Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 29474122 . A C CCDS33172.1:NM_004304.4:c.2053Ttc>Gtc_NP_004295.2:p.685F>V Homo sapiens anaplastic lymphoma receptor tyrosine kinase (ALK), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
7nx3 1 Q9UM73 100.0 0.0 X-RAY
 2021-10-27 PHE A:38 A:685 0.0 0.0 E -93.8 129.9 0.0 0.0 0.0
PHE F:38 F:685 0.0 0.0 E -94.3 130.8 NA NA NA
7nx4 1 Q9UM73 100.0 0.0 X-RAY
 2021-10-27 PHE A:38 A:685 0.0 0.0 E -103.5 131.5 0.0 0.0 0.0
7n00 1 Q9UM73 100.0 0.0 EM
 2021-11-24 PHE A:39 A:685 0.0 0.0 E -103.3 125.9 0.0 0.0 0.0
PHE B:39 C:685 0.0 0.0 E -103.9 125.8 0.0 0.0 0.0
7mzw 1 Q9UM73 100.0 0.0 NMR
 2021-12-08 PHE A:13 A:685 0.0 0.0 E -86.0 114.1 0.0 0.0 0.0
7ls0 1 Q9UM73,Q6UX46 99.72 0.0 X-RAY
 2021-11-24 PHE A:23 A:685 0.0 0.0 E -106.7 119.5 0.0 0.0 0.0
PHE B:23 B:685 0.0 0.0 E -102.5 127.1 NA NA NA
PHE C:23 C:685 0.0 0.0 E -96.7 122.6 0.0 0.0 0.0
PHE D:23 D:685 0.0 0.0 E -94.1 124.2 NA NA NA
7mzy 1 Q9UM73 100.0 0.0 X-RAY
 2021-11-24 PHE A:14 A:685 0.0 0.0 E -93.8 135.3 0.0 0.0 0.0 HOH
 5.015
 O
 O
PHE B:14 B:685 0.0 0.0 E -95.7 133.9 0.0 0.0 0.0 HOH
 4.911
 O
 O
7lrz 1 Q9UM73 99.68 0.0 X-RAY
 2021-11-24 PHE A:10 A:685 0.0 0.0 E -105.6 129.6 0.0 0.0 0.0 HOH
 4.850
 O
 O
7nwz 2 Q9UM73 98.55 0.0 X-RAY
 2021-10-27 PHE B:38 F:685 0.0 0.0 E -112.6 130.9 0.0 0.0 0.0
PHE C:38 E:685 0.0 0.0 E -112.6 131.5 0.0 0.0 0.0
PHE D:38 B:685 0.0 0.0 E -110.8 129.6 NA NA NA
PHE E:38 A:685 0.0 0.0 E -114.5 128.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9um73-f1 1 Q9UM73 100.0 0.0 PHE A:685 A:685 0.0 0.0 E -93.5 136.7