Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 138771492 | . | T | A | CCDS2181.1:NM_006895.2:c.671aTg>aAg_NP_008826.1:p.224M>K | Homo sapiens histamine N-methyltransferase (HNMT), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1jqd | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2002-08-06 | MET | A:224 | A:224 | 0.0 | 0.0 | E | -133.6 | 118.4 | 0.0 | 0.0 | 0.0 |
HSM HOH |
7.152 6.438 |
SD C |
N O |
||
| MET | B:224 | B:224 | 0.0 | 0.0 | E | -128.4 | 109.0 | NA | NA | NA | |||||||||||||
| 2aot | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | MET | A:224 | A:224 | 2.0 | 0.011 | E | -124.5 | 108.6 | 2.0 | 0.011 | 0.0 |
2PM HOH |
7.393 6.042 |
SD N |
C14 O |
||
| 2aot | 2 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | MET | B:224 | B:224 | 0.0 | 0.0 | E | -140.7 | 105.3 | NA | NA | NA | ||||||
| 2aou | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | MET | A:224 | A:224 | 0.0 | 0.0 | E | -122.6 | 114.5 | 0.0 | 0.0 | 0.0 |
CQA HOH |
7.916 3.784 |
SD N |
C17 O |
||
| 2aou | 2 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | MET | B:224 | B:224 | 0.0 | 0.0 | E | -120.6 | 115.1 | NA | NA | NA | ||||||
| 2aov | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | MET | A:224 | A:224 | 2.0 | 0.011 | E | -137.4 | 110.1 | 2.0 | 0.011 | 0.0 |
C2M HOH |
7.823 8.055 |
SD SD |
C12 O |
||
| MET | B:224 | B:224 | 0.0 | 0.0 | E | -124.1 | 108.0 | NA | NA | NA | |||||||||||||
| 2aox | 1 | P50135 | 100.0 | 0.0 |
X-RAY |
2005-09-13 | MET | A:224 | A:224 | 0.0 | 0.0 | E | -133.5 | 109.3 | 0.0 | 0.0 | 0.0 |
THA |
7.419 |
SD |
N15 |
||
| MET | B:224 | B:224 | 0.0 | 0.0 | E | -134.0 | 110.2 | NA | NA | NA | |||||||||||||
| 1jqe | 1 | P50135 | 99.66 | 0.0 |
X-RAY |
2002-08-06 | MET | A:224 | A:224 | 0.0 | 0.0 | E | -116.7 | 115.9 | 0.0 | 0.0 | 0.0 |
QUN HOH |
7.831 4.234 |
SD C |
C21 O |
||
| MET | B:224 | B:224 | 2.0 | 0.011 | E | -129.6 | 88.8 | NA | NA | NA | |||||||||||||
| 2aow | 1 | P50135 | 99.66 | 0.0 |
X-RAY |
2005-09-13 | MET | A:224 | A:224 | 0.0 | 0.0 | E | -123.3 | 115.7 | 0.0 | 0.0 | 0.0 |
THA |
7.328 |
SD |
N15 |
||
| MET | B:224 | B:224 | 0.0 | 0.0 | E | -123.6 | 116.5 | NA | NA | NA | |||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p50135-f1 | 1 | P50135 | 100.0 | 0.0 | MET | A:224 | A:224 | 0.0 | 0.0 | E | -113.9 | 119.1 | |