Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 98263572 . G A CCDS2032.1:NM_001862.2:c.146aGg>aAg_NP_001853.2:p.49R>K Homo sapiens cytochrome c oxidase subunit 5B (COX5B), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2y69 6 P00428 82.95 1e-81 X-RAY
2011-02-23 ARG F:49 F:18 67.0 0.298 H -62.5 -45.5 67.0 0.298 0.0 PGV
HOH
9.141
2.881
N
NH2
O06
O
ARG S:49 S:18 61.0 0.271 H -63.5 -45.5 NA NA NA
5z62 6 P10606 100.0 3e-71 EM
2019-02-27 ARG F:18 F:49 91.0 0.404 H -71.8 -39.5 91.0 0.404 0.0
7o37 18 P19536 85.86 2e-64 EM
2021-10-13 ARG BA:19 f:19 75.0 0.333 H -65.5 -40.2 75.0 0.333 0.0
7o3c 18 P19536 85.86 2e-64 EM
2021-10-13 ARG BA:19 f:19 82.0 0.364 H -66.4 -49.0 82.0 0.364 0.0
7o3e 16 P19536 85.86 2e-64 EM
2021-10-13 ARG V:19 f:19 71.0 0.316 H -63.9 -39.3 71.0 0.316 0.0
5j4z 67 W5PW27 86.73 2e-64 EM
2016-09-21 ARG DC:18 BP:18 34.0 NA H -60.1 -47.6 34.0 NA NA
5j7y 67 W5PW27 86.73 2e-64 EM
2016-09-21 ARG DC:18 BP:18 33.0 NA H -60.1 -47.6 33.0 NA NA
1occ 6 P00428 85.71 5e-64 X-RAY
1996-12-07 ARG F:18 F:18 65.0 0.289 H -59.9 -44.1 65.0 0.289 0.0
ARG S:18 S:18 64.0 0.284 H -59.9 -44.1 64.0 0.284 0.0
1oco 6 P00428 85.71 5e-64 X-RAY
1999-07-22 ARG F:18 F:18 63.0 0.28 H -65.0 -39.6 63.0 0.28 0.0
ARG S:18 S:18 62.0 0.276 H -64.8 -39.7 62.0 0.276 0.0
1ocr 6 P00428 85.71 5e-64 X-RAY
1999-07-29 ARG F:18 F:18 75.0 0.333 H -65.1 -42.8 75.0 0.333 0.0
ARG S:18 S:18 73.0 0.324 H -64.1 -42.8 73.0 0.324 0.0
1ocz 6 P00428 85.71 5e-64 X-RAY
1999-07-22 ARG F:18 F:18 61.0 0.271 H -66.4 -44.0 61.0 0.271 0.0
ARG S:18 S:18 60.0 0.267 H -67.8 -44.2 60.0 0.267 0.0
1v54 6 P00428 85.71 5e-64 X-RAY
2003-12-23 ARG F:18 F:18 65.0 0.289 H -66.2 -42.9 65.0 0.289 0.0 PGV
HOH
9.067
3.165
N
NH2
C06
O
ARG S:18 S:18 63.0 0.28 H -64.4 -44.3 63.0 0.28 0.0 PGV
HOH
9.097
3.326
N
NE
O06
O
1v55 6 P00428 85.71 5e-64 X-RAY
2003-12-23 ARG F:18 F:18 65.0 0.289 H -63.5 -41.4 65.0 0.289 0.0 PGV
HOH
9.042
3.058
N
NH2
C06
O
ARG S:18 S:18 61.0 0.271 H -62.7 -42.1 61.0 0.271 0.0 PGV
HOH
9.098
3.218
N
NE
C06
O
2dyr 6 P00428 85.71 5e-64 X-RAY
2007-04-03 ARG F:18 F:18 66.0 0.293 H -65.5 -43.0 66.0 0.293 0.0 PGV
HOH
9.095
3.182
N
NH2
O06
O
