Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 98264548 . G A CCDS2032.1:NM_001862.2:c.367Gtg>Atg_NP_001853.2:p.123V>M Homo sapiens cytochrome c oxidase subunit 5B (COX5B), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2y69 6 P00428 82.95 1e-81 X-RAY
2011-02-23 VAL F:123 F:92 62.0 0.4 E -123.1 82.9 62.0 0.4 0.0 HOH
4.701
O
O
VAL S:123 S:92 57.0 0.368 E -123.9 94.5 NA NA NA
5z62 6 P10606 100.0 3e-71 EM
2019-02-27 VAL F:92 F:123 44.0 0.284 E -125.2 120.4 44.0 0.284 0.0
7o37 18 P19536 85.86 2e-64 EM
2021-10-13 VAL BA:93 f:93 38.0 0.245 E -120.0 84.9 38.0 0.245 0.0
7o3c 18 P19536 85.86 2e-64 EM
2021-10-13 VAL BA:93 f:93 35.0 0.226 E -121.0 103.8 35.0 0.226 0.0
7o3e 16 P19536 85.86 2e-64 EM
2021-10-13 VAL V:93 f:93 46.0 0.297 E -120.9 85.5 46.0 0.297 0.0
5j4z 67 W5PW27 86.73 2e-64 EM
2016-09-21 VAL DC:92 BP:92 33.0 NA -79.0 108.8 33.0 NA NA
5j7y 67 W5PW27 86.73 2e-64 EM
2016-09-21 VAL DC:92 BP:92 33.0 NA -79.0 108.9 33.0 NA NA
1occ 6 P00428 85.71 5e-64 X-RAY
1996-12-07 VAL F:92 F:92 47.0 0.303 E -150.9 143.3 47.0 0.303 0.0
VAL S:92 S:92 46.0 0.297 E -150.9 143.3 46.0 0.297 0.0
1oco 6 P00428 85.71 5e-64 X-RAY
1999-07-22 VAL F:92 F:92 45.0 0.29 E -156.5 143.1 45.0 0.29 0.0
VAL S:92 S:92 45.0 0.29 E -158.0 146.4 45.0 0.29 0.0
1ocr 6 P00428 85.71 5e-64 X-RAY
1999-07-29 VAL F:92 F:92 48.0 0.31 E -152.7 150.3 48.0 0.31 0.0
VAL S:92 S:92 49.0 0.316 E -151.2 151.3 49.0 0.316 0.0
1ocz 6 P00428 85.71 5e-64 X-RAY
1999-07-22 VAL F:92 F:92 44.0 0.284 E -146.2 150.3 44.0 0.284 0.0
VAL S:92 S:92 45.0 0.29 E -147.7 150.1 45.0 0.29 0.0
1v54 6 P00428 85.71 5e-64 X-RAY
2003-12-23 VAL F:92 F:92 63.0 0.406 E -126.3 86.8 63.0 0.406 0.0 HOH
4.787
N
O
VAL S:92 S:92 66.0 0.426 E -124.2 89.4 66.0 0.426 0.0 HOH
5.876
N
O
1v55 6 P00428 85.71 5e-64 X-RAY
2003-12-23 VAL F:92 F:92 65.0 0.419 E -127.3 87.9 65.0 0.419 0.0 HOH
2.741
O
O
VAL S:92 S:92 64.0 0.413 E -126.2 89.7 64.0 0.413 0.0 HOH
4.790
O
O
2dyr 6 P00428 85.71 5e-64 X-RAY
2007-04-03 VAL F:92 F:92 63.0 0.406 E -124.2 86.5 63.0 0.406 0.0 HOH
4.767
N
O
VAL S:92 S:92 66.0 0.426 E -123.2 89.4 66.0 0.426 0.0 HOH
5.852
N
O
2dys 6 P00428 85.71 5e-64 X-RAY
2007-04-03 VAL F:92 F:92 64.0 0.413 E -127.9 75.6 64.0 0.413 0.0 HOH
4.167
O
O
VAL S:92 S:92 62.0 0.4 E -127.7 75.0 62.0 0.4 0.0 HOH
