Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 113588064 . A C CCDS2102.1:NM_000576.2:c.684ttT>ttG_NP_000567.1:p.228F>L Homo sapiens interleukin 1 beta (IL1B), mRNA.
pdb_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id
alphafold_id
label_asym_id
label_seq_id
label_comp_id
auth_asym_id
auth_seq_id

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5mvz 3 B5BUQ8 98.09 6e-111 X-RAY
2017-02-15 PHE C:136 U:112 0.0 0.0 E -121.2 121.0 0.0 0.0 0.0 HOH
2.566
N
O
PHE F:136 V:112 4.0 0.019 E -119.0 129.1 NA NA NA
7chy 3 P01584 100.0 4e-110 X-RAY
2021-01-13 PHE C:116 I:228 1.0 0.005 -146.5 83.4 1.0 0.005 0.0 HOH
8.703
CD2
O
7chz 3 P01584 100.0 4e-110 X-RAY
2021-01-13 PHE C:116 I:229 1.0 0.005 E -129.7 100.0 1.0 0.005 0.0 HOH
2.923
N
O
1i1b 1 P01584 100.0 4e-110 X-RAY
1990-01-15 PHE A:112 A:112 0.0 0.0 E -116.9 105.8 0.0 0.0 0.0 HOH
2.858
N
O
1iob 1 P01584 100.0 4e-110 NMR
X-RAY
1996-08-17 PHE A:112 A:112 1.0 0.005 E -118.3 103.6 1.0 0.005 0.0 HOH
2.951
N
O
1itb 1 P01584 100.0 4e-110 X-RAY
1998-02-04 PHE A:112 A:112 0.0 0.0 E -125.5 98.6 0.0 0.0 0.0 HOH
1.890
H
O
2i1b 1 P01584 100.0 4e-110 X-RAY
1990-04-15 PHE A:112 A:112 0.0 0.0 E -121.1 102.4 0.0 0.0 0.0 HOH
2.779
N
O
2nvh 1 P01584 100.0 4e-110 X-RAY
2006-12-12 PHE A:112 A:112 0.0 0.0 E -117.5 94.0 0.0 0.0 0.0 HOH
2.842
N
O
4i1b 1 P01584 100.0 4e-110 X-RAY
1990-04-15 PHE A:112 A:112 1.0 0.005 E -114.1 100.6 1.0 0.005 0.0 HOH
2.828
N
O
5bvp 2 P01584 100.0 4e-110 X-RAY
2015-09-02 PHE B:112 I:112 0.0 0.0 E -117.9 99.6 0.0 0.0 0.0 HOH
2.703
N
O
5i1b 1 P01584 100.0 4e-110 X-RAY
1992-01-15 PHE A:112 A:112 0.0 0.0 E -123.5 107.3 0.0 0.0 0.0 HOH
2.862
N
O
5r7w 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -122.7 100.6 0.0 0.0 0.0 HOH
2.842
N
O
5r85 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.4 100.5 0.0 0.0 0.0 HOH
2.824
N
O
5r86 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.8 100.3 0.0 0.0 0.0 GT4
HOH
8.233
2.821
CZ
N
C6
O
5r87 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -120.3 99.8 0.0 0.0 0.0 K0G
HOH
7.335
2.833
CZ
N
C2
O
5r88 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.5 100.0 0.0 0.0 0.0 HOH
2.832
N
O
5r89 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -120.1 97.0 0.0 0.0 0.0 HOH
2.780
N
O
5r8a 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -124.3 96.7 0.0 0.0 0.0 HOH
2.844
N
O
5r8b 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.6 97.8 0.0 0.0 0.0 K34
K34
HOH
8.443
8.131
2.859
CZ
CZ
N
S
S
O
5r8c 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.7 99.1 0.0 0.0 0.0 HOH
2.835
N
O
5r8d 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.0 100.3 0.0 0.0 0.0 HOH
2.841
N
O
5r8e 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.6 99.4 0.0 0.0 0.0 HOH
2.865
N
O
5r8f 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.7 99.7 0.0 0.0 0.0 HOH
2.849
N
O
5r8g 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -123.7 100.0 0.0 0.0 0.0 HOH
2.803
N
O
5r8h 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -120.4 99.8 0.0 0.0 0.0 HOH
2.844
N
O
5r8i 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.7 98.7 0.0 0.0 0.0 HOH
2.846
N
O