ARG S:18 S:18 63.0 0.28 H -64.7 -43.4 63.0 0.28 0.0 PGV
HOH
9.142
3.266
N
NE
O06
O
2dys 6 P00428 85.71 5e-64 X-RAY
2007-04-03 ARG F:18 F:18 64.0 0.284 H -67.0 -44.5 64.0 0.284 0.0 PGV
HOH
9.099
2.990
N
NH2
O06
O
ARG S:18 S:18 64.0 0.284 H -66.1 -46.5 64.0 0.284 0.0 PGV
HOH
9.234
2.962
N
NH2
O06
O
2eij 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ARG F:18 F:18 64.0 0.284 H -62.6 -42.7 64.0 0.284 0.0 PGV
HOH
9.082
3.017
N
NH2
C06
O
ARG S:18 S:18 62.0 0.276 H -61.1 -44.2 62.0 0.276 0.0 PGV
HOH
9.124
3.090
N
CG
O06
O
2eik 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ARG F:18 F:18 64.0 0.284 H -64.2 -43.2 64.0 0.284 0.0 PGV
HOH
9.122
3.260
N
NH2
C06
O
ARG S:18 S:18 63.0 0.28 H -63.7 -42.8 63.0 0.28 0.0 PGV
HOH
9.146
3.386
N
NE
C06
O
2eil 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ARG F:18 F:18 64.0 0.284 H -67.6 -43.4 64.0 0.284 0.0 PGV
HOH
9.120
3.174
N
NH2
O06
O
ARG S:18 S:18 65.0 0.289 H -66.4 -45.2 65.0 0.289 0.0 PGV
HOH
9.180
3.391
N
CB
O06
O
2eim 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ARG F:18 F:18 62.0 0.276 H -62.9 -47.9 62.0 0.276 0.0 PGV
HOH
9.169
3.029
N
CB
C06
O
ARG S:18 S:18 66.0 0.293 H -60.7 -51.9 66.0 0.293 0.0 PGV
HOH
9.186
4.035
N
NE
C06
O
2ein 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ARG F:18 F:18 75.0 0.333 H -66.4 -48.0 75.0 0.333 0.0 PGV
ZN
HOH
9.190
6.794
3.500
N
N
NE
O06
ZN
O
ARG S:18 S:18 71.0 0.316 H -67.4 -48.5 71.0 0.316 0.0 ZN
PGV
HOH
6.733
9.358
3.013
N
N
NH2
ZN
O06
O
2occ 6 P00428 85.71 5e-64 X-RAY
1999-01-13 ARG F:18 F:18 74.0 0.329 H -67.1 -44.1 74.0 0.329 0.0
ARG S:18 S:18 74.0 0.329 H -65.4 -44.6 NA NA NA
2ybb 25 P00428 85.71 5e-64 EM
2011-10-19 ARG Y:18 Q:18 64.0 0.284 H -59.8 -44.2 64.0 0.284 0.0
2zxw 6 P00428 85.71 5e-64 X-RAY
2009-02-24 ARG F:18 F:18 64.0 0.284 H -61.4 -50.4 64.0 0.284 0.0 PGV
HOH
9.070
3.634
N
NE
O06
O
ARG S:18 S:18 61.0 0.271 H -64.0 -49.7 NA NA NA
3abk 6 P00428 85.71 5e-64 X-RAY
2010-03-09 ARG F:18 F:18 62.0 0.276 H -66.2 -43.1 62.0 0.276 0.0 PGV
HOH
9.039
3.212
N
NE
O06
O
ARG S:18 S:18 63.0 0.28 H -65.2 -43.7 NA NA NA
3abl 6 P00428 85.71 5e-64 X-RAY
2010-01-19 ARG F:18 F:18 62.0 0.276 H -57.1 -47.1 62.0 0.276 0.0 PGV
HOH