5.354
O
O
2eij 6 P00428 85.71 5e-64 X-RAY
2007-05-29 VAL F:92 F:92 66.0 0.426 E -125.5 87.2 66.0 0.426 0.0 HOH
2.694
O
O
VAL S:92 S:92 64.0 0.413 E -124.8 89.5 64.0 0.413 0.0 HOH
4.663
O
O
2eik 6 P00428 85.71 5e-64 X-RAY
2007-05-29 VAL F:92 F:92 62.0 0.4 E -124.0 84.4 62.0 0.4 0.0 HOH
4.512
O
O
VAL S:92 S:92 66.0 0.426 E -123.7 85.7 66.0 0.426 0.0 HOH
4.770
O
O
2eil 6 P00428 85.71 5e-64 X-RAY
2007-05-29 VAL F:92 F:92 62.0 0.4 E -125.4 80.9 62.0 0.4 0.0 HOH
2.919
O
O
VAL S:92 S:92 65.0 0.419 E -124.5 82.8 65.0 0.419 0.0 HOH
4.513
O
O
2eim 6 P00428 85.71 5e-64 X-RAY
2007-05-29 VAL F:92 F:92 63.0 0.406 E -118.2 76.9 63.0 0.406 0.0 HOH
5.626
N
O
VAL S:92 S:92 64.0 0.413 E -117.1 77.1 64.0 0.413 0.0 HOH
2.785
O
O
2ein 6 P00428 85.71 5e-64 X-RAY
2007-05-29 VAL F:92 F:92 63.0 0.406 E -133.2 69.7 63.0 0.406 0.0 HOH
3.259
CG2
O
VAL S:92 S:92 64.0 0.413 E -134.1 72.2 64.0 0.413 0.0 HOH
6.026
N
O
2occ 6 P00428 85.71 5e-64 X-RAY
1999-01-13 VAL F:92 F:92 47.0 0.303 E -142.2 153.1 47.0 0.303 0.0
VAL S:92 S:92 49.0 0.316 E -140.5 155.1 NA NA NA
2ybb 25 P00428 85.71 5e-64 EM
2011-10-19 VAL Y:92 Q:92 45.0 0.29 E -150.9 143.3 45.0 0.29 0.0
2zxw 6 P00428 85.71 5e-64 X-RAY
2009-02-24 VAL F:92 F:92 63.0 0.406 E -122.2 75.9 63.0 0.406 0.0 HOH
3.026
O
O
VAL S:92 S:92 61.0 0.394 E -116.8 73.7 NA NA NA
3abk 6 P00428 85.71 5e-64 X-RAY
2010-03-09 VAL F:92 F:92 64.0 0.413 E -121.3 92.2 64.0 0.413 0.0 HOH
2.813
O
O
VAL S:92 S:92 60.0 0.387 E -123.8 81.2 NA NA NA
3abl 6 P00428 85.71 5e-64 X-RAY
2010-01-19 VAL F:92 F:92 63.0 0.406 E -133.5 84.4 63.0 0.406 0.0 HOH
3.658
CG1
O
VAL S:92 S:92 57.0 0.368 E -127.4 93.4 NA NA NA
3abm 6 P00428 85.71 5e-64 X-RAY
2010-01-19 VAL F:92 F:92 63.0 0.406 E -124.1 81.6 63.0 0.406 0.0 HOH
4.749
N
O
VAL S:92 S:92 55.0 0.355 E -126.8 88.7 NA NA NA
3ag1 6 P00428 85.71 5e-64 X-RAY
2010-04-28 VAL F:92 F:92 56.0 0.361 E -111.1 95.5 56.0 0.361 0.0 HOH
3.443
CG1
O
VAL S:92 S:92 59.0 0.381 E -117.8 96.7 NA NA NA
3ag2 6 P00428 85.71 5e-64 X-RAY
2010-04-28 VAL F:92 F:92 63.0 0.406 E -123.8 84.3 63.0 0.406 0.0 EDO
HOH
7.418
4.813
CG2
N
O2
O
VAL S:92 S:92 68.0 0.439 E -124.2 94.7 NA NA NA
3ag3 6 P00428 85.71 5e-64 X-RAY
2010-04-28 VAL F:92 F:92 61.0 0.394 E -119.7 87.1 61.0 0.394 0.0 HOH
