Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 138758494 | . | T | A | CCDS2181.1:NM_006895.2:c.197aTt>aAt_NP_008826.1:p.66I>N | Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1jqd | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2002-08-06 | ILE | A:66 | A:66 | 18.0 | 0.103 | H | -68.7 | -34.8 | 18.0 | 0.103 | 0.0 |
SAH HOH |
3.463 2.665 |
CG1 N |
O O |
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| ILE | B:66 | B:66 | 1.0 | 0.006 | H | -65.0 | -35.8 | NA | NA | NA | |||||||||||||
| 2aot | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | ILE | A:66 | A:66 | 2.0 | 0.011 | H | -65.5 | -37.5 | 2.0 | 0.011 | 0.0 |
SAH HOH |
3.654 2.855 |
CG1 N |
O O |
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| 2aot | 2 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | ILE | B:66 | B:66 | 6.0 | 0.034 | H | -63.1 | -42.4 | NA | NA | NA | ||||||
| 2aou | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | ILE | A:66 | A:66 | 18.0 | 0.103 | H | -80.9 | -33.9 | 18.0 | 0.103 | 0.0 |
CQA HOH |
9.743 2.907 |
CG1 N |
C11 O |
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| 2aou | 2 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | ILE | B:66 | B:66 | 13.0 | 0.074 | H | -67.3 | -43.0 | NA | NA | NA | ||||||
| 2aov | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | ILE | A:66 | A:66 | 14.0 | 0.08 | H | -63.9 | -37.7 | 14.0 | 0.08 | 0.0 |
HOH |
2.898 |
N |
O |
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| ILE | B:66 | B:66 | 17.0 | 0.097 | H | -83.8 | -31.2 | NA | NA | NA | |||||||||||||
| 2aox | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | ILE | A:66 | A:66 | 3.0 | 0.017 | H | -77.7 | -39.1 | 3.0 | 0.017 | 0.0 |
THA HOH |
8.925 7.202 |
CG1 N |
C6 O |
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| ILE | B:66 | B:66 | 2.0 | 0.011 | H | -77.1 | -40.5 | NA | NA | NA | |||||||||||||
| 1jqe | 1 | P50135 | 99.66 | 0.0 |
X-RAY |
2002-08-06 | ILE | A:66 | A:66 | 3.0 | 0.017 | H | -67.7 | -40.9 | 3.0 | 0.017 | 0.0 |
SAH HOH |
4.235 2.971 |
CG1 N |
OXT O |
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| ILE | B:66 | B:66 | 2.0 | 0.011 | H | -64.2 | -39.6 | NA | NA | NA | |||||||||||||
| 2aow | 1 | P50135 | 99.66 | 0.0 |
X-RAY |
2005-09-13 | ILE | A:66 | A:66 | 1.0 | 0.006 | H | -82.5 | -40.0 | 1.0 | 0.006 | 0.0 |
THA HOH |
8.868 7.499 |
CG1 CG2 |
C6 O |
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| ILE | B:66 | B:66 | 1.0 | 0.006 | H | -81.6 | -40.2 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
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| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50135-f1 | 1 | P50135 | 100.0 | 0.0 | ILE | A:66 | A:66 | 16.0 | 0.091 | H | -74.2 | -38.4 | |