8.996
2.914
N
NH2
O06
O
ARG S:18 S:18 64.0 0.284 H -56.0 -45.4 NA NA NA
3abm 6 P00428 85.71 5e-64 X-RAY
2010-01-19 ARG F:18 F:18 65.0 0.289 H -65.6 -39.0 65.0 0.289 0.0 PGV
HOH
9.065
3.420
N
NE
C06
O
ARG S:18 S:18 59.0 0.262 H -54.8 -49.8 NA NA NA
3ag1 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ARG F:18 F:18 68.0 0.302 H -63.5 -45.8 68.0 0.302 0.0 PGV
HOH
9.041
2.851
N
NH2
O06
O
ARG S:18 S:18 67.0 0.298 H -60.0 -42.0 NA NA NA
3ag2 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ARG F:18 F:18 63.0 0.28 H -66.9 -38.2 63.0 0.28 0.0 PGV
EDO
EDO
HOH
9.030
8.802
6.113
3.161
N
N
N
NH2
C06
C1
O1
O
ARG S:18 S:18 62.0 0.276 H -67.6 -39.1 NA NA NA
3ag3 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ARG F:18 F:18 65.0 0.289 H -58.8 -43.7 65.0 0.289 0.0 PGV
HOH
9.033
3.454
N
NE
C06
O
ARG S:18 S:18 63.0 0.28 H -70.9 -36.0 NA NA NA
3ag4 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ARG F:18 F:18 63.0 0.28 H -66.3 -42.8 63.0 0.28 0.0 PGV
HOH
9.127
2.851
N
NH2
O06
O
ARG S:18 S:18 64.0 0.284 H -60.0 -45.0 NA NA NA
3asn 6 P00428 85.71 5e-64 X-RAY
2011-08-03 ARG F:18 F:18 65.0 0.289 H -56.7 -41.8 65.0 0.289 0.0 PGV
HOH
9.131
3.112
N
NH2
C06
O
ARG S:18 S:18 67.0 0.298 H -59.9 -45.9 NA NA NA
3aso 6 P00428 85.71 5e-64 X-RAY
2011-08-03 ARG F:18 F:18 66.0 0.293 H -60.8 -39.9 66.0 0.293 0.0 PGV
HOH
9.139
2.943
N
NH2
C06
O
ARG S:18 S:18 67.0 0.298 H -62.3 -47.3 NA NA NA
3wg7 6 P00428 85.71 5e-64 X-RAY
2014-04-30 ARG F:18 F:18 68.0 0.302 H -65.3 -39.8 68.0 0.302 0.0 PGV
HOH
9.206
2.858
N
NH2
C06
O
ARG S:18 S:18 66.0 0.293 H -61.3 -42.4 NA NA NA
3x2q 6 P00428 85.71 5e-64 X-RAY
2015-06-10 ARG F:18 F:18 65.0 0.289 H -64.0 -42.7 65.0 0.289 0.0 PGV
HOH
9.145
2.927
N
NH2
C06
O
ARG S:18 S:18 67.0 0.298 H -64.5 -42.1 NA NA NA
5b1a 6 P00428 85.71 5e-64 X-RAY
2016-09-14 ARG F:18 F:18 61.0 0.271 H -64.5 -38.4 61.0 0.271 0.0 PGV
HOH
9.125
2.913
N
NH2
C06
O
ARG S:18 S:18 62.0 0.276 H -66.5 -38.4 NA NA NA
5b1b 6 P00428 85.71 5e-64 X-RAY
2016-09-14 ARG F:18 F:18 61.0 0.271 H -65.6 -37.7 61.0 0.271 0.0 PGV
HOH
9.109
2.919
N
NH2
C06
O
ARG S:18 S:18 62.0 0.276 H -68.5 -37.2 NA NA NA
5b3s 6 P00428 85.71 5e-64 X-RAY