5.850
N
O
VAL S:92 S:92 61.0 0.394 E -121.2 86.2 NA NA NA
3ag4 6 P00428 85.71 5e-64 X-RAY
2010-04-28 VAL F:92 F:92 62.0 0.4 E -124.0 87.2 62.0 0.4 0.0 HOH
2.982
O
O
VAL S:92 S:92 57.0 0.368 E -120.8 86.6 NA NA NA
3asn 6 P00428 85.71 5e-64 X-RAY
2011-08-03 VAL F:92 F:92 63.0 0.406 E -120.1 85.7 63.0 0.406 0.0 HOH
3.334
CG1
O
VAL S:92 S:92 57.0 0.368 E -118.7 99.3 NA NA NA
3aso 6 P00428 85.71 5e-64 X-RAY
2011-08-03 VAL F:92 F:92 63.0 0.406 E -119.7 85.1 63.0 0.406 0.0 HOH
3.192
CG1
O
VAL S:92 S:92 58.0 0.374 E -118.9 99.9 NA NA NA
3wg7 6 P00428 85.71 5e-64 X-RAY
2014-04-30 VAL F:92 F:92 62.0 0.4 E -123.3 91.8 62.0 0.4 0.0 HOH
2.700
O
O
VAL S:92 S:92 53.0 0.342 E -123.0 87.7 NA NA NA
3x2q 6 P00428 85.71 5e-64 X-RAY
2015-06-10 VAL F:92 F:92 59.0 0.381 E -116.2 89.1 59.0 0.381 0.0 HOH
4.697
O
O
VAL S:92 S:92 54.0 0.348 E -116.5 110.7 NA NA NA
5b1a 6 P00428 85.71 5e-64 X-RAY
2016-09-14 VAL F:92 F:92 61.0 0.394 E -123.5 87.6 61.0 0.394 0.0 HOH
2.696
O
O
VAL S:92 S:92 54.0 0.348 E -125.2 80.7 NA NA NA
5b1b 6 P00428 85.71 5e-64 X-RAY
2016-09-14 VAL F:92 F:92 60.0 0.387 E -131.3 88.7 60.0 0.387 0.0 HOH
2.666
O
O
VAL S:92 S:92 53.0 0.342 E -127.3 95.2 NA NA NA
5b3s 6 P00428 85.71 5e-64 X-RAY
2017-03-22 VAL F:92 F:92 59.0 0.381 E -121.8 88.1 59.0 0.381 0.0 EDO
HOH
7.264
2.669
CG2
O
O2
O
VAL S:92 S:92 55.0 0.355 E -122.1 92.3 NA NA NA
5gpn 39 P00428 85.71 5e-64 EM
2017-04-05 VAL ZA:92 3:92 43.0 NA E -150.9 143.4 43.0 NA NA
5gup 65 ? 85.71 5e-64 EM
2017-03-29 VAL ZB:92 Ap:92 47.0 0.303 E -151.0 143.3 47.0 0.303 0.0
5iy5 6 P00428 85.71 5e-64 X-RAY
2017-01-11 VAL F:92 F:92 45.0 0.29 E -134.6 161.1 45.0 0.29 0.0 HOH
3.812
CB
O
VAL S:92 S:92 42.0 0.271 E -111.2 89.5 NA NA NA
5luf 17 P00428 85.71 5e-64 EM
2016-11-30 VAL BA:92 3:92 46.0 0.297 E -150.9 143.2 46.0 0.297 0.0
5w97 6 P00428 85.71 5e-64 X-RAY
2017-08-09 VAL F:92 F:92 32.0 0.206 E -124.9 97.8 32.0 0.206 0.0 HOH
3.715
CA
O
VAL S:92 f:92 41.0 0.265 E -135.7 170.1 41.0 0.265 0.0 HOH
5.248
N
O
5wau 6 P00428 85.71 5e-64 X-RAY
2017-08-09 VAL F:92 F:92 34.0 0.219 E -116.3 88.7 34.0 0.219 0.0 HOH
2.967
C
O
VAL S:92 f:92 43.0 0.277 E -128.5 159.0 43.0 0.277 0.0 HOH
4.937
N
O
5x19 6 P00428 85.71 5e-64 X-RAY
2017-08-09 VAL F:92 F:92 43.0 0.277 E -127.9 152.3 43.0 0.277 0.0 EDO
