Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 61719479 . C A CCDS33205.1:NM_003400.3:c.1704aaG>aaT_NP_003391.1:p.568K>N Homo sapiens exportin 1 (XPO1), mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3gb8 1 O14980 100.0 0.0 X-RAY
 2009-03-31 LYS A:568 A:568 79.0 0.395 H -63.6 -38.2 5.0 0.025 0.37 B:O95149:0.37
3gjx 3 Q6P5F9 98.04 0.0 X-RAY
 2009-05-26 LYS C:570 A:568 81.0 0.405 H -72.7 -32.7 13.0 0.065 0.34 A:O95149:0.34
 HOH
 3.976
 N
 O
LYS F:570 D:568 87.0 0.435 H -72.1 -31.9 NA NA NA
3nby 3 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LYS C:570 A:568 76.0 0.38 H -55.8 -41.4 16.0 0.08 0.3 A:O95149:0.3
LYS F:570 D:568 79.0 0.395 H -57.1 -42.9 NA NA NA
3nbz 1 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LYS A:570 A:568 77.0 0.385 H -62.4 -33.4 7.0 0.035 0.35 B:O95149:0.35
 HOH
 4.216
 NZ
 O
LYS D:570 D:568 81.0 0.405 H -67.8 -35.2 NA NA NA
3nc0 1 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LYS A:570 A:568 75.0 0.375 H -57.6 -40.2 9.0 0.045 0.33 B:O95149:0.33
 HOH
 6.584
 O
 O
LYS D:570 D:568 77.0 0.385 H -60.1 -40.6 77.0 0.385 0.0 HOH
 5.358
 N
 O
3nc1 2 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LYS B:570 A:568 100.0 0.5 H -71.2 -20.8 100.0 0.5 0.0
5dis 1 O14980 100.0 0.0 X-RAY
 2015-11-04 LYS A:564 A:568 85.0 0.425 H -63.1 -41.0 12.0 0.06 0.365 C:O95149:0.365
6tvo 2 O14980 99.71 0.0 X-RAY
 2020-07-08 LYS B:582 A:568 94.0 0.47 H -67.5 -46.2 94.0 0.47 0.0 LMB
 2.610
 NZ
 O2
7b51 2 O14980 99.71 0.0 X-RAY
 2021-03-10 LYS B:582 A:568 107.0 0.535 H -62.7 -40.6 107.0 0.535 0.0 BME
 3.810
 NZ
 O1
4bsm 1 O14980 100.0 0.0 X-RAY
 2013-07-31 LYS A:568 A:568 74.0 0.37 H -67.9 -33.1 74.0 0.37 0.0
4bsn 1 O14980 100.0 0.0 X-RAY
 2013-07-31 LYS A:568 A:568 71.0 0.355 H -71.4 -33.1 71.0 0.355 0.0
2l1l 2 O14980 100.0 1e-84 NMR
 2011-06-15 LYS B:65 B:568 108.0 0.54 H -72.5 -32.7 40.0 0.2 0.34 A:P61925:0.34

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o14980-f1 1 O14980 100.0 0.0 LYS A:568 A:568 92.0 0.46 H -67.6 -34.7