2017-03-22 ARG F:18 F:18 64.0 0.284 H -61.9 -44.3 64.0 0.284 0.0 PGV
EDO
HOH
9.049
6.010
2.897
N
N
NH2
O06
O1
O
ARG S:18 S:18 65.0 0.289 H -62.4 -43.3 NA NA NA
5gpn 39 P00428 85.71 5e-64 EM
2017-04-05 ARG ZA:18 3:18 30.0 NA H -59.7 -44.1 30.0 NA NA
5gup 65 ? 85.71 5e-64 EM
2017-03-29 ARG ZB:18 Ap:18 64.0 0.284 H -59.9 -44.1 64.0 0.284 0.0
5iy5 6 P00428 85.71 5e-64 X-RAY
2017-01-11 ARG F:18 F:18 63.0 0.28 H -67.6 -41.8 63.0 0.28 0.0 PGV
EDO
HOH
9.148
6.034
3.611
N
N
CD
C06
O2
O
ARG S:18 S:18 64.0 0.284 H -60.2 -45.4 NA NA NA
5luf 17 P00428 85.71 5e-64 EM
2016-11-30 ARG BA:18 3:18 64.0 0.284 H -59.8 -44.2 64.0 0.284 0.0
5w97 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ARG F:18 F:18 78.0 0.347 H -63.5 -50.5 78.0 0.347 0.0 PGV
HOH
9.312
2.679
N
NH2
O06
O
ARG S:18 f:18 70.0 0.311 H -62.1 -37.4 70.0 0.311 0.0 PGV
HOH
8.709
3.831
N
CB
O06
O
5wau 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ARG F:18 F:18 65.0 0.289 H -61.5 -47.1 65.0 0.289 0.0 PGV
HOH
9.003
3.386
N
CB
O06
O
ARG S:18 f:18 66.0 0.293 H -67.1 -43.5 66.0 0.293 0.0 PGV
HOH
9.088
3.579
N
CB
O06
O
5x19 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ARG F:18 F:18 78.0 0.347 H -64.2 -50.0 78.0 0.347 0.0 PGV
HOH
9.234
3.891
N
NH1
O06
O
ARG S:18 S:18 68.0 0.302 H -60.6 -48.0 NA NA NA
5x1b 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ARG F:18 F:18 73.0 0.324 H -62.2 -49.4 73.0 0.324 0.0 PGV
HOH
9.136
3.189
N
CB
O06
O
ARG S:18 S:18 70.0 0.311 H -52.4 -48.5 NA NA NA
5x1f 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ARG F:18 F:18 69.0 0.307 H -63.0 -50.6 69.0 0.307 0.0 PGV
HOH
9.070
3.692
N
NE
O06
O
ARG S:18 S:18 67.0 0.298 H -63.3 -47.4 NA NA NA
5xth 50 P00428 85.71 5e-64 EM
2017-09-13 ARG YA:18 2:18 67.0 0.298 H -60.0 -44.0 67.0 0.298 0.0
5xti 50 P00428 85.71 5e-64 EM
2017-09-13 ARG YA:18 2:18 65.0 0.289 H -59.9 -44.1 65.0 0.289 0.0
ARG AE:18 B2:18 67.0 0.298 H -59.9 -44.0 67.0 0.298 0.0
5z84 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ARG F:18 F:18 67.0 0.298 H -69.5 -41.4 67.0 0.298 0.0 PGV
EDO
EDO
HOH
9.136
9.383
6.135
2.952
N
N
N
NE
O06
O2
O1
O
ARG S:18 S:18 63.0 0.28 H -65.2 -41.2 NA NA NA