HOH
7.521
3.218
CG2
C
O2
O
VAL S:92 S:92 40.0 0.258 E -125.1 143.9 NA NA NA
5x1b 6 P00428 85.71 5e-64 X-RAY
2017-08-09 VAL F:92 F:92 43.0 0.277 E -132.1 141.4 43.0 0.277 0.0 EDO
HOH
7.318
3.252
CG1
CG2
O2
O
VAL S:92 S:92 42.0 0.271 E -128.0 142.3 NA NA NA
5x1f 6 P00428 85.71 5e-64 X-RAY
2017-08-09 VAL F:92 F:92 42.0 0.271 E -106.8 107.9 42.0 0.271 0.0 EDO
HOH
7.628
4.729
CG2
N
O2
O
VAL S:92 S:92 42.0 0.271 E -117.3 152.8 NA NA NA
5xth 50 P00428 85.71 5e-64 EM
2017-09-13 VAL YA:92 2:92 48.0 0.31 E -151.0 143.4 48.0 0.31 0.0
5xti 50 P00428 85.71 5e-64 EM
2017-09-13 VAL YA:92 2:92 47.0 0.303 E -150.9 143.4 47.0 0.303 0.0
VAL AE:92 B2:92 48.0 0.31 E -151.0 143.4 48.0 0.31 0.0
5z84 6 P00428 85.71 5e-64 X-RAY
2018-08-15 VAL F:92 F:92 58.0 0.374 E -125.9 89.5 58.0 0.374 0.0 HOH
2.674
O
O
VAL S:92 S:92 56.0 0.361 E -123.7 93.3 NA NA NA
5z85 6 P00428 85.71 5e-64 X-RAY
2018-08-15 VAL F:92 F:92 61.0 0.394 E -128.1 87.3 61.0 0.394 0.0 HOH
4.752
N
O
VAL S:92 S:92 55.0 0.355 E -123.8 92.3 NA NA NA
5z86 6 P00428 85.71 5e-64 X-RAY
2018-08-15 VAL F:92 F:92 55.0 0.355 E -125.2 89.2 55.0 0.355 0.0 HOH
2.688
O
O
VAL S:92 S:92 56.0 0.361 E -120.8 101.9 NA NA NA
5zco 6 P00428 85.71 5e-64 X-RAY
2018-08-15 VAL F:92 F:92 60.0 0.387 E -124.7 87.1 60.0 0.387 0.0 EDO
EDO
HOH
6.689
7.440
2.572
O
CG1
O
C1
O1
O
VAL S:92 S:92 57.0 0.368 E -125.7 91.2 NA NA NA
5zcp 6 P00428 85.71 5e-64 X-RAY
2018-08-15 VAL F:92 F:92 59.0 0.381 E -124.3 85.9 59.0 0.381 0.0 EDO
EDO
HOH
6.662
7.419
2.619
O
CG1
O
C1
O1
O
VAL S:92 S:92 55.0 0.355 E -126.6 89.3 NA NA NA
5zcq 6 P00428 85.71 5e-64 X-RAY
2018-08-15 VAL F:92 F:92 59.0 0.381 E -125.8 84.0 59.0 0.381 0.0 EDO
EDO
EDO
HOH
6.937
6.678
7.256
2.649
O
CG2
CG2
O
C2
O1
O2
O
VAL S:92 S:92 54.0 0.348 E -120.3 89.6 NA NA NA
6j8m 6 P00428 85.71 5e-64 X-RAY
2019-06-26 VAL F:92 F:92 61.0 0.394 E -130.8 88.7 61.0 0.394 0.0 HOH
2.717
O
O
VAL S:92 S:92 54.0 0.348 E -122.1 92.6 NA NA NA
6juw 6 P00428 85.71 5e-64 X-RAY
2020-03-25 VAL F:92 F:92 52.0 0.335 E -127.5 81.0 52.0 0.335 0.0 EDO
EDO
HOH
7.064
6.670
3.214
CG2
O
CG2
O2
O2
O
VAL S:92 S:92 54.0 0.348 E -119.0 91.1 54.0 0.348 0.0 EDO
EDO
HOH
7.165
7.206
2.654
O
CG2
O
C2
O2
O
6jy3 6 P00428 85.71 5e-64 X-RAY
