Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 74386300 . T A CCDS46340.1:NM_018221.3:c.491cAc>cTc_NP_060691.2:p.164H>L Homo sapiens MOB kinase activator 1A (MOB1A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5twg 1 Q9H8S9 100.0 1e-165 X-RAY
 2017-04-12 HIS A:164 A:164 81.0 0.415 H -73.6 -24.8 81.0 0.415 0.0 ZN
HOH
 8.167
4.697
 C
NE2
 ZN
O
5twh 1 Q9H8S9 100.0 1e-165 X-RAY
 2017-04-12 HIS A:164 A:164 78.0 0.4 H -71.9 -54.0 78.0 0.4 0.0 ZN
HOH
 7.941
7.546
 C
O
 ZN
O
5brk 1 Q9H8S9 100.0 1e-165 X-RAY
 2015-07-08 HIS A:165 A:164 42.0 0.215 H -73.1 -42.9 42.0 0.215 0.0 ZN
HOH
 7.723
3.077
 C
O
 ZN
O
5twf 1 Q9H8S9 99.54 3e-165 X-RAY
 2017-04-12 HIS A:164 A:164 89.0 0.456 H -74.8 -52.6 89.0 0.456 0.0 ZN
 7.888
 C
 ZN
HIS B:164 B:164 94.0 0.482 H -84.2 -64.5 NA NA NA
5b5v 1 Q8BPB0 95.83 5e-159 X-RAY
 2016-07-06 HIS A:166 A:164 85.0 0.436 H -72.2 -16.2 85.0 0.436 0.0 ZN
HOH
 8.020
8.504
 C
CD2
 ZN
O
HIS B:166 B:164 84.0 0.431 H -78.2 -42.0 NA NA NA
HIS C:166 C:164 82.0 0.421 H -72.1 -16.4 82.0 0.421 0.0 ZN
HOH
 7.951
5.025
 C
CE1
 ZN
O
HIS D:166 D:164 80.0 0.41 H -78.3 -42.1 NA NA NA
HIS E:166 NA:NA DO NA DO DO DO NA NA NA
HIS F:166 NA:NA DO NA DO DO DO NA NA NA
5b6b 1 Q8BPB0 94.91 5e-157 X-RAY
 2016-07-06 HIS A:166 A:164 77.0 0.395 H -86.9 -55.4 77.0 0.395 0.0 ZN
 8.186
 C
 ZN
HIS C:166 B:164 15.0 0.077 H -86.6 -53.6 15.0 0.077 0.0 ZN
 8.182
 C
 ZN
HIS E:166 D:164 45.0 0.231 H -86.1 -54.3 NA NA NA
HIS G:166 F:164 73.0 0.374 H -85.4 -54.9 NA NA NA
HIS I:166 H:164 17.0 0.087 H -86.1 -54.2 NA NA NA
HIS K:166 K:164 79.0 0.405 H -85.4 -54.4 NA NA NA
HIS M:166 M:164 77.0 0.395 H -86.3 -53.7 NA NA NA
HIS O:166 O:164 77.0 0.395 H -86.4 -54.0 NA NA NA
5xqz 1 Q9H8S9 99.46 1e-141 X-RAY
 2018-08-29 HIS A:141 A:164 83.0 0.426 H -75.2 -34.3 83.0 0.426 0.0 ZN
HOH
 8.046
2.501
 C
ND1
 ZN
O
HIS C:141 B:164 82.0 0.421 H -76.7 -37.8 NA NA NA
6mcp 2 Q9H8S9 99.46 1e-141 X-RAY
 2019-09-04 HIS B:135 B:164 78.0 0.4 H -80.6 -34.7 78.0 0.4 0.0 ZN
PEG
HOH
 7.850
3.756
8.079
 C
NE2
C
 ZN
C1
O
HIS D:135 D:164 82.0 0.421 H -81.2 -36.3 NA NA NA
6mcq 2 Q9H8S9 99.46 1e-141 X-RAY
 2019-09-04 HIS B:135 B:164 82.0 0.421 H -72.6 -38.3 82.0 0.421 0.0 ZN
PEG
HOH
 8.040
3.659
5.900
 C
NE2
CE1
 ZN
C1
O
HIS D:135 D:164 82.0 0.421 H -81.4 -44.3 NA NA NA
1pi1 1 Q9H8S9 100.0 2e-140 X-RAY
 2003-09-30 HIS A:133 A:143 76.0 0.39 H -73.3 -38.1 76.0 0.39 0.0 ZN
HOH
 7.800
2.892
 C
ND1
 ZN
O
4j1v 1 Q9H8S9 100.0 2e-140 X-RAY
 2014-08-06 HIS A:132 A:164 73.0 0.374 H -79.0 -40.4 39.0 0.2 0.174 D:Q99IB8:0.174
 ZN
HOH
 7.944
2.680
 C
ND1
 ZN
O
HIS B:132 C:164 72.0 0.369 H -78.8 -40.5 NA NA NA
5b5w 1 Q8BPB0 95.65 1e-134 X-RAY
 2016-07-06 HIS A:134 A:164 59.0 0.303 H -91.0 -65.4 59.0 0.303 0.0 ZN
 8.255
 C
 ZN
5brm 1 Q9H8S9 99.44 5e-134 X-RAY
 2015-07-08 HIS A:125 A:164 83.0 0.426 H -74.8 -40.2 42.0 0.215 0.211 G:Q13188:0.21
 ZN
 7.651
 C
 ZN
HIS B:125 B:164 80.0 0.41 H -75.0 -40.9 36.0 0.185 0.225 H:Q13188:0.226
 ZN
 7.807
 C
 ZN
HIS C:125 C:164 80.0 0.41 H -75.5 -41.6 39.0 0.2 0.21 I:Q13188:0.21
 ZN
HOH
 8.018
8.017
 C
O
 ZN
O
HIS D:125 D:164 80.0 0.41 H -76.0 -40.4 47.0 0.241 0.169 J:Q13188:0.169
 ZN
 8.052
 C
 ZN
HIS E:125 E:164 80.0 0.41 H -76.0 -40.8 30.0 0.154 0.256 K:Q13188:0.256
 ZN
 7.778
 C
 ZN
HIS F:125 F:164 79.0 0.405 H -75.8 -42.4 42.0 0.215 0.19 L:Q13188:0.19
 ZN
 8.096
 C
 ZN
4jiz 1 Q9H8S9 100.0 9e-131 X-RAY
 2013-04-17 HIS A:125 A:143 80.0 0.41 H -71.9 -37.5 80.0 0.41 0.0 ZN
HOH
 8.011
2.933
 C
O
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9h8s9-f1 1 Q9H8S9 100.0 4e-166 HIS A:164 A:164 82.0 0.421 I -87.7 -34.6
af-q7l9l4-f1 1 Q7L9L4 95.83 1e-159 HIS A:164 A:164 81.0 0.415 H -83.8 -30.7