Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 128608219 . A C CCDS2151.1:NM_004805.3:c.295Tgt>Ggt_NP_004796.1:p.99C>G Homo sapiens RNA polymerase II subunit D (POLR2D), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2c35 1 O15514 100.0 3e-102 X-RAY
 2005-11-18 CYS A:109 A:99 29.0 0.215 H -72.0 -37.4 4.0 0.03 0.185 B:P62487:0.185
 HOH
 3.924
 SG
 O
CYS C:109 C:99 28.0 0.207 H -70.1 -37.5 NA NA NA
CYS E:109 E:99 24.0 0.178 H -67.1 -43.7 NA NA NA
CYS G:109 G:99 25.0 0.185 H -66.4 -45.1 NA NA NA
5iy6 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 22.0 0.163 H -73.3 -39.0 11.0 0.081 0.082 G:P62487:0.081
5iy7 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 35.0 0.259 H -73.4 -40.2 4.0 0.03 0.229 G:P62487:0.23
5iy8 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 30.0 0.222 H -73.6 -41.6 7.0 0.052 0.17 G:P62487:0.17
5iy9 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 29.0 0.215 H -72.7 -38.3 8.0 0.059 0.156 G:P62487:0.156
5iya 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 22.0 0.163 H -73.2 -39.0 12.0 0.089 0.074 G:P62487:0.074
5iyb 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 34.0 0.252 H -73.5 -40.3 4.0 0.03 0.222 G:P62487:0.222
5iyc 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 30.0 0.222 H -73.6 -41.6 8.0 0.059 0.163 G:P62487:0.163
5iyd 4 O15514 100.0 5e-102 EM
 2016-05-18 CYS D:99 D:99 30.0 0.222 H -72.7 -38.3 8.0 0.059 0.163 G:P62487:0.163
6drd 4 O15514 100.0 5e-102 EM
 2019-06-12 CYS D:99 D:99 8.0 0.059 I -71.7 -34.4 8.0 0.059 0.0
6exv 4 A0A287ADR4 100.0 5e-102 EM
 2018-03-21 CYS D:99 D:99 27.0 0.2 H -73.0 -44.8 11.0 0.081 0.119 G:I3LJZ9:0.119
6gmh 4 A0A287ADR4 100.0 5e-102 EM
 2018-08-22 CYS D:99 D:99 40.0 0.296 H -65.8 -36.5 12.0 0.089 0.207 G:I3LJZ9:0.207
6gml 20 A0A287ADR4 100.0 5e-102 EM
 2018-09-05 CYS T:99 D:99 27.0 0.2 H -71.3 -33.7 4.0 0.03 0.17 U:I3LJZ9:0.17
6o9l 4 O15514 100.0 5e-102 EM
 2019-05-29 CYS D:99 D:99 29.0 0.215 H -73.5 -24.2 13.0 0.096 0.119 G:P62487:0.119
6ted 4 A0A287ADR4 100.0 5e-102 EM
 2020-07-22 CYS D:99 D:99 30.0 0.222 H -62.2 -30.5 14.0 0.104 0.118 G:I3LJZ9:0.119
6xre 4 O15514 100.0 5e-102 EM
 2021-03-24 CYS D:99 D:99 16.0 0.119 H -62.9 -54.6 1.0 0.007 0.112 G:P62487:0.111
7b0y 4 A0A287ADR4 100.0 5e-102 EM
 2021-01-13 CYS D:99 D:99 49.0 0.363 H -65.0 -34.2 11.0 0.081 0.282 G:I3LJZ9:0.281
7edx 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 CYS EA:99 r:99 40.0 0.296 H -70.6 -43.7 25.0 0.185 0.111 MA:A0A4X1VKG7:0.111
7eg7 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 CYS EA:99 r:99 40.0 0.296 H -70.5 -43.7 25.0 0.185 0.111 MA:A0A4X1VKG7:0.111
7eg8 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 CYS EA:99 r:99 39.0 0.289 H -70.5 -43.8 5.0 0.037 0.252 HA:A0A4X1VKG7:0.252
7eg9 27 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 CYS GA:99 r:99 40.0 0.296 H -70.5 -43.7 11.0 0.081 0.215 OA:A0A4X1VKG7:0.215
7ega 25 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 CYS EA:99 r:99 38.0 0.281 H -70.5 -43.7 9.0 0.067 0.214 OA:A0A4X1VKG7:0.215
7egb 37 A0A481BYI6 100.0 5e-102 EM
 2021-05-05 CYS QA:99 r:99 40.0 0.296 H -70.4 -43.6 11.0 0.081 0.215 TA:A0A4X1VKG7:0.215
7egc 37 A0A481BYI6 100.0 5e-102 EM
 2021-05-12 CYS QA:99 r:99 40.0 0.296 H -70.6 -43.6 11.0 0.081 0.215 TA:A0A4X1VKG7:0.215
7ena 13 A0A481BYI6 100.0 5e-102 EM
