Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 98263883 . A C CCDS2032.1:NM_001862.2:c.254aAc>aCc_NP_001853.2:p.85N>T Homo sapiens cytochrome c oxidase subunit 5B (COX5B), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2y69 6 P00428 82.95 1e-81 X-RAY
2011-02-23 ASN F:85 F:54 77.0 0.481 S -101.2 14.6 77.0 0.481 0.0 HOH
3.252
CB
O
ASN S:85 S:54 92.0 0.575 S -86.0 -21.0 NA NA NA
5z62 6 P10606 100.0 3e-71 EM
2019-02-27 ASN F:54 F:85 95.0 0.594 S -86.8 11.5 95.0 0.594 0.0
7o37 18 P19536 85.86 2e-64 EM
2021-10-13 ASN BA:55 f:55 81.0 0.506 S -81.6 -12.5 76.0 0.475 0.031 Z:P19783:0.031
7o3c 18 P19536 85.86 2e-64 EM
2021-10-13 ASN BA:55 f:55 87.0 0.544 S -101.5 29.5 87.0 0.544 0.0
7o3e 16 P19536 85.86 2e-64 EM
2021-10-13 ASN V:55 f:55 84.0 0.525 S -83.2 -8.9 72.0 0.45 0.075 T:P19783:0.075
5j4z 67 W5PW27 86.73 2e-64 EM
2016-09-21 ASN DC:54 BP:54 78.0 NA S -66.2 -19.1 78.0 NA NA
5j7y 67 W5PW27 86.73 2e-64 EM
2016-09-21 ASN DC:54 BP:54 78.0 NA S -66.2 -19.1 78.0 NA NA
1occ 6 P00428 85.71 5e-64 X-RAY
1996-12-07 ASN F:54 F:54 86.0 0.537 S -119.1 20.9 86.0 0.537 0.0
ASN S:54 S:54 85.0 0.531 S -119.0 20.9 85.0 0.531 0.0
1oco 6 P00428 85.71 5e-64 X-RAY
1999-07-22 ASN F:54 F:54 92.0 0.575 S -117.4 11.7 92.0 0.575 0.0
ASN S:54 S:54 91.0 0.569 S -117.3 12.0 91.0 0.569 0.0
1ocr 6 P00428 85.71 5e-64 X-RAY
1999-07-29 ASN F:54 F:54 74.0 0.463 S -105.5 16.0 74.0 0.463 0.0
ASN S:54 S:54 73.0 0.456 S -106.2 16.0 73.0 0.456 0.0
1ocz 6 P00428 85.71 5e-64 X-RAY
1999-07-22 ASN F:54 F:54 91.0 0.569 S -66.8 -3.6 91.0 0.569 0.0
ASN S:54 S:54 89.0 0.556 S -69.2 -1.5 89.0 0.556 0.0
1v54 6 P00428 85.71 5e-64 X-RAY
2003-12-23 ASN F:54 F:54 78.0 0.487 S -98.9 13.3 78.0 0.487 0.0 HOH
4.143
O
O
ASN S:54 S:54 80.0 0.5 S -97.4 5.7 80.0 0.5 0.0 HOH
6.358
N
O
1v55 6 P00428 85.71 5e-64 X-RAY
2003-12-23 ASN F:54 F:54 78.0 0.487 S -98.2 12.5 78.0 0.487 0.0 HOH
3.054
O
O
ASN S:54 S:54 83.0 0.519 S -97.8 6.3 83.0 0.519 0.0 HOH
2.860
ND2
O
2dyr 6 P00428 85.71 5e-64 X-RAY
2007-04-03 ASN F:54 F:54 79.0 0.494 S -94.9 5.3 79.0 0.494 0.0 HOH
4.030
O
O
ASN S:54 S:54 98.0 0.613 S -77.0 -25.6 98.0 0.613 0.0 HOH
6.327
N
O
2dys 6 P00428 85.71 5e-64 X-RAY
2007-04-03 ASN F:54 F:54 79.0 0.494 S -98.6 17.3 79.0 0.494 0.0 HOH
