Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 70683612 . G A CCDS1905.1:NM_003236.3:c.224tCt>tTt_NP_003227.1:p.75S>F Homo sapiens transforming growth factor alpha (TGFA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mox 2 P01135 100.0 5e-32 X-RAY
 2003-09-10 SER C:36 C:36 121.0 1.0 T -39.7 131.6 103.0 0.896 0.104 A:P00533:0.157
 CD
HOH
 6.889
8.991
 O
O
 CD
O
SER D:36 D:36 118.0 1.0 T -50.1 141.3 102.0 0.887 0.113 B:P00533:0.139
 HOH
 6.857
 O
 O
2tgf 1 P01135 100.0 5e-32 NMR
 1993-04-15 SER A:36 A:36 130.0 1.0 T -60.4 99.0 130.0 1.0 0.0
3e50 2 P01135 100.0 5e-32 X-RAY
 2009-08-18 SER C:36 NA:NA DO NA DO DO DO NA NA NA
SER D:36 NA:NA DO NA DO DO DO NA NA NA
3tgf 1 P01135 100.0 5e-32 NMR
 1993-04-15 SER A:36 A:36 120.0 1.0 T -53.0 107.8 120.0 1.0 0.0
4tgf 1 P01135 100.0 5e-32 NMR
 1991-10-15 SER A:36 A:36 136.0 1.0 T -61.4 100.1 136.0 1.0 0.0
7sz5 2 P01135 100.0 5e-32 EM
 2021-12-22 SER B:36 C:36 117.0 1.0 S -73.9 149.1 104.0 0.904 0.096 A:P00533:0.113
SER D:36 D:36 121.0 1.0 T -71.4 143.0 99.0 0.861 0.139 C:P00533:0.191
7sz7 2 P01135 100.0 5e-32 EM
 2021-12-15 SER B:36 C:36 132.0 1.0 T -77.3 103.7 108.0 0.939 0.061 A:P00533:0.209
SER D:36 D:36 131.0 1.0 T -69.6 103.3 117.0 1.0 0.0 C:P00533:0.122
5kn5 3 P01135 100.0 5e-24 X-RAY
 2016-08-31 SER C:27 C:36 123.0 1.0 T -51.8 123.2 123.0 1.0 0.0 ZN
HOH
 6.930
3.118
 O
N
 ZN
O
SER F:27 F:36 108.0 0.939 T -34.7 133.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01135-f1 1 P01135 100.0 4e-114 SER A:75 A:75 122.0 1.0 T -54.0 128.2