Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 113590240 | . | T | A | CCDS2102.1:NM_000576.2:c.465caA>caT_NP_000567.1:p.155Q>H | Homo sapiens interleukin 1 beta (IL1B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
5mvz | 3 | B5BUQ8 | 98.09 | 6e-111 |
X-RAY |
2017-02-15 | GLN | C:63 | U:39 | 43.0 | 0.239 | -73.1 | 152.1 | 43.0 | 0.239 | 0.0 |
HOH |
2.521 |
O |
O |
|||
GLN | F:63 | V:39 | 39.0 | 0.217 | -91.9 | 151.1 | NA | NA | NA | ||||||||||||||
7chy | 3 | P01584 | 100.0 | 4e-110 |
X-RAY |
2021-01-13 | GLN | C:43 | I:155 | 36.0 | 0.2 | S | -66.1 | 138.5 | 36.0 | 0.2 | 0.0 |
HOH |
2.928 |
O |
O |
||
7chz | 3 | P01584 | 100.0 | 4e-110 |
X-RAY |
2021-01-13 | GLN | C:43 | I:156 | 37.0 | 0.206 | B | -67.9 | 145.1 | 37.0 | 0.206 | 0.0 |
HOH |
2.334 |
OE1 |
O |
||
1i1b | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
1990-01-15 | GLN | A:39 | A:39 | 37.0 | 0.206 | S | -83.9 | 131.9 | 37.0 | 0.206 | 0.0 |
HOH |
2.447 |
OE1 |
O |
||
1iob | 1 | P01584 | 100.0 | 4e-110 |
NMR X-RAY |
1996-08-17 | GLN | A:39 | A:39 | 41.0 | 0.228 | B | -88.2 | 137.0 | 41.0 | 0.228 | 0.0 |
HOH |
3.035 |
OE1 |
O |
||
1itb | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
1998-02-04 | GLN | A:39 | A:39 | 28.0 | 0.156 | B | -75.5 | 143.8 | 28.0 | 0.156 | 0.0 |
HOH |
4.975 |
HE21 |
H1 |
||
2i1b | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
1990-04-15 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -63.6 | 145.6 | 36.0 | 0.2 | 0.0 |
HOH |
2.719 |
O |
O |
||
2nvh | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2006-12-12 | GLN | A:39 | A:39 | 39.0 | 0.217 | S | -67.3 | 150.6 | 39.0 | 0.217 | 0.0 |
HOH |
2.703 |
O |
O |
||
4i1b | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
1990-04-15 | GLN | A:39 | A:39 | 33.0 | 0.183 | S | -96.3 | 141.7 | 33.0 | 0.183 | 0.0 |
HOH |
2.750 |
OE1 |
O |
||
5bvp | 2 | P01584 | 100.0 | 4e-110 |
X-RAY |
2015-09-02 | GLN | B:39 | I:39 | 14.0 | 0.078 | S | -56.8 | 130.1 | 11.0 | 0.061 | 0.017 |
A:None:0.017 |
CL HOH |
4.319 2.583 |
NE2 OE1 |
CL O |
|
5i1b | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
1992-01-15 | GLN | A:39 | A:39 | 36.0 | 0.2 | S | -58.0 | 138.6 | 36.0 | 0.2 | 0.0 |
HOH |
2.742 |
O |
O |
||
5r7w | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 39.0 | 0.217 | B | -61.6 | 152.1 | 39.0 | 0.217 | 0.0 |
HOH |
2.675 |
O |
O |
||
5r85 | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 38.0 | 0.211 | S | -66.8 | 151.6 | 38.0 | 0.211 | 0.0 |
HOH |
2.663 |
O |
O |
||
5r86 | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 37.0 | 0.206 | B | -64.9 | 146.6 | 37.0 | 0.206 | 0.0 |
HOH |
2.647 |
O |
O |
||
5r87 | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -69.3 | 150.7 | 36.0 | 0.2 | 0.0 |
HOH |
2.657 |
O |
O |
||
5r88 | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 37.0 | 0.206 | B | -65.1 | 151.8 | 37.0 | 0.206 | 0.0 |
HOH |
2.636 |
O |
O |
||
5r89 | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 40.0 | 0.222 | S | -64.6 | 149.8 | 40.0 | 0.222 | 0.0 |
HOH |
2.644 |
