Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 128605698 . G A CCDS2151.1:NM_004805.3:c.412Cgc>Tgc_NP_004796.1:p.138R>C Homo sapiens RNA polymerase II subunit D (POLR2D), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2c35 1 O15514 100.0 3e-102 X-RAY
 2005-11-18 ARG A:148 A:138 46.0 0.204 -45.5 130.4 46.0 0.204 0.0 HOH
 5.684
 NH1
 O
ARG C:148 C:138 45.0 0.2 -46.0 130.7 NA NA NA
ARG E:148 E:138 93.0 0.413 -51.7 122.9 NA NA NA
ARG G:148 G:138 94.0 0.418 -52.1 122.6 NA NA NA
5iy6 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 51.0 0.227 S -57.1 151.7 51.0 0.227 0.0
5iy7 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 49.0 0.218 -55.3 133.3 49.0 0.218 0.0
5iy8 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 88.0 0.391 -53.4 159.0 88.0 0.391 0.0
5iy9 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 89.0 0.396 -50.0 144.6 89.0 0.396 0.0
5iya 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 51.0 0.227 S -57.1 151.7 51.0 0.227 0.0
5iyb 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 50.0 0.222 -55.4 133.3 50.0 0.222 0.0
5iyc 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 87.0 0.387 -53.3 159.0 87.0 0.387 0.0
5iyd 4 O15514 100.0 5e-102 EM
 2016-05-18 ARG D:138 D:138 85.0 0.378 -50.0 144.7 85.0 0.378 0.0
6drd 4 O15514 100.0 5e-102 EM
 2019-06-12 ARG D:138 D:138 35.0 0.156 -91.8 137.6 35.0 0.156 0.0
6exv 4 A0A287ADR4 100.0 5e-102 EM
 2018-03-21 ARG D:138 D:138 86.0 0.382 S -72.7 111.6 86.0 0.382 0.0
6gmh 4 A0A287ADR4 100.0 5e-102 EM
 2018-08-22 ARG D:138 D:138 115.0 0.511 -62.8 138.1 115.0 0.511 0.0
6gml 20 A0A287ADR4 100.0 5e-102 EM
 2018-09-05 ARG T:138 D:138 37.0 0.164 -80.6 122.8 34.0 0.151 0.013 U:I3LJZ9:0.013
6o9l 4 O15514 100.0 5e-102 EM
 2019-05-29 ARG D:138 D:138 44.0 0.196 -72.5 120.4 44.0 0.196 0.0
6ted 4 A0A287ADR4 100.0 5e-102 EM
 2020-07-22 ARG D:138 D:138 102.0 0.453 -73.2 123.5 92.0 0.409 0.044 G:I3LJZ9:0.044
6xre 4 O15514 100.0 5e-102 EM
 2021-03-24 ARG D:138 D:138 26.0 0.116 -76.9 156.9 22.0 0.098 0.018 G:P62487:0.018
7b0y 4 A0A287ADR4 100.0 5e-102 EM
 2021-01-13 ARG D:138 D:138 55.0 0.244 -73.3 136.1 55.0 0.244 0.0
7edx 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 ARG EA:138 r:138 48.0 0.213 S -67.5 117.6 48.0 0.213 0.0
7eg7 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 ARG EA:138 r:138 49.0 0.218 S -67.6 117.6 49.0 0.218 0.0
7eg8 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 ARG EA:138 r:138 49.0 0.218 S -67.5 117.7 47.0 0.209 0.009 HA:A0A4X1VKG7:0.009
7eg9 27 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 ARG GA:138 r:138 47.0 0.209 S -67.6 117.7 47.0 0.209 0.0
7ega 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 ARG EA:138 r:138 49.0 0.218 S -67.4 117.6 49.0 0.218 0.0
7egb 37 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 ARG QA:138 r:138 49.0 0.218 S -67.5 117.5 49.0 0.218 0.0
7egc 37 A0A481BYI6 100.0 5e-102 EM
 2021-05-12 ARG QA:138 r:138 48.0 0.213 S -67.5 117.6 48.0 0.213 0.0
7ena 13 A0A481BYI6 100.0 5e-102 EM
 2021-05-26 ARG M:138 PD:138 74.0 0.329 H -62.5 -23.1 74.0 0.329 0.0
7enc 58 A0A481BYI6 100.0 5e-102 EM