2.725
O
O
ASN S:54 S:54 86.0 0.537 S -95.0 7.0 86.0 0.537 0.0 HOH
4.103
N
O
2eij 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ASN F:54 F:54 75.0 0.469 S -100.8 16.3 75.0 0.469 0.0 HOH
2.870
O
O
ASN S:54 S:54 83.0 0.519 S -97.8 6.9 83.0 0.519 0.0 HOH
3.018
ND2
O
2eik 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ASN F:54 F:54 80.0 0.5 S -95.5 13.7 80.0 0.5 0.0 HOH
2.550
OD1
O
ASN S:54 S:54 84.0 0.525 S -94.7 7.1 84.0 0.525 0.0 HOH
3.857
OD1
O
2eil 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ASN F:54 F:54 81.0 0.506 S -97.8 15.8 81.0 0.506 0.0 HOH
2.592
OD1
O
ASN S:54 S:54 82.0 0.512 S -96.0 7.0 82.0 0.512 0.0 HOH
6.969
O
O
2eim 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ASN F:54 F:54 80.0 0.5 S -94.3 20.8 80.0 0.5 0.0 HOH
2.961
O
O
ASN S:54 S:54 82.0 0.512 S -93.8 15.4 82.0 0.512 0.0 HOH
6.873
O
O
2ein 6 P00428 85.71 5e-64 X-RAY
2007-05-29 ASN F:54 F:54 79.0 0.494 S -89.1 15.5 79.0 0.494 0.0 HOH
4.054
O
O
ASN S:54 S:54 87.0 0.544 S -81.8 5.1 87.0 0.544 0.0 HOH
3.033
ND2
O
2occ 6 P00428 85.71 5e-64 X-RAY
1999-01-13 ASN F:54 F:54 76.0 0.475 S -104.0 5.1 76.0 0.475 0.0
ASN S:54 S:54 75.0 0.469 S -107.4 6.5 NA NA NA
2ybb 25 P00428 85.71 5e-64 EM
2011-10-19 ASN Y:54 Q:54 87.0 0.544 S -119.2 21.0 87.0 0.544 0.0
2zxw 6 P00428 85.71 5e-64 X-RAY
2009-02-24 ASN F:54 F:54 79.0 0.494 S -94.0 8.5 79.0 0.494 0.0 HOH
2.650
N
O
ASN S:54 S:54 94.0 0.588 S -66.7 -34.7 NA NA NA
3abk 6 P00428 85.71 5e-64 X-RAY
2010-03-09 ASN F:54 F:54 73.0 0.456 S -100.3 8.5 73.0 0.456 0.0 HOH
4.139
O
O
ASN S:54 S:54 83.0 0.519 S -107.9 10.9 NA NA NA
3abl 6 P00428 85.71 5e-64 X-RAY
2010-01-19 ASN F:54 F:54 74.0 0.463 S -95.8 14.7 74.0 0.463 0.0 HOH
2.629
ND2
O
ASN S:54 S:54 89.0 0.556 S -74.6 -22.2 NA NA NA
3abm 6 P00428 85.71 5e-64 X-RAY
2010-01-19 ASN F:54 F:54 76.0 0.475 S -100.1 15.0 76.0 0.475 0.0 HOH
3.166
O
O
ASN S:54 S:54 84.0 0.525 S -75.8 -24.5 NA NA NA
3ag1 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ASN F:54 F:54 82.0 0.512 S -98.8 13.1 82.0 0.512 0.0 HOH
3.007
N
O
ASN S:54 S:54 81.0 0.506 S -102.3 2.6 NA NA NA
3ag2 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ASN F:54 F:54 98.0 0.613 S -96.4 7.7 98.0 0.613 0.0 HOH
3.028
O
O
