Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 74386298 . G A CCDS46340.1:NM_018221.3:c.493Cag>Tag_NP_060691.2:p.165Q>* Homo sapiens MOB kinase activator 1A (MOB1A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5twg 1 Q9H8S9 100.0 1e-165 X-RAY
 2017-04-12 GLN A:165 A:165 74.0 0.411 T -116.2 -58.8 74.0 0.411 0.0 ZN
 4.849
 CB
 ZN
5twh 1 Q9H8S9 100.0 1e-165 X-RAY
 2017-04-12 GLN A:165 A:165 72.0 0.4 T -81.6 -51.9 72.0 0.4 0.0 ZN
HOH
 4.502
4.030
 CB
O
 ZN
O
5brk 1 Q9H8S9 100.0 1e-165 X-RAY
 2015-07-08 GLN A:166 A:165 65.0 0.361 H -97.6 -23.4 65.0 0.361 0.0 ZN
HOH
 3.846
3.049
 HB2
HG3
 ZN
O
5twf 1 Q9H8S9 99.54 3e-165 X-RAY
 2017-04-12 GLN A:165 A:165 80.0 0.444 T -95.5 -43.8 80.0 0.444 0.0 ZN
 3.929
 OE1
 ZN
GLN B:165 B:165 96.0 0.533 T -63.1 -58.2 NA NA NA
5b5v 1 Q8BPB0 95.83 5e-159 X-RAY
 2016-07-06 GLN A:167 A:165 72.0 0.4 H -133.7 -12.0 72.0 0.4 0.0 ZN
HOH
 4.761
8.520
 CB
OE1
 ZN
O
GLN B:167 B:165 74.0 0.411 H -106.3 -16.0 NA NA NA
GLN C:167 C:165 73.0 0.406 H -133.5 -11.9 73.0 0.406 0.0 ZN
 4.692
 CB
 ZN
GLN D:167 D:165 71.0 0.394 H -106.4 -16.1 NA NA NA
GLN E:167 NA:NA DO NA DO DO DO NA NA NA
GLN F:167 NA:NA DO NA DO DO DO NA NA NA
5b6b 1 Q8BPB0 94.91 5e-157 X-RAY
 2016-07-06 GLN A:167 A:165 89.0 0.494 T -86.9 -52.3 89.0 0.494 0.0 ZN
 4.815
 CB
 ZN
GLN C:167 B:165 74.0 0.411 T -84.9 -51.7 74.0 0.411 0.0 ZN
 4.796
 CB
 ZN
GLN E:167 D:165 78.0 0.433 T -85.3 -52.0 NA NA NA
GLN G:167 F:165 90.0 0.5 T -86.2 -52.2 NA NA NA
GLN I:167 H:165 78.0 0.433 T -85.2 -52.4 NA NA NA
GLN K:167 K:165 86.0 0.478 T -85.6 -52.2 NA NA NA
GLN M:167 M:165 81.0 0.45 T -84.6 -51.9 NA NA NA
GLN O:167 O:165 77.0 0.428 T -85.0 -52.0 NA NA NA
5xqz 1 Q9H8S9 99.46 1e-141 X-RAY
 2018-08-29 GLN A:142 A:165 68.0 0.378 H -114.6 -22.7 68.0 0.378 0.0 ZN
HOH
 4.699
3.268
 CB
C
 ZN
O
GLN C:142 B:165 69.0 0.383 H -114.1 -15.9 NA NA NA
6mcp 2 Q9H8S9 99.46 1e-141 X-RAY
 2019-09-04 GLN B:136 B:165 68.0 0.378 H -114.2 -9.9 68.0 0.378 0.0 ZN
PEG
HOH
 4.524
7.126
3.780
 CB
N
O
 ZN
O1
O
GLN D:136 D:165 67.0 0.372 H -113.7 -8.7 NA NA NA
6mcq 2 Q9H8S9 99.46 1e-141 X-RAY
 2019-09-04 GLN B:136 B:165 71.0 0.394 H -113.3 -11.3 71.0 0.394 0.0 ZN
PEG
HOH
 4.764
6.969
3.799
 CB
N
O
 ZN
O2
O
GLN D:136 D:165 70.0 0.389 H -103.3 -14.2 NA NA NA
1pi1 1 Q9H8S9 100.0 2e-140 X-RAY
 2003-09-30 GLN A:134 A:144 73.0 0.406 H -109.9 -17.5 73.0 0.406 0.0 ZN
HOH
 4.507
2.694
 CB
NE2
 ZN
O
4j1v 1 Q9H8S9 100.0 2e-140 X-RAY
 2014-08-06 GLN A:133 A:165 67.0 0.372 H -106.2 -11.1 67.0 0.372 0.0 ZN
HOH
 4.638
2.703
 CB
O
 ZN
O
GLN B:133 C:165 69.0 0.383 H -106.0 -11.2 NA NA NA
5b5w 1 Q8BPB0 95.65 1e-134 X-RAY
 2016-07-06 GLN A:135 A:165 70.0 0.389 H -67.3 -37.4 70.0 0.389 0.0 ZN
 4.967
 CB
 ZN
5brm 1 Q9H8S9 99.44 5e-134 X-RAY
 2015-07-08 GLN A:126 A:165 78.0 0.433 H -106.5 -21.1 78.0 0.433 0.0 ZN
 3.778
 HB2
 ZN
GLN B:126 B:165 80.0 0.444 H -107.5 -21.9 80.0 0.444 0.0 ZN
 3.929
 HB2
 ZN
GLN C:126 C:165 76.0 0.422 H -106.6 -21.6 76.0 0.422 0.0 ZN
HOH
 4.164
2.912
 HB2
HE22
 ZN
O
GLN D:126 D:165 74.0 0.411 H -105.4 -21.8 74.0 0.411 0.0 ZN
 4.175
 HB2
 ZN
GLN E:126 E:165 84.0 0.467 H -107.1 -19.9 79.0 0.439 0.028 K:Q13188:0.028
 ZN
 3.897
 HB2
 ZN
GLN F:126 F:165 85.0 0.472 H -108.7 -19.5 85.0 0.472 0.0 ZN
 4.277
 HB2
 ZN
4jiz 1 Q9H8S9 100.0 9e-131 X-RAY
 2013-04-17 GLN A:126 A:144 68.0 0.378 H -113.4 -19.7 68.0 0.378 0.0 ZN
HOH
 4.113
3.236
 HB2
HG3
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9h8s9-f1 1 Q9H8S9 100.0 4e-166 GLN A:165 A:165 82.0 0.456 I -111.7 -23.6
af-q7l9l4-f1 1 Q7L9L4 95.83 1e-159 GLN A:165 A:165 82.0 0.456 H -117.2 -23.4