 2021-05-26 ARG LB:138 PD:138 71.0 0.316 H -62.8 -40.0 70.0 0.311 0.005 O:Q15528:0.004
7f4g 12 A0A481BYI6 100.0 5e-102 EM
 2021-07-07 ARG L:138 D:138 70.0 0.311 -65.0 108.7 70.0 0.311 0.0
7lbm 8 O15514 100.0 5e-102 EM
 2021-03-24 ARG H:138 D:138 80.0 0.356 H -74.9 -9.5 37.0 0.164 0.192 QA:Q15528:0.191
7nvr 14 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG N:138 D:138 84.0 0.373 H -62.7 -40.9 61.0 0.271 0.102 OA:Q15528:0.102
7nvs 4 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG D:138 D:138 42.0 0.187 S -59.5 139.2 42.0 0.187 0.0
7nvt 4 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG D:138 D:138 42.0 0.187 S -59.5 139.2 42.0 0.187 0.0
7nvu 4 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG D:138 D:138 47.0 0.209 S -59.2 138.5 47.0 0.209 0.0
7nvy 12 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG L:138 D:138 45.0 0.2 S -62.5 144.4 45.0 0.2 0.0
7nvz 12 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG L:138 D:138 46.0 0.204 S -61.3 142.6 46.0 0.204 0.0
7nw0 12 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 ARG L:138 D:138 46.0 0.204 S -58.9 138.6 46.0 0.204 0.0
7oo3 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 ARG D:138 D:138 52.0 0.231 -71.3 134.8 52.0 0.231 0.0
7oob 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-13 ARG D:138 D:138 52.0 0.231 -71.3 134.8 52.0 0.231 0.0
7oop 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 ARG D:138 D:138 83.0 0.369 -61.1 133.1 18.0 0.08 0.289 M:Q7KZ85:0.289
7opc 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-13 ARG D:138 D:138 87.0 0.387 -69.8 120.3 27.0 0.12 0.267 M:Q7KZ85:0.267
7opd 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 ARG D:138 D:138 87.0 0.387 -69.8 120.3 27.0 0.12 0.267 M:Q7KZ85:0.267
7ozn 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 ARG D:138 D:138 58.0 0.258 -66.3 142.8 37.0 0.164 0.094 N:A0A0B8RVL1:0.093
ARG P:138 P:138 59.0 0.262 -66.3 142.8 37.0 0.164 0.098 B:A0A0B8RVL1:0.098
7ozo 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 ARG D:138 D:138 99.0 0.44 S -60.6 134.4 75.0 0.333 0.107 N:A0A0B8RVL1:0.107
ARG P:138 P:138 100.0 0.444 S -60.6 134.4 75.0 0.333 0.111 B:A0A0B8RVL1:0.111
7ozp 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 ARG D:138 D:138 60.0 0.267 -63.0 137.9 39.0 0.173 0.094 N:A0A0B8RVL1:0.093
ARG P:138 P:138 61.0 0.271 -63.1 138.0 39.0 0.173 0.098 B:A0A0B8RVL1:0.098
7pks 4 A0A287ADR4 100.0 5e-102 EM
 2021-12-08 ARG D:138 D:138 67.0 0.298 -87.2 150.1 67.0 0.298 0.0
5flm 4 Q1JQ91 99.3 2e-101 EM
 2016-01-20 ARG D:138 D:138 42.0 0.187 -59.8 133.2 42.0 0.187 0.0
5oik 4 Q1JQ91 99.3 2e-101 EM
 2017-09-13 ARG D:138 D:138 45.0 0.2 -46.1 131.1 45.0 0.2 0.0
7okx 4 A0A287ADR4 100.0 2e-101 EM
 2021-07-14 ARG D:180 D:180 121.0 0.538 -69.1 360.0 121.0 0.538 0.0
7oky 4 A0A287ADR4 100.0 2e-101 EM
 2021-07-14 ARG D:180 D:180 119.0 0.529 -69.1 360.0 119.0 0.529 0.0
7ol0 4 A0A287ADR4 100.0 2e-101 EM
 2021-07-14 ARG D:180 D:180 114.0 0.507 -62.7 360.0 114.0 0.507 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o15514-f1 1 O15514 100.0 2e-102 ARG A:138 A:138 58.0 0.258 H -69.0 -31.3