5z85 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ARG F:18 F:18 66.0 0.293 H -67.8 -43.3 66.0 0.293 0.0 PGV
EDO
EDO
HOH
9.136
9.326
6.084
3.170
N
N
N
NE
O06
O2
O1
O
ARG S:18 S:18 65.0 0.289 H -63.3 -45.1 NA NA NA
5z86 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ARG F:18 F:18 65.0 0.289 H -66.3 -42.4 65.0 0.289 0.0 PGV
EDO
EDO
HOH
9.134
9.279
6.169
3.254
N
N
N
NE
O06
O2
O1
O
ARG S:18 S:18 63.0 0.28 H -62.7 -44.1 NA NA NA
5zco 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ARG F:18 F:18 67.0 0.298 H -68.4 -41.4 67.0 0.298 0.0 PGV
EDO
HOH
9.155
6.138
3.002
N
N
NE
C06
O1
O
ARG S:18 S:18 66.0 0.293 H -65.6 -43.7 NA NA NA
5zcp 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ARG F:18 F:18 67.0 0.298 H -63.6 -42.0 67.0 0.298 0.0 PGV
EDO
HOH
9.088
6.117
3.184
N
N
NE
O06
O1
O
ARG S:18 S:18 63.0 0.28 H -63.6 -39.4 NA NA NA
5zcq 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ARG F:18 F:18 65.0 0.289 H -63.9 -40.2 65.0 0.289 0.0 PGV
EDO
EDO
HOH
9.088
9.435
6.071
3.105
N
N
N
NE
O06
O2
O1
O
ARG S:18 S:18 63.0 0.28 H -65.5 -39.1 NA NA NA
6j8m 6 P00428 85.71 5e-64 X-RAY
2019-06-26 ARG F:18 F:18 64.0 0.284 H -64.1 -40.1 64.0 0.284 0.0 PGV
HOH
9.102
2.797
N
NH2
O06
O
ARG S:18 S:18 65.0 0.289 H -62.9 -44.3 NA NA NA
6juw 6 P00428 85.71 5e-64 X-RAY
2020-03-25 ARG F:18 F:18 65.0 0.289 H -66.6 -43.8 65.0 0.289 0.0 PGV
EDO
EDO
EDO
EDO
HOH
9.051
8.559
8.602
5.987
9.050
2.840
N
N
N
N
O
NE
C06
C2
O2
O1
O2
O
ARG S:18 S:18 65.0 0.289 H -60.7 -43.6 65.0 0.289 0.0 PGV
EDO
EDO
EDO
EDO
HOH
9.029
9.297
9.576
6.068
6.247
3.293
N
N
O
N
CB
CG
O06
O1
O2
O1
O1
O
6jy3 6 P00428 85.71 5e-64 X-RAY
2019-09-18 ARG F:18 F:18 61.0 0.271 H -66.4 -43.6 61.0 0.271 0.0 PGV
HOH
9.059
2.695
N
NE
O06
O
6jy4 6 P00428 85.71 5e-64 X-RAY
2019-09-18 ARG F:18 F:18 60.0 0.267 H -66.3 -44.5 60.0 0.267 0.0 PGV
HOH
9.060
2.695
N
NE
C06
O
6nkn 6 P00428 85.71 5e-64 X-RAY
2019-03-20 ARG F:18 F:18 73.0 0.324 H -59.0 -53.1 73.0 0.324 0.0 PGV
HOH
9.226
3.554
N
CB
O06
O
ARG S:18 S:18 69.0 0.307 H -62.7 -41.9 69.0 0.307 0.0 PGV
HOH
9.061
5.250
N
N
O06
O
6nmf 6 P00428 85.71 5e-64 X-RAY
2019-03-13 ARG F:18 F:18 64.0 0.284 H -64.9 -51.7 64.0 0.284 0.0 PGV
HOH
9.393
3.491
N
CB
O06
O
