Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr2 | 203071998 | . | G | A | CCDS2352.1:NM_001005781.1:c.284aCg>aTg_NP_001005781.1:p.95T>M | Homo sapiens small ubiquitin-like modifier 1 (SUMO1), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 2las | 1 | P63165 | 100.0 | 1e-71 |
NMR |
2011-12-14 | THR | A:95 | A:95 | 130.0 | 0.929 | -146.1 | 166.4 | 130.0 | 0.929 | 0.0 | |||||||
| 6jxu | 1 | A0A024R3Z2 | 100.0 | 1e-71 |
NMR |
2020-02-05 | THR | A:95 | A:95 | 108.0 | 0.771 | S | -78.3 | -34.0 | 108.0 | 0.771 | 0.0 | ||||||
| 6jxv | 1 | A0A024R3Z2 | 100.0 | 1e-71 |
NMR |
2020-02-05 | THR | A:95 | A:95 | 100.0 | 0.714 | T | -74.4 | -25.4 | 100.0 | 0.714 | 0.0 | ||||||
| 6xog | 3 | P63165 | 100.0 | 1e-71 |
X-RAY |
2021-03-10 | THR | C:95 | C:95 | 128.0 | 0.914 | -121.6 | 2.1 | 36.0 | 0.257 | 0.657 |
B:Q9UBT2:0.657 |
SO4 VAY HOH |
9.265 6.126 2.800 |
O O OG1 |
O4 N37 O |
||
| 6xoh | 3 | P63165 | 100.0 | 1e-71 |
X-RAY |
2021-03-24 | THR | C:95 | C:95 | 132.0 | 0.943 | -126.0 | -4.3 | 38.0 | 0.271 | 0.672 |
B:Q9UBT2:0.671 |
SO4 VB7 HOH |
8.966 6.133 4.067 |
O O CG2 |
O4 N34 O |
||
| 6xoi | 3 | P63165 | 100.0 | 1e-71 |
X-RAY |
2021-03-24 | THR | C:95 | C:95 | 134.0 | 0.957 | -122.5 | -2.8 | 39.0 | 0.279 | 0.678 |
B:Q9UBT2:0.679 |
SO4 VBA HOH |
9.298 6.178 2.810 |
O O OG1 |
O4 N32 O |
||
| 2n1a | 1 | P63165 | 100.0 | 1e-71 |
NMR |
2016-05-04 | THR | A:97 | A:95 | 91.0 | 0.65 | -69.9 | -24.8 | 91.0 | 0.65 | 0.0 | |||||||
| 1wyw | 2 | P63165 | 100.0 | 2e-68 |
X-RAY |
2005-06-21 | THR | B:95 | B:95 | 128.0 | 0.914 | S | -59.4 | 160.6 | 128.0 | 0.914 | 0.0 | ||||||
| 1y8r | 3 | P63165 | 100.0 | 2e-68 |
X-RAY |
2005-01-25 | THR | C:95 | C:95 | 125.0 | 0.893 | -118.4 | -1.6 | 39.0 | 0.279 | 0.614 |
B:Q9UBT2:0.614 |
MG ATP HOH |
7.253 6.508 3.612 |
O O N |
MG O2A O |
||
| THR | F:95 | F:95 | 131.0 | 0.936 | -107.8 | 10.1 | NA | NA | NA | ||||||||||||||
| 2mw5 | 1 | P63165 | 100.0 | 2e-68 |
NMR |
2014-12-03 | THR | A:95 | A:98 | 141.0 | 1.0 | T | -128.8 | 19.2 | 141.0 | 1.0 | 0.0 | ||||||
| 2pe6 | 2 | P63165 | 100.0 | 2e-68 |
X-RAY |
2007-04-17 | THR | B:95 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 2kqs | 1 | P63165 | 100.0 | 3e-68 |
NMR |
2010-12-01 | THR | A:97 | A:95 | 116.0 | 0.829 | S | -55.1 | 146.4 | 116.0 | 0.829 | 0.0 | ||||||
| 2n1v | 1 | P63165 | 100.0 | 4e-68 |
NMR |
2016-04-20 | THR | A:109 | A:95 | 112.0 | 0.8 | -144.4 | 138.4 | 112.0 | 0.8 | 0.0 | |||||||
| 5b7a | 1 | P63165 | 100.0 | 4e-68 |
NMR |
2017-06-07 | THR | A:109 | A:95 | 81.0 | 0.579 | -112.3 | 22.5 | 81.0 | 0.579 | 0.0 | |||||||
| 5ghd | 1 | P63165 | 100.0 | 4e-68 |
NMR |
2017-06-07 | THR | A:109 | A:95 | 94.0 | 0.671 | -143.2 | 144.6 | 94.0 | 0.671 | 0.0 | |||||||
| 3kyc | 3 | P63165 | 98.97 | 2e-67 |
X-RAY |
2010-02-16 | CYS | C:95 | D:95 | 129.0 | 0.956 | -131.3 | 13.4 | 24.0 | 0.178 | 0.778 |
B:Q9UBT2:0.778 |
JZU HOH |
6.444 2.666 |
O N |
N18 O |
||
| 3rzw | 2 | P63165 | 98.97 | 2e-67 |
X-RAY |
2011-12-28 | THR | C:97 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | D:97 | D:95 | 115.0 | 0.821 | -109.8 | 161.1 | 115.0 | 0.821 | 0.0 |
HOH |
3.043 |
N |
O |
||||||||||
| 6j4i | 1 | P63165 | 98.97 | 2e-67 |
NMR |
2019-03-13 | THR | A:106 | A:95 | 87.0 | 0.621 | S | -76.9 | 88.4 | 87.0 | 0.621 | 0.0 | ||||||
| 3kyd | 3 | P63165 | 98.96 | 2e-66 |
X-RAY |