ASN S:54 S:54 93.0 0.581 S -103.6 9.7 NA NA NA
3ag3 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ASN F:54 F:54 88.0 0.55 S -93.9 2.4 88.0 0.55 0.0 HOH
4.630
N
O
ASN S:54 S:54 89.0 0.556 S -87.4 -10.9 NA NA NA
3ag4 6 P00428 85.71 5e-64 X-RAY
2010-04-28 ASN F:54 F:54 79.0 0.494 S -93.2 8.0 79.0 0.494 0.0 HOH
2.603
OD1
O
ASN S:54 S:54 99.0 0.619 S -71.4 -28.3 NA NA NA
3asn 6 P00428 85.71 5e-64 X-RAY
2011-08-03 ASN F:54 F:54 77.0 0.481 S -98.8 6.6 77.0 0.481 0.0 HOH
2.525
CB
O
ASN S:54 S:54 90.0 0.562 S -46.8 -32.2 NA NA NA
3aso 6 P00428 85.71 5e-64 X-RAY
2011-08-03 ASN F:54 F:54 77.0 0.481 S -96.2 8.7 77.0 0.481 0.0 HOH
2.761
CB
O
ASN S:54 S:54 89.0 0.556 S -67.2 -30.9 NA NA NA
3wg7 6 P00428 85.71 5e-64 X-RAY
2014-04-30 ASN F:54 F:54 95.0 0.594 S -95.7 10.0 95.0 0.594 0.0 HOH
3.437
ND2
O
ASN S:54 S:54 80.0 0.5 S -101.3 10.7 NA NA NA
3x2q 6 P00428 85.71 5e-64 X-RAY
2015-06-10 ASN F:54 F:54 97.0 0.606 S -98.3 11.2 97.0 0.606 0.0 HOH
2.673
CB
O
ASN S:54 S:54 84.0 0.525 S -101.6 6.7 NA NA NA
5b1a 6 P00428 85.71 5e-64 X-RAY
2016-09-14 ASN F:54 F:54 97.0 0.606 S -83.1 1.9 97.0 0.606 0.0 HOH
2.449
OD1
O
ASN S:54 S:54 82.0 0.512 S -104.4 6.8 NA NA NA
5b1b 6 P00428 85.71 5e-64 X-RAY
2016-09-14 ASN F:54 F:54 72.0 0.45 S -105.7 23.2 72.0 0.45 0.0 HOH
2.475
ND2
O
ASN S:54 S:54 81.0 0.506 S -104.9 5.6 NA NA NA
5b3s 6 P00428 85.71 5e-64 X-RAY
2017-03-22 ASN F:54 F:54 97.0 0.606 S -100.1 13.3 97.0 0.606 0.0 HOH
2.559
ND2
O
ASN S:54 S:54 81.0 0.506 S -104.2 5.9 NA NA NA
5gpn 39 P00428 85.71 5e-64 EM
2017-04-05 ASN ZA:54 3:54 65.0 NA S -119.2 20.9 65.0 NA NA
5gup 65 ? 85.71 5e-64 EM
2017-03-29 ASN ZB:54 Ap:54 86.0 0.537 S -119.2 20.9 86.0 0.537 0.0
5iy5 6 P00428 85.71 5e-64 X-RAY
2017-01-11 ASN F:54 F:54 77.0 0.481 S -99.6 13.3 66.0 0.412 0.069 D:P00423:0.069
HOH
2.955
O
O
ASN S:54 S:54 84.0 0.525 S -113.1 15.6 NA NA NA
5luf 17 P00428 85.71 5e-64 EM
2016-11-30 ASN BA:54 3:54 86.0 0.537 S -119.2 21.0 86.0 0.537 0.0
5w97 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ASN F:54 F:54 102.0 0.637 S -96.5 2.5 102.0 0.637 0.0 HOH
4.303
CB
O
ASN S:54 f:54 88.0 0.55 S -99.7 3.7 83.0 0.519 0.031 Q:P00423:0.031
HOH
6.545
N
O
5wau 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ASN F:54 F:54 97.0 0.606 S -85.2 1.0 97.0 0.606 0.0 HOH
