Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 61719608 . T A CCDS33205.1:NM_003400.3:c.1575ttA>ttT_NP_003391.1:p.525L>F Homo sapiens exportin 1 (XPO1), mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3gb8 1 O14980 100.0 0.0 X-RAY
 2009-03-31 LEU A:525 A:525 91.0 0.535 H -53.2 -48.6 8.0 0.047 0.488 B:O95149:0.488
3gjx 3 Q6P5F9 98.04 0.0 X-RAY
 2009-05-26 LEU C:527 A:525 88.0 0.518 H -52.3 -45.4 7.0 0.041 0.477 A:O95149:0.476
 HOH
 3.995
 C
 O
LEU F:527 D:525 90.0 0.529 H -57.0 -44.4 NA NA NA
3nby 3 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LEU C:527 A:525 78.0 0.459 H -61.8 -44.8 6.0 0.035 0.424 A:O95149:0.424
LEU F:527 D:525 79.0 0.465 H -60.2 -45.5 NA NA NA
3nbz 1 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LEU A:527 A:525 88.0 0.518 H -54.0 -44.4 15.0 0.088 0.43 B:O95149:0.429
 HOH
 3.560
 CB
 O
LEU D:527 D:525 88.0 0.518 H -53.1 -42.7 NA NA NA
3nc0 1 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LEU A:527 A:525 97.0 0.571 H -68.6 -20.8 8.0 0.047 0.524 B:O95149:0.524
 PEG
HOH
 3.627
6.398
 C
C
 O1
O
LEU D:527 D:525 95.0 0.559 H -67.6 -21.2 95.0 0.559 0.0 HOH
 3.230
 O
 O
3nc1 2 Q6P5F9 98.04 0.0 X-RAY
 2010-10-27 LEU B:527 A:525 88.0 0.518 H -66.9 -46.2 88.0 0.518 0.0
5dis 1 O14980 100.0 0.0 X-RAY
 2015-11-04 LEU A:521 A:525 95.0 0.559 H -62.9 -47.7 8.0 0.047 0.512 C:O95149:0.512
6tvo 2 O14980 99.71 0.0 X-RAY
 2020-07-08 LEU B:539 A:525 100.0 0.588 H -58.2 -44.9 100.0 0.588 0.0 LMB
 3.666
 CD2
 C28
7b51 2 O14980 99.71 0.0 X-RAY
 2021-03-10 LEU B:539 A:525 86.0 0.506 H -56.5 -50.5 86.0 0.506 0.0 BME
HOH
 5.113
6.494
 CD2
C
 S2
O
4bsm 1 O14980 100.0 0.0 X-RAY
 2013-07-31 LEU A:525 A:525 62.0 0.365 H -63.3 -41.2 62.0 0.365 0.0
4bsn 1 O14980 100.0 0.0 X-RAY
 2013-07-31 LEU A:525 A:525 67.0 0.394 H -70.3 -39.0 67.0 0.394 0.0
2l1l 2 O14980 100.0 1e-84 NMR
 2011-06-15 LEU B:22 B:525 95.0 0.559 H -52.1 -45.5 12.0 0.071 0.488 A:P61925:0.488

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o14980-f1 1 O14980 100.0 0.0 LEU A:525 A:525 92.0 0.541 H -64.5 -43.7