 2021-05-26 CYS M:99 PD:99 42.0 0.311 H -64.0 -46.4 1.0 0.007 0.304 P:A0A4X1VKG7:0.304
7enc 58 A0A481BYI6 100.0 5e-102 EM
 2021-05-26 CYS LB:99 PD:99 21.0 0.156 H -63.3 -41.3 0.0 0.0 0.156 OB:A0A4X1VKG7:0.156
7f4g 12 A0A481BYI6 100.0 5e-102 EM
 2021-07-07 CYS L:99 D:99 16.0 0.119 H -71.3 -31.3 1.0 0.007 0.112 M:A0A4X1VKG7:0.111
7lbm 8 O15514 100.0 5e-102 EM
 2021-03-24 CYS H:99 D:99 14.0 0.104 H -68.2 -42.4 3.0 0.022 0.082 K:P62487:0.081
7nvr 14 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS N:99 D:99 20.0 0.148 H -65.5 -44.8 20.0 0.148 0.0
7nvs 4 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS D:99 D:99 26.0 0.193 H -64.5 -40.7 3.0 0.022 0.171 G:I3LJZ9:0.17
7nvt 4 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS D:99 D:99 26.0 0.193 H -64.4 -40.6 4.0 0.03 0.163 G:I3LJZ9:0.163
7nvu 4 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS D:99 D:99 31.0 0.23 H -63.1 -42.3 15.0 0.111 0.119 G:I3LJZ9:0.119
7nvy 12 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS L:99 D:99 24.0 0.178 H -62.0 -42.1 5.0 0.037 0.141 O:I3LJZ9:0.141
7nvz 12 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS L:99 D:99 24.0 0.178 H -62.7 -41.5 5.0 0.037 0.141 O:I3LJZ9:0.141
7nw0 12 A0A287ADR4 100.0 5e-102 EM
 2021-05-05 CYS L:99 D:99 31.0 0.23 H -63.0 -42.3 17.0 0.126 0.104 O:I3LJZ9:0.104
7oo3 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 CYS D:99 D:99 49.0 0.363 H -64.7 -41.7 11.0 0.081 0.282 G:I3LJZ9:0.281
7oob 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-13 CYS D:99 D:99 50.0 0.37 H -64.7 -41.7 11.0 0.081 0.289 G:I3LJZ9:0.289
7oop 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 CYS D:99 D:99 25.0 0.185 H -65.7 -51.8 6.0 0.044 0.141 G:I3LJZ9:0.141
7opc 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-13 CYS D:99 D:99 29.0 0.215 H -68.2 -43.8 3.0 0.022 0.193 G:I3LJZ9:0.193
7opd 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 CYS D:99 D:99 29.0 0.215 H -68.2 -43.8 3.0 0.022 0.193 G:I3LJZ9:0.193
7ozn 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 CYS D:99 D:99 33.0 0.244 H -63.1 -45.2 5.0 0.037 0.207 G:I3LJZ9:0.207
CYS P:99 P:99 34.0 0.252 H -63.0 -45.3 6.0 0.044 0.208 S:I3LJZ9:0.207
7ozo 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 CYS D:99 D:99 31.0 0.23 H -64.1 -43.1 6.0 0.044 0.186 G:I3LJZ9:0.185
CYS P:99 P:99 31.0 0.23 H -64.0 -43.2 5.0 0.037 0.193 S:I3LJZ9:0.193
7ozp 4 A0A287ADR4 100.0 5e-102 EM
 2021-10-06 CYS D:99 D:99 32.0 0.237 H -64.0 -42.9 7.0 0.052 0.185 G:I3LJZ9:0.185
CYS P:99 P:99 32.0 0.237 H -64.1 -42.9 7.0 0.052 0.185 S:I3LJZ9:0.185
7pks 4 A0A287ADR4 100.0 5e-102 EM
 2021-12-08 CYS D:99 D:99 28.0 0.207 H -64.8 -42.0 19.0 0.141 0.066 G:I3LJZ9:0.067
5flm 4 Q1JQ91 99.3 2e-101 EM
 2016-01-20 CYS D:99 D:99 25.0 0.185 H -66.2 -46.6 4.0 0.03 0.155 G:Q5E9B8:0.156
5oik 4 Q1JQ91 99.3 2e-101 EM
 2017-09-13 CYS D:99 D:99 30.0 0.222 H -71.3 -37.5 3.0 0.022 0.2 G:Q5E9B8:0.2
7okx 4 A0A287ADR4 100.0 2e-101 EM
 2021-07-14 CYS D:141 D:141 35.0 0.259 S -101.9 3.9 6.0 0.044 0.215 G:I3LJZ9:0.215
7oky 4 A0A287ADR4 100.0 2e-101 EM
 2021-07-14 CYS D:141 D:141 35.0 0.259 S -102.0 3.9 6.0 0.044 0.215 G:I3LJZ9:0.215
7ol0 4 A0A287ADR4 100.0 2e-101 EM
 2021-07-14 CYS D:141 D:141 38.0 0.281 T -102.5 10.4 10.0 0.074 0.207 G:I3LJZ9:0.207

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o15514-f1 1 O15514 100.0 2e-102 CYS A:99 A:99 24.0 0.178 H -63.5 -49.5