47 | A:709 | 146.0 | 0.912 | S | -77.8 | 63.8 | 146.0 | 0.912 | 0.0 | ||||||
ASN | B:47 | B:709 | 138.0 | 0.863 | S | -74.6 | -25.9 | NA | NA | NA | |||||||||||||
ASN | C:47 | C:709 | 155.0 | 0.969 | S | -80.9 | 34.5 | 155.0 | 0.969 | 0.0 | |||||||||||||
ASN | D:47 | D:709 | 150.0 | 0.938 | T | -98.5 | 50.4 | NA | NA | NA | |||||||||||||
7mzy | 1 | Q9UM73 | 100.0 | 0.0 |
X-RAY |
2021-11-24 | ASN | A:38 | A:709 | 121.0 | 0.756 | S | -86.5 | 12.9 | 121.0 | 0.756 | 0.0 |
HOH |
2.800 |
N |
O |
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ASN | B:38 | B:709 | 86.0 | 0.537 | S | -87.6 | 10.8 | 86.0 | 0.537 | 0.0 |
HOH |
2.780 |
OD1 |
O |
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7lrz | 1 | Q9UM73 | 99.68 | 0.0 |
X-RAY |
2021-11-24 | ASN | A:34 | A:709 | 165.0 | 1.0 | T | -94.0 | 53.6 | 165.0 | 1.0 | 0.0 |
HOH |
3.444 |
O |
O |
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7nwz | 2 | Q9UM73 | 98.55 | 0.0 |
X-RAY |
2021-10-27 | ASN | B:62 | F:709 | 125.0 | 0.781 | S | -92.5 | 18.1 | 125.0 | 0.781 | 0.0 | ||||||
ASN | C:62 | E:709 | 150.0 | 0.938 | S | -91.7 | 18.3 | 150.0 | 0.938 | 0.0 | |||||||||||||
ASN | D:62 | B:709 | 133.0 | 0.831 | S | -90.6 | 20.8 | NA | NA | NA | |||||||||||||
ASN | E:62 | A:709 | 121.0 | 0.756 | S | -92.2 | 17.9 | NA | NA | NA |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-q9um73-f1 | 1 | Q9UM73 | 100.0 | 0.0 | ASN | A:709 | A:709 | 131.0 | 0.819 | S | -76.8 | 17.4 |