2.761
OD1
O
ASN S:54 f:54 79.0 0.494 S -95.7 2.2 66.0 0.412 0.082 Q:P00423:0.081
HOH
2.899
O
O
5x19 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ASN F:54 F:54 105.0 0.656 S -95.4 0.7 105.0 0.656 0.0 HOH
3.049
N
O
ASN S:54 S:54 85.0 0.531 S -99.3 2.6 NA NA NA
5x1b 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ASN F:54 F:54 98.0 0.613 S -101.5 8.1 98.0 0.613 0.0 HOH
4.942
N
O
ASN S:54 S:54 76.0 0.475 S -110.2 14.1 NA NA NA
5x1f 6 P00428 85.71 5e-64 X-RAY
2017-08-09 ASN F:54 F:54 104.0 0.65 S -99.6 11.6 104.0 0.65 0.0 HOH
2.975
O
O
ASN S:54 S:54 81.0 0.506 S -96.2 0.1 NA NA NA
5xth 50 P00428 85.71 5e-64 EM
2017-09-13 ASN YA:54 2:54 86.0 0.537 S -119.4 21.1 86.0 0.537 0.0
5xti 50 P00428 85.71 5e-64 EM
2017-09-13 ASN YA:54 2:54 87.0 0.544 S -119.4 21.0 87.0 0.544 0.0
ASN AE:54 B2:54 86.0 0.537 S -119.4 21.1 86.0 0.537 0.0
5z84 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ASN F:54 F:54 102.0 0.637 S -94.1 16.7 102.0 0.637 0.0 HOH
2.825
O
O
ASN S:54 S:54 82.0 0.512 S -108.9 11.9 NA NA NA
5z85 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ASN F:54 F:54 91.0 0.569 S -87.9 8.7 91.0 0.569 0.0 HOH
4.604
ND2
O
ASN S:54 S:54 82.0 0.512 S -110.2 11.8 NA NA NA
5z86 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ASN F:54 F:54 94.0 0.588 S -102.5 14.8 94.0 0.588 0.0 HOH
2.897
O
O
ASN S:54 S:54 85.0 0.531 S -101.5 7.9 NA NA NA
5zco 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ASN F:54 F:54 88.0 0.55 S -91.1 11.2 88.0 0.55 0.0 HOH
2.855
O
O
ASN S:54 S:54 83.0 0.519 S -106.7 11.1 NA NA NA
5zcp 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ASN F:54 F:54 88.0 0.55 S -90.0 10.4 88.0 0.55 0.0 HOH
2.730
OD1
O
ASN S:54 S:54 83.0 0.519 S -108.2 9.5 NA NA NA
5zcq 6 P00428 85.71 5e-64 X-RAY
2018-08-15 ASN F:54 F:54 86.0 0.537 S -78.6 -7.2 86.0 0.537 0.0 HOH
3.532
ND2
O
ASN S:54 S:54 77.0 0.481 S -110.4 6.3 NA NA NA
6j8m 6 P00428 85.71 5e-64 X-RAY
2019-06-26 ASN F:54 F:54 75.0 0.469 S -102.1 18.2 75.0 0.469 0.0 HOH
2.672
OD1
O
ASN S:54 S:54 82.0 0.512 S -102.7 6.2 NA NA NA
6juw 6 P00428 85.71 5e-64 X-RAY
2020-03-25 ASN F:54 F:54 93.0 0.581 S -98.5 16.5 93.0 0.581 0.0 EDO
HOH
9.640
2.705
N
OD1
O1
O