O |
O |
||
5r8a | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | S | -59.1 | 147.4 | 36.0 | 0.2 | 0.0 |
S7G HOH |
3.719 2.620 |
O O |
C3 O |
||
5r8b | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -66.3 | 147.7 | 36.0 | 0.2 | 0.0 |
HOH |
2.616 |
O |
O |
||
5r8c | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 46.0 | 0.256 | B | -72.9 | 144.4 | 46.0 | 0.256 | 0.0 |
M25 HOH |
3.924 2.950 |
O NE2 |
C6 O |
||
5r8d | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 38.0 | 0.211 | S | -64.8 | 149.1 | 38.0 | 0.211 | 0.0 |
HOH |
2.627 |
O |
O |
||
5r8e | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 38.0 | 0.211 | B | -65.3 | 152.9 | 38.0 | 0.211 | 0.0 |
HOH |
2.698 |
O |
O |
||
5r8f | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -67.4 | 151.4 | 36.0 | 0.2 | 0.0 |
K3Y HOH |
3.603 2.635 |
O O |
C7 O |
||
5r8g | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 50.0 | 0.278 | S | -64.2 | 135.0 | 50.0 | 0.278 | 0.0 |
S7V HOH |
3.581 2.497 |
O O |
C3 O |
||
5r8h | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 39.0 | 0.217 | S | -68.1 | 151.2 | 39.0 | 0.217 | 0.0 |
T91 HOH |
2.495 2.790 |
O OE1 |
N1 O |
||
5r8i | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | S | -66.6 | 150.1 | 36.0 | 0.2 | 0.0 |
HOH |
2.620 |
O |
O |
||
5r8j | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 29.0 | 0.161 | S | -67.1 | 142.7 | 29.0 | 0.161 | 0.0 |
S8D HOH |
3.508 2.500 |
O O |
C7 O |
||
5r8k | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 37.0 | 0.206 | S | -65.1 | 149.0 | 37.0 | 0.206 | 0.0 |
S8D HOH |
3.295 2.649 |
O O |
C7 O |
||
5r8l | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 35.0 | 0.194 | B | -68.1 | 150.4 | 35.0 | 0.194 | 0.0 |
HOH |
2.539 |
O |
O |
||
5r8m | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -65.1 | 154.3 | 36.0 | 0.2 | 0.0 |
HOH |
2.629 |
O |
O |
||
5r8n | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 37.0 | 0.206 | B | -67.3 | 151.3 | 37.0 | 0.206 | 0.0 |
HOH |
2.599 |
O |
O |
||
5r8o | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -65.4 | 150.2 | 36.0 | 0.2 | 0.0 |
HOH |
2.638 |
O |
O |
||
5r8p | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 36.0 | 0.2 | B | -66.7 | 151.6 | 36.0 | 0.2 | 0.0 |
HOH |
2.595 |
O |
O |
||
5r8q | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-04-22 | GLN | A:39 | A:39 | 40.0 | 0.222 | S | -66.5 | 151.3 | 40.0 | 0.222 | 0.0 |
HOH |
2.682 |
O |
O |
||
6y8i | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-06-17 | GLN | A:39 | A:39 | 35.0 | 0.194 | B | -70.7 | 151.9 | 35.0 | 0.194 | 0.0 |
OGE HOH |
9.018 2.715 |
NE2 O |
O O |
||
6y8m | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
2020-03-18 | GLN | A:39 | A:39 | 37.0 | 0.206 | B | -72.3 | 148.1 | 37.0 | 0.206 | 0.0 |
SX2 HOH |
9.007 2.504 |
OE1 O |
O2 O |
||
9ilb | 1 | P01584 | 100.0 | 4e-110 |
X-RAY |
1999-01-06 | GLN | A:39 | A:39 | 41.0 | 0.228 | S | -72.6 | 150.9 | 41.0 | 0.228 | 0.0 |
HOH |
2.764 |
NE2 |
O |
||
4g6j | 1 | P01584 | 100.0 | 6e-110 |
X-RAY |