2019-09-18 VAL F:92 F:92 64.0 0.413 E -126.8 89.7 64.0 0.413 0.0 HOH
5.822
N
O
6jy4 6 P00428 85.71 5e-64 X-RAY
2019-09-18 VAL F:92 F:92 66.0 0.426 E -122.8 93.4 66.0 0.426 0.0 HOH
5.860
N
O
6nkn 6 P00428 85.71 5e-64 X-RAY
2019-03-20 VAL F:92 F:92 43.0 0.277 E -113.5 159.5 43.0 0.277 0.0 HOH
5.809
N
O
VAL S:92 S:92 55.0 0.355 -143.2 73.8 55.0 0.355 0.0 HOH
2.439
C
O
6nmf 6 P00428 85.71 5e-64 X-RAY
2019-03-13 VAL F:92 F:92 54.0 0.348 -104.1 74.5 54.0 0.348 0.0 HOH
6.026
N
O
VAL S:92 S:92 51.0 0.329 E -137.8 134.8 51.0 0.329 0.0 HOH
3.470
C
O
6nmp 6 P00428 85.71 5e-64 X-RAY
2019-03-13 VAL F:92 F:92 58.0 0.374 -127.4 62.9 58.0 0.374 0.0 HOH
2.855
O
O
VAL S:92 S:92 58.0 0.374 -131.6 71.1 58.0 0.374 0.0 HOH
3.820
O
O
7coh 6 P00428 85.71 5e-64 X-RAY
2021-04-07 VAL F:92 F:92 60.0 0.387 E -123.4 82.5 60.0 0.387 0.0 HOH
3.779
CG1
O
VAL S:92 S:92 55.0 0.355 E -122.6 80.3 NA NA NA
7ev7 6 P00428 85.71 5e-64 X-RAY
2021-07-14 VAL F:92 F:92 55.0 0.355 E -120.6 86.5 55.0 0.355 0.0 EDO
HOH
7.321
2.793
CG2
O
O2
O
VAL S:92 S:92 49.0 0.316 E -122.2 88.3 NA NA NA
5xdq 6 P00428 85.11 9e-61 X-RAY
2017-07-12 VAL F:92 F:92 60.0 0.387 E -126.2 90.3 60.0 0.387 0.0 HOH
2.719
O
O
VAL S:92 S:92 43.0 0.277 E -123.4 126.8 NA NA NA
5xdx 6 P00428 85.11 9e-61 X-RAY
2018-02-07 VAL F:92 F:92 52.0 0.335 E -115.8 95.6 52.0 0.335 0.0 EDO
HOH
6.723
4.797
O
N
C1
O
VAL S:92 S:92 41.0 0.265 E -132.6 152.8 NA NA NA
7cp5 6 P00428 85.11 9e-61 X-RAY
2021-07-21 VAL F:92 F:92 57.0 0.368 E -118.3 88.7 57.0 0.368 0.0 EDO
HOH
6.712
2.742
O
O
C1
O
VAL S:92 S:92 52.0 0.335 E -121.2 89.7 52.0 0.335 0.0 EDO
EDO
HOH
7.071
7.387
3.754
O
CG2
CA
C1
O1
O
7d5w 6 P00428 85.11 9e-61 X-RAY
2021-07-21 VAL F:92 F:92 68.0 0.439 E -121.6 88.8 68.0 0.439 0.0 EDO
EDO
HOH
7.398
6.743
2.726
CG2
O
O
O2
C1
O
VAL S:92 S:92 54.0 0.348 E -121.9 93.0 54.0 0.348 0.0 EDO
EDO
HOH
7.084
7.383
2.719
O
CG2
O
C1
O1
O
7d5x 6 P00428 85.11 9e-61 X-RAY
2021-07-21 VAL F:92 F:92 60.0 0.387 E -126.9 86.8 60.0 0.387 0.0 EDO
EDO
HOH
6.801
7.405
2.773
O
CG1
O
C1
O2
O
VAL S:92 S:92 58.0 0.374 E -122.3 92.0 58.0 0.374 0.0 EDO
EDO
EDO
HOH
7.035
7.366
9.155
3.855
O
CG2
CG2
CA
C1
O1
O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p10606-f1 1 P10606 100.0 8e-94 VAL A:123 A:123 43.0 0.277 E -111.4 129.7