ASN S:54 S:54 85.0 0.531 S -106.8 11.4 83.0 0.519 0.012 Q:P00423:0.013
EDO
EDO
HOH
9.531
9.967
2.711
N
N
OD1
O1
C2
O
6jy3 6 P00428 85.71 5e-64 X-RAY
2019-09-18 ASN F:54 F:54 94.0 0.588 S -100.4 10.1 94.0 0.588 0.0 HOH
6.364
N
O
6jy4 6 P00428 85.71 5e-64 X-RAY
2019-09-18 ASN F:54 F:54 88.0 0.55 S -101.4 14.3 88.0 0.55 0.0 HOH
7.165
O
O
6nkn 6 P00428 85.71 5e-64 X-RAY
2019-03-20 ASN F:54 F:54 103.0 0.644 S -85.1 -14.0 103.0 0.644 0.0 HOH
6.227
N
O
ASN S:54 S:54 87.0 0.544 S -99.8 5.7 87.0 0.544 0.0 HOH
6.602
N
O
6nmf 6 P00428 85.71 5e-64 X-RAY
2019-03-13 ASN F:54 F:54 88.0 0.55 S -80.6 -2.2 88.0 0.55 0.0 HOH
2.776
O
O
ASN S:54 S:54 75.0 0.469 S -114.7 12.0 75.0 0.469 0.0 HOH
2.625
ND2
O
6nmp 6 P00428 85.71 5e-64 X-RAY
2019-03-13 ASN F:54 F:54 90.0 0.562 S -105.1 11.4 90.0 0.562 0.0 HOH
9.341
N
O
ASN S:54 S:54 80.0 0.5 S -98.7 -3.9 80.0 0.5 0.0 HOH
3.704
OD1
O
7coh 6 P00428 85.71 5e-64 X-RAY
2021-04-07 ASN F:54 F:54 85.0 0.531 S -100.5 17.1 85.0 0.531 0.0 HOH
2.973
O
O
ASN S:54 S:54 80.0 0.5 S -103.3 6.1 NA NA NA
7ev7 6 P00428 85.71 5e-64 X-RAY
2021-07-14 ASN F:54 F:54 88.0 0.55 S -101.6 17.9 88.0 0.55 0.0 HOH
3.127
O
O
ASN S:54 S:54 84.0 0.525 S -107.1 7.4 NA NA NA
5xdq 6 P00428 85.11 9e-61 X-RAY
2017-07-12 ASN F:54 F:54 93.0 0.581 S -97.8 8.6 93.0 0.581 0.0 HOH
2.648
ND2
O
ASN S:54 S:54 82.0 0.512 S -97.2 6.1 NA NA NA
5xdx 6 P00428 85.11 9e-61 X-RAY
2018-02-07 ASN F:54 F:54 97.0 0.606 S -94.3 4.3 97.0 0.606 0.0 HOH
3.211
CA
O
ASN S:54 S:54 85.0 0.531 S -95.7 7.0 NA NA NA
7cp5 6 P00428 85.11 9e-61 X-RAY
2021-07-21 ASN F:54 F:54 93.0 0.581 S -101.9 16.2 93.0 0.581 0.0 EDO
HOH
9.775
6.324
N
N
O2
O
ASN S:54 S:54 68.0 0.425 S -105.3 6.0 68.0 0.425 0.0 EDO
HOH
9.959
2.704
N
OD1
C1
O
7d5w 6 P00428 85.11 9e-61 X-RAY
2021-07-21 ASN F:54 F:54 94.0 0.588 S -103.3 15.2 94.0 0.588 0.0 EDO
HOH
9.689
2.994
N
O
O2
O
ASN S:54 S:54 69.0 0.431 S -102.6 8.5 69.0 0.431 0.0 HOH
2.814
OD1
O
7d5x 6 P00428 85.11 9e-61 X-RAY
2021-07-21 ASN F:54 F:54 76.0 0.475 S -99.1 14.6 76.0 0.475 0.0 EDO
EDO
HOH
9.677
8.749
2.734
N
N
OD1
O2
C2
O
ASN S:54 S:54 79.0 0.494 S -106.9 8.2 79.0 0.494 0.0 EDO
HOH
9.953
2.606
N
OD1
C1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p10606-f1 1 P10606 100.0 8e-94 ASN A:85 A:85 104.0 0.65 S -77.0 0.9