2012-12-19 | GLN | A:40 | A:39 | 25.0 | 0.139 | S | -62.4 | 133.2 | 20.0 | 0.111 | 0.028 |
B:None:0.028 |
HOH |
2.737 |
OE1 |
O |
|
3o4o | 1 | P01584 | 100.0 | 8e-110 |
X-RAY |
2010-09-01 | GLN | A:44 | A:39 | 22.0 | 0.122 | S | -60.6 | 130.5 | 22.0 | 0.122 | 0.0 | ||||||
4dep | 1 | P01584 | 100.0 | 8e-110 |
X-RAY |
2012-03-21 | GLN | A:44 | A:39 | 41.0 | 0.228 | B | -74.5 | 129.0 | 40.0 | 0.222 | 0.006 |
B:P14778:0.006 |
|||||
GLN | D:44 | D:39 | 38.0 | 0.211 | B | -65.5 | 131.6 | NA | NA | NA | |||||||||||||
1twm | 1 | P01584 | 99.35 | 9e-110 |
X-RAY |
2004-12-07 | GLN | A:39 | A:39 | 34.0 | 0.189 | B | -59.0 | 145.1 | 34.0 | 0.189 | 0.0 |
HOH |
2.650 |
O |
O |
||
1twe | 1 | P01584 | 99.35 | 9e-110 |
X-RAY |
2004-12-07 | GLN | A:39 | A:39 | 34.0 | 0.189 | B | -58.6 | 144.4 | 34.0 | 0.189 | 0.0 |
HOH |
2.646 |
O |
O |
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1t4q | 1 | P01584 | 99.35 | 3e-109 |
X-RAY |
2004-12-07 | GLN | A:39 | A:39 | 36.0 | 0.2 | S | -62.3 | 145.7 | 36.0 | 0.2 | 0.0 |
HOH |
2.604 |
O |
O |
||
1too | 1 | P01584 | 99.35 | 3e-109 |
X-RAY |
2004-12-07 | GLN | A:39 | A:39 | 36.0 | 0.2 | S | -62.0 | 142.7 | 36.0 | 0.2 | 0.0 |
HOH |
2.719 |
O |
O |
||
1s0l | 1 | P01584 | 99.35 | 3e-109 |
X-RAY |
2004-03-30 | GLN | A:39 | A:39 | 31.0 | 0.172 | S | -49.2 | 148.7 | 31.0 | 0.172 | 0.0 |
HOH |
2.558 |
OE1 |
O |
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21bi | 1 | P01584 | 99.35 | 4e-109 |
X-RAY |
1992-04-15 | GLN | A:39 | A:39 | 34.0 | 0.189 | S | -94.0 | 141.6 | 34.0 | 0.189 | 0.0 | ||||||
41bi | 1 | P01584 | 99.35 | 4e-109 |
X-RAY |
1992-04-15 | GLN | A:39 | A:39 | 39.0 | 0.217 | -95.8 | 139.2 | 39.0 | 0.217 | 0.0 | |||||||
31bi | 1 | P01584 | 99.35 | 6e-109 |
X-RAY |
1992-04-15 | GLN | A:39 | A:39 | 33.0 | 0.183 | S | -87.3 | 137.7 | 33.0 | 0.183 | 0.0 | ||||||
1hib | 1 | P01584 | 99.35 | 7e-109 |
X-RAY |
1994-01-31 | GLN | A:39 | A:39 | 9.0 | 0.05 | -80.7 | 150.4 | 9.0 | 0.05 | 0.0 |
HOH |
2.626 |
OE1 |
O |
|||
1tp0 | 1 | P01584 | 98.04 | 2e-108 |
X-RAY |
2005-02-08 | GLN | A:39 | A:39 | 31.0 | 0.172 | S | -55.9 | 141.1 | 31.0 | 0.172 | 0.0 |
HOH |
2.677 |
OE1 |
O |
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4g6m | 1 | P01584 | 100.0 | 6e-108 |
X-RAY |
2012-12-19 | GLN | A:38 | A:39 | 37.0 | 0.206 | B | -56.7 | 143.4 | 37.0 | 0.206 | 0.0 |
HOH |
2.712 |
O |
O |
||
1l2h | 1 | P01584 | 98.69 | 1e-107 |
X-RAY |
2003-02-04 | GLN | A:39 | A:39 | 32.0 | 0.178 | S | -76.6 | 148.9 | 32.0 | 0.178 | 0.0 |
HOH |
2.500 |
O |
O |
||
3ltq | 1 | P01584 | 90.0 | 4e-105 |
X-RAY |
2011-02-16 | GLN | A:40 | A:39 | 32.0 | 0.178 | B | -54.1 | 127.8 | 32.0 | 0.178 | 0.0 |
HOH |
2.832 |
O |
O |
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3pok | 1 | P01584 | 90.36 | 5e-102 |
X-RAY |
2011-01-19 | GLN | A:40 | A:39 | 34.0 | 0.189 | B | -67.8 | 145.4 | 34.0 | 0.189 | 0.0 |
HOH |
2.674 |
O |
O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p01584-f1 | 1 | P01584 | 100.0 | 0.0 | GLN | A:155 | A:155 | 18.0 | 0.1 | B | -62.3 | 134.0 |