2010-02-16 | CYS | C:114 | D:95 | 139.0 | 1.0 | -100.5 | -1.2 | 39.0 | 0.289 | 0.711 |
B:Q9UBT2:0.741 |
VMX HOH |
4.227 3.515 |
O CA |
N12 O |
||
| 2iy0 | 2 | P63165 | 100.0 | 5e-57 |
X-RAY |
2006-08-07 | THR | B:76 | B:95 | 130.0 | 0.929 | -141.7 | 141.1 | 2.0 | 0.014 | 0.915 |
A:Q9P0U3:0.571 C:P46060:0.493 |
HOH |
7.437 |
N |
O |
||
| 2iy1 | 2 | P63165 | 100.0 | 6e-57 |
X-RAY |
2006-08-15 | THR | B:76 | B:90 | 128.0 | 0.914 | -124.0 | 156.7 | 54.0 | 0.386 | 0.528 |
A:Q9P0U3:0.529 |
HOH |
6.841 |
CB |
O |
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| THR | D:76 | D:90 | 128.0 | 0.914 | -124.9 | 160.8 | NA | NA | NA | ||||||||||||||
| 1tgz | 2 | P63165 | 100.0 | 3e-55 |
X-RAY |
2004-09-14 | THR | B:78 | B:95 | 128.0 | 0.914 | -153.1 | 154.9 | 54.0 | 0.386 | 0.528 |
A:Q9HC62:0.529 |
HOH |
5.949 |
CB |
O |
||
| 3uip | 2 | P63165 | 100.0 | 3e-55 |
X-RAY |
2011-12-28 | THR | B:78 | B:95 | 136.0 | 0.971 | -142.0 | 139.4 | 80.0 | 0.571 | 0.4 |
A:P63279:0.4 |
HOH |
3.076 |
O |
O |
||
| 1z5s | 2 | P63165 | 100.0 | 3e-55 |
X-RAY |
2005-06-07 | THR | B:80 | B:95 | 133.0 | 0.95 | -146.1 | 166.4 | 83.0 | 0.593 | 0.357 |
A:P63279:0.357 |
HOH |
7.197 |
CG2 |
O |
||
| 2io2 | 2 | P63165 | 100.0 | 3e-55 |
X-RAY |
2006-11-21 | THR | B:80 | B:95 | 126.0 | 0.9 | -151.5 | 139.3 | 23.0 | 0.164 | 0.736 |
A:Q9HC62:0.5 C:P46060:0.357 |
||||||
| 5elj | 2 | P63165 | 100.0 | 3e-55 |
X-RAY |
2016-11-16 | THR | B:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4wjn | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2014-12-31 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4wjo | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2014-12-31 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 4wjp | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2014-12-31 | THR | A:81 | A:95 | 148.0 | 1.0 | S | -76.3 | -32.2 | 148.0 | 1.0 | 0.0 |
HOH |
3.907 |
H |
O |
||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 4wjq | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2014-12-31 | THR | A:81 | A:95 | 133.0 | 0.95 | T | -137.8 | 82.6 | 133.0 | 0.95 | 0.0 |
HOH |
6.016 |
O |
O |
||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6uyo | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6uyp | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6uyq | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6uyr | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6uys | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6uyt | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6uyu | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | A:95 | 155.0 | 1.0 | S | -60.3 | 138.2 | 155.0 | 1.0 | 0.0 |
HOH |
2.747 |
HB |
O |
||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6uyv | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| 6uyx | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | C:95 | 149.0 | 1.0 | -70.8 | 120.9 | 149.0 | 1.0 | 0.0 |
HOH |
4.355 |
H |
O |
|||
| THR | C:81 | A:95 | 198.0 | 1.0 | -77.2 | 360.0 | NA | NA | NA | ||||||||||||||
| 6uyy | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | A:95 | 154.0 | 1.0 | T | -64.5 | 124.2 | 154.0 | 1.0 | 0.0 |
HOH |
2.795 |
OG1 |
O |
||
| 6uyz | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2019-11-27 | THR | A:81 | A:95 | 130.0 | 0.929 | -120.4 | 171.1 | 130.0 | 0.929 | 0.0 |
HOH |
2.212 |
H |
O |
|||