5r8j 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -120.3 99.0 0.0 0.0 0.0 HOH
2.821
N
O
5r8k 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.6 97.7 0.0 0.0 0.0 HOH
2.821
N
O
5r8l 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -118.9 100.9 0.0 0.0 0.0 HOH
2.844
N
O
5r8m 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -122.2 101.3 0.0 0.0 0.0 HOH
2.816
N
O
5r8n 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.7 98.2 0.0 0.0 0.0 HOH
2.838
N
O
5r8o 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -121.0 98.9 0.0 0.0 0.0 HOH
2.858
N
O
5r8p 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -120.2 98.4 0.0 0.0 0.0 HOH
2.862
N
O
5r8q 1 P01584 100.0 4e-110 X-RAY
2020-04-22 PHE A:112 A:112 0.0 0.0 E -124.2 98.9 0.0 0.0 0.0 HOH
2.816
N
O
6y8i 1 P01584 100.0 4e-110 X-RAY
2020-06-17 PHE A:112 A:112 0.0 0.0 E -122.3 98.7 0.0 0.0 0.0 OGE
HOH
8.016
2.806
CZ
N
C6
O
6y8m 1 P01584 100.0 4e-110 X-RAY
2020-03-18 PHE A:112 A:112 0.0 0.0 E -117.5 97.7 0.0 0.0 0.0 SX2
SX2
HOH
7.957
8.004
2.686
CZ
CZ
N
C9
O2
O
9ilb 1 P01584 100.0 4e-110 X-RAY
1999-01-06 PHE A:112 A:112 1.0 0.005 E -121.7 109.1 1.0 0.005 0.0 HOH
2.714
N
O
4g6j 1 P01584 100.0 6e-110 X-RAY
2012-12-19 PHE A:113 A:112 1.0 0.005 E -125.2 96.6 1.0 0.005 0.0 HOH
2.804
N
O
3o4o 1 P01584 100.0 8e-110 X-RAY
2010-09-01 PHE A:117 A:112 0.0 0.0 E -132.6 97.7 0.0 0.0 0.0
4dep 1 P01584 100.0 8e-110 X-RAY
2012-03-21 PHE A:117 A:112 2.0 0.01 E -109.5 113.3 2.0 0.01 0.0
PHE D:117 D:112 1.0 0.005 E -105.4 105.7 NA NA NA
1twm 1 P01584 99.35 9e-110 X-RAY
2004-12-07 PHE A:112 A:112 0.0 0.0 E -123.5 105.3 0.0 0.0 0.0 HOH
2.776
N
O
1twe 1 P01584 99.35 9e-110 X-RAY
2004-12-07 PHE A:112 A:112 1.0 0.005 E -121.6 103.7 1.0 0.005 0.0 HOH
2.755
N
O
1t4q 1 P01584 99.35 3e-109 X-RAY
2004-12-07 PHE A:112 A:112 1.0 0.005 E -122.0 105.6 1.0 0.005 0.0 HOH
2.760
N
O
1too 1 P01584 99.35 3e-109 X-RAY
2004-12-07 PHE A:112 A:112 0.0 0.0 E -118.4 104.3 0.0 0.0 0.0 HOH
2.764
N
O
1s0l 1 P01584 99.35 3e-109 X-RAY
2004-03-30 PHE A:112 A:112 1.0 0.005 E -117.6 107.6 1.0 0.005 0.0 HOH
2.779
N
O
21bi 1 P01584 99.35 4e-109 X-RAY
1992-04-15 PHE A:112 A:112 1.0 0.005 E -116.6 98.5 1.0 0.005 0.0
41bi 1 P01584 99.35 4e-109 X-RAY
1992-04-15 PHE A:112 A:112 1.0 0.005 E -115.9 98.1 1.0 0.005 0.0
31bi 1 P01584 99.35 6e-109 X-RAY
1992-04-15 PHE A:112 A:112 1.0 0.005 E -125.6 99.5 1.0 0.005 0.0
1hib 1 P01584 99.35 7e-109 X-RAY
1994-01-31 PHE A:112 A:112 0.0 0.0 E -130.1 107.8 0.0 0.0 0.0 HOH
2.899
N
O
1tp0 1 P01584 98.04 2e-108 X-RAY
2005-02-08 PHE A:112 A:112 1.0 0.005 E -119.4 103.0 1.0 0.005 0.0 HOH
2.940
N
O
4g6m 1 P01584 100.0 6e-108 X-RAY
2012-12-19 PHE A:111 A:112 1.0 0.005 E -121.4 100.4 1.0 0.005 0.0 HOH
2.880
N
O
1l2h 1 P01584 98.69 1e-107 X-RAY
2003-02-04 PHE A:112 A:112 1.0 0.005 E -124.1 101.9 1.0 0.005 0.0 HOH
2.750
N
O
3ltq 1 P01584 90.0 4e-105 X-RAY
2011-02-16 PHE A:130 A:112 0.0 0.0 E -119.9 98.7 0.0 0.0 0.0 HOH
2.942
N
O
3pok 1 P01584 90.36 5e-102 X-RAY
2011-01-19 PHE A:126 A:125 0.0 0.0 E -122.8 104.5 0.0 0.0 0.0 HOH
2.791
N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p01584-f1 1 P01584 100.0 0.0 PHE A:228 A:228 0.0 0.0 E -123.8 93.3