Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 74392410 . A C CCDS46340.1:NM_018221.3:c.344aTt>aGt_NP_060691.2:p.115I>S Homo sapiens MOB kinase activator 1A (MOB1A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5twg 1 Q9H8S9 100.0 1e-165 X-RAY
 2017-04-12 ILE A:115 A:115 2.0 0.011 H -63.1 -36.2 2.0 0.011 0.0 ZN
 5.941
 CD1
 ZN
5twh 1 Q9H8S9 100.0 1e-165 X-RAY
 2017-04-12 ILE A:115 A:115 3.0 0.017 H -63.7 -32.9 3.0 0.017 0.0 ZN
HOH
 6.083
6.515
 CD1
CD1
 ZN
O
5brk 1 Q9H8S9 100.0 1e-165 X-RAY
 2015-07-08 ILE A:116 A:115 1.0 0.006 H -70.5 -29.7 1.0 0.006 0.0 ZN
HOH
 5.157
3.729
 HD12
HB
 ZN
O
5twf 1 Q9H8S9 99.54 3e-165 X-RAY
 2017-04-12 ILE A:115 A:115 4.0 0.023 H -60.1 -41.4 4.0 0.023 0.0 ZN
 7.477
 CG1
 ZN
ILE B:115 B:115 4.0 0.023 H -57.1 -47.2 NA NA NA
5b5v 1 Q8BPB0 95.83 5e-159 X-RAY
 2016-07-06 ILE A:117 A:115 1.0 0.006 H -70.4 -30.3 1.0 0.006 0.0 ZN
HOH
 5.723
4.768
 CD1
O
 ZN
O
ILE B:117 B:115 1.0 0.006 H -72.2 -34.0 NA NA NA
ILE C:117 C:115 2.0 0.011 H -70.0 -30.4 2.0 0.011 0.0 ZN
HOH
 5.792
8.489
 CD1
N
 ZN
O
ILE D:117 D:115 1.0 0.006 H -72.1 -33.8 NA NA NA
ILE E:117 NA:NA DO NA DO DO DO NA NA NA
ILE F:117 NA:NA DO NA DO DO DO NA NA NA
5b6b 1 Q8BPB0 94.91 5e-157 X-RAY
 2016-07-06 ILE A:117 A:115 2.0 0.011 H -65.7 -33.8 0.0 0.0 0.011 B:Q8BYR2:0.011
 ZN
 5.756
 CD1
 ZN
ILE C:117 B:115 1.0 0.006 H -65.4 -35.3 1.0 0.006 0.0 ZN
 5.321
 CD1
 ZN
ILE E:117 D:115 1.0 0.006 H -65.9 -35.0 NA NA NA
ILE G:117 F:115 3.0 0.017 H -64.3 -33.9 NA NA NA
ILE I:117 H:115 1.0 0.006 H -66.6 -36.0 NA NA NA
ILE K:117 K:115 2.0 0.011 H -64.4 -33.8 NA NA NA
ILE M:117 M:115 2.0 0.011 H -65.2 -35.1 NA NA NA
ILE O:117 O:115 1.0 0.006 H -65.6 -35.5 NA NA NA
5xqz 1 Q9H8S9 99.46 1e-141 X-RAY
 2018-08-29 ILE A:92 A:115 3.0 0.017 H -67.0 -41.2 3.0 0.017 0.0 ZN
HOH
 5.750
3.989
 CD1
O
 ZN
O
ILE C:92 B:115 4.0 0.023 H -68.5 -38.5 NA NA NA
6mcp 2 Q9H8S9 99.46 1e-141 X-RAY
 2019-09-04 ILE B:86 B:115 0.0 0.0 H -76.5 -38.5 0.0 0.0 0.0 ZN
HOH
 5.611
5.459
 CD1
CG2
 ZN
O
ILE D:86 D:115 0.0 0.0 H -76.4 -37.0 NA NA NA
6mcq 2 Q9H8S9 99.46 1e-141 X-RAY
 2019-09-04 ILE B:86 B:115 0.0 0.0 H -73.5 -33.1 0.0 0.0 0.0 ZN
HOH
 5.617
6.405
 CD1
C
 ZN
O
ILE D:86 D:115 0.0 0.0 H -69.5 -28.4 NA NA NA
1pi1 1 Q9H8S9 100.0 2e-140 X-RAY
 2003-09-30 ILE A:84 A:94 2.0 0.011 H -62.7 -31.8 2.0 0.011 0.0 ZN
HOH
 5.725
4.648
 CD1
CB
 ZN
O
4j1v 1 Q9H8S9 100.0 2e-140 X-RAY
 2014-08-06 ILE A:83 A:115 0.0 0.0 H -66.8 -40.2 0.0 0.0 0.0 ZN
HOH
 5.541
4.507
 CD1
C
 ZN
O
ILE B:83 C:115 0.0 0.0 H -66.8 -39.7 NA NA NA
5b5w 1 Q8BPB0 95.65 1e-134 X-RAY
 2016-07-06 ILE A:85 A:115 0.0 0.0 H -79.6 -46.1 0.0 0.0 0.0 ZN
 5.404
 CD1
 ZN
5brm 1 Q9H8S9 99.44 5e-134 X-RAY
 2015-07-08 ILE A:76 A:115 4.0 0.023 H -63.8 -32.1 0.0 0.0 0.023 M:Q13188:0.023
 ZN
 5.390
 HD12
 ZN
ILE B:76 B:115 4.0 0.023 H -64.4 -32.9 0.0 0.0 0.023 N:Q13188:0.023
 ZN
 5.244
 HD12
 ZN
ILE C:76 C:115 6.0 0.034 H -59.7 -32.8 6.0 0.034 0.0 ZN
 5.444
 HD11
 ZN
ILE D:76 D:115 4.0 0.023 H -64.2 -35.1 1.0 0.006 0.017 O:Q13188:0.017
 ZN
 5.402
 HD12
 ZN
ILE E:76 E:115 3.0 0.017 H -64.2 -32.1 3.0 0.017 0.0 ZN
 5.255
 HD12
 ZN
ILE F:76 F:115 4.0 0.023 H -62.8 -34.3 4.0 0.023 0.0 ZN
 5.870
 HD12
 ZN
4jiz 1 Q9H8S9 100.0 9e-131 X-RAY
 2013-04-17 ILE A:76 A:94 1.0 0.006 H -72.3 -36.3 1.0 0.006 0.0 ZN
HOH
 5.335
3.500
 HD12
HB
 ZN
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9h8s9-f1 1 Q9H8S9 100.0 4e-166 ILE A:115 A:115 1.0 0.006 H -68.5 -39.2
af-q7l9l4-f1 1 Q7L9L4 95.83 1e-159 ILE A:115 A:115 1.0 0.006 H -68.6 -39.0