| THR | C:81 | C:95 | 190.0 | 1.0 | -116.4 | 360.0 | NA | NA | NA | ||||||||||||||
| 6v7p | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2020-04-08 | THR | A:81 | C:95 | 195.0 | 1.0 | -137.4 | 360.0 | 195.0 | 1.0 | 0.0 |
HOH |
6.801 |
H |
O |
|||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6v7q | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2020-04-01 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | C:81 | A:95 | 181.0 | 1.0 | -121.4 | 360.0 | NA | NA | NA | ||||||||||||||
| 6v7r | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2020-04-01 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 6v7s | 1 | P63165 | 98.77 | 8e-55 |
X-RAY |
2020-04-01 | THR | A:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
| THR | C:81 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
| 2g4d | 2 | P63165 | 100.0 | 7e-54 |
X-RAY |
2006-10-17 | THR | B:76 | B:95 | 122.0 | 0.871 | -136.4 | 161.0 | 51.0 | 0.364 | 0.507 |
A:Q9P0U3:0.507 |
HOH |
2.861 |
O |
O |
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| THR | D:76 | D:95 | 122.0 | 0.871 | -136.5 | 160.9 | NA | NA | NA | ||||||||||||||
| 2uyz | 2 | P63165 | 100.0 | 7e-54 |
X-RAY |
2007-06-12 | THR | B:77 | B:95 | 113.0 | 0.807 | -124.4 | 4.0 | 113.0 | 0.807 | 0.0 |
HOH |
3.786 |
CG2 |
O |
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| 2vrr | 2 | P63165 | 100.0 | 7e-54 |
X-RAY |
2008-08-19 | THR | B:77 | B:95 | 95.0 | 0.679 | T | -85.7 | 148.8 | 95.0 | 0.679 | 0.0 |
FMT HOH |
9.333 6.854 |
N O |
O1 O |
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| 2bf8 | 2 | P63165 | 100.0 | 3e-53 |
X-RAY |
2005-02-16 | THR | B:75 | B:95 | 117.0 | 0.836 | S | -44.0 | -39.0 | 83.0 | 0.593 | 0.243 |
A:P61085:0.243 |
HOH |
3.156 |
OG1 |
O |
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| 6k5t | 1 | P63165 | 100.0 | 3e-53 |
NMR |
2019-08-07 | THR | A:75 | A:95 | 99.0 | 0.707 | S | -66.7 | -39.0 | 99.0 | 0.707 | 0.0 | ||||||
| 5aek | 2 | P63165 | 97.44 | 2e-52 |
X-RAY |
2016-01-20 | THR | B:76 | B:95 | 121.0 | 0.864 | -129.5 | 158.2 | 47.0 | 0.336 | 0.528 |
A:Q9HC62:0.529 |
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| THR | D:76 | D:95 | 131.0 | 0.936 | -138.3 | 163.5 | NA | NA | NA | ||||||||||||||
| THR | F:76 | F:95 | 125.0 | 0.893 | -120.8 | 172.0 | NA | NA | NA | ||||||||||||||
| THR | H:76 | H:95 | 119.0 | 0.85 | -140.7 | 162.5 | NA | NA | NA | ||||||||||||||
| THR | J:76 | J:95 | 120.0 | 0.857 | -109.7 | 124.0 | NA | NA | NA | ||||||||||||||
| THR | L:76 | L:95 | 122.0 | 0.871 | -150.4 | 131.6 | NA | NA | NA | ||||||||||||||
| THR | N:76 | N:95 | 131.0 | 0.936 | -141.9 | 154.8 | NA | NA | NA | ||||||||||||||
| THR | P:76 | P:95 | 124.0 | 0.886 | -123.9 | 127.8 | NA | NA | NA | ||||||||||||||
| THR | R:76 | R:95 | 122.0 | 0.871 | -124.4 | 146.0 | NA | NA | NA | ||||||||||||||
| THR | T:76 | T:95 | 126.0 | 0.9 | -138.1 | 153.0 | NA | NA | NA | ||||||||||||||
| THR | V:76 | V:95 | 123.0 | 0.879 | -127.9 | 166.8 | NA | NA | NA | ||||||||||||||
| THR | X:76 | X:95 | 130.0 | 0.929 | -120.2 | 168.2 | NA | NA | NA | ||||||||||||||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p63165-f1 | 1 | P63165 | 100.0 | 4e-72 | THR | A:95 | A:95 | 122.0 | 0.871 | -72.2 | 95.3 | ||
| af-g2xkq0-f1 | 1 | G2XKQ0 | 88.12 | 1e-60 | ILE | A:95 | A:95 | 135.0 | 0.771 | -71.1 | 95.2 | ||