ARG S:18 S:18 69.0 0.307 H -59.9 -44.8 69.0 0.307 0.0 PGV
HOH
9.143
6.613
N
O
O06
O
6nmp 6 P00428 85.71 5e-64 X-RAY
2019-03-13 ARG F:18 F:18 69.0 0.307 H -59.3 -58.6 69.0 0.307 0.0 PGV
HOH
9.261
4.916
N
C
O06
O
ARG S:18 S:18 63.0 0.28 H -64.1 -52.2 63.0 0.28 0.0 PGV
HOH
8.809
6.318
N
N
O06
O
7coh 6 P00428 85.71 5e-64 X-RAY
2021-04-07 ARG F:18 F:18 64.0 0.284 H -67.6 -41.8 64.0 0.284 0.0 PGV
EDO
HOH
9.155
6.088
2.850
N
N
NE
O06
O1
O
ARG S:18 S:18 63.0 0.28 H -66.4 -41.2 NA NA NA
7ev7 6 P00428 85.71 5e-64 X-RAY
2021-07-14 ARG F:18 F:18 65.0 0.289 H -67.6 -39.1 65.0 0.289 0.0 PGV
EDO
EDO
EDO
HOH
9.065
9.198
6.079
7.162
2.906
N
N
N
CD
NH2
C06
C1
O1
C1
O
ARG S:18 S:18 65.0 0.289 H -66.0 -40.0 NA NA NA
5xdq 6 P00428 85.11 9e-61 X-RAY
2017-07-12 ARG F:18 F:18 64.0 0.284 H -64.4 -43.0 64.0 0.284 0.0 PGV
EDO
HOH
9.056
6.103
2.914
N
N
NH2
O06
O1
O
ARG S:18 S:18 64.0 0.284 H -62.2 -44.5 NA NA NA
5xdx 6 P00428 85.11 9e-61 X-RAY
2018-02-07 ARG F:18 F:18 65.0 0.289 H -62.9 -46.5 65.0 0.289 0.0 PGV
EDO
HOH
9.086
6.081
2.928
N
N
NE
O06
O1
O
ARG S:18 S:18 64.0 0.284 H -61.6 -46.4 NA NA NA
7cp5 6 P00428 85.11 9e-61 X-RAY
2021-07-21 ARG F:18 F:18 66.0 0.293 H -69.3 -38.6 66.0 0.293 0.0 PGV
EDO
EDO
EDO
EDO
HOH
9.076
8.940
8.412
6.115
6.657
2.817
N
N
N
N
CD
NH2
C06
C1
C2
O2
O1
O
ARG S:18 S:18 64.0 0.284 H -67.5 -40.0 64.0 0.284 0.0 PGV
EDO
EDO
EDO
HOH
9.081
9.287
6.125
6.789
3.194
N
N
N
CD
CG
O06
O2
O1
O1
O
7d5w 6 P00428 85.11 9e-61 X-RAY
2021-07-21 ARG F:18 F:18 65.0 0.289 H -66.1 -41.2 65.0 0.289 0.0 PGV
EDO
EDO
EDO
EDO
HOH
9.098
8.999
8.476
6.055
6.740
2.923
N
N
N
N
CD
NH2
C06
C1
C2
O2
O1
O
ARG S:18 S:18 63.0 0.28 H -67.1 -39.5 63.0 0.28 0.0 PGV
EDO
EDO
EDO
HOH
9.134
9.338
6.197
6.997
3.213
N
N
N
CD
CG
O06
O2
O1
O1
O
7d5x 6 P00428 85.11 9e-61 X-RAY
2021-07-21 ARG F:18 F:18 65.0 0.289 H -69.5 -39.8 65.0 0.289 0.0 PGV
EDO
EDO
EDO
HOH
9.055
9.107
6.094
6.764
2.837
N
N
N
CD
NH2
C06
C1
O2
O1
O
ARG S:18 S:18 64.0 0.284 H -67.2 -40.9 64.0 0.284 0.0 PGV
EDO
EDO
EDO
HOH
9.102
9.243
6.130
6.799
3.301
N
N
N
CD
CG
O06
O2
O1
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p10606-f1 1 P10606 100.0 8e-94 ARG A:49 A:49 81.0 0.36 H -61.7 -41.1