Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 70692836 . G A CCDS1905.1:NM_003236.3:c.127Cat>Tat_NP_003227.1:p.43H>Y Homo sapiens transforming growth factor alpha (TGFA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1mox 2 P01135 100.0 5e-32 X-RAY
 2003-09-10 HIS C:4 C:4 102.0 0.523 S -79.3 -16.3 19.0 0.097 0.426 A:P00533:0.426
 HOH
 7.460
 CB
 O
HIS D:4 D:4 105.0 0.538 -77.5 -16.9 23.0 0.118 0.42 B:P00533:0.421
 HOH
 5.871
 CD2
 O
2tgf 1 P01135 100.0 5e-32 NMR
 1993-04-15 HIS A:4 A:4 112.0 0.574 T -115.1 52.4 112.0 0.574 0.0
3e50 2 P01135 100.0 5e-32 X-RAY
 2009-08-18 HIS C:4 C:4 164.0 0.841 -153.3 -137.7 150.0 0.769 0.072 A:P14735:0.072
 HOH
 4.695
 NE2
 O
HIS D:4 D:4 192.0 0.985 -56.0 15.4 NA NA NA
3tgf 1 P01135 100.0 5e-32 NMR
 1993-04-15 HIS A:4 A:4 140.0 0.718 T -49.2 -39.4 140.0 0.718 0.0
4tgf 1 P01135 100.0 5e-32 NMR
 1991-10-15 HIS A:4 A:4 142.0 0.728 S -156.0 4.7 142.0 0.728 0.0
7sz5 2 P01135 100.0 5e-32 EM
 2021-12-22 HIS B:4 C:4 83.0 0.426 S -71.5 -32.3 11.0 0.056 0.37 A:P00533:0.369
HIS D:4 D:4 73.0 0.374 S -52.3 -24.7 24.0 0.123 0.251 C:P00533:0.251
7sz7 2 P01135 100.0 5e-32 EM
 2021-12-15 HIS B:4 C:4 89.0 0.456 S 60.7 -2.5 8.0 0.041 0.415 A:P00533:0.415
HIS D:4 D:4 96.0 0.492 S -123.5 -2.3 15.0 0.077 0.415 C:P00533:0.415

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01135-f1 1 P01135 100.0 4e-114 HIS A:43 A:43 137.0 0.703 31.7 56.7