Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735326 . C A CCDS2362.1:NM_005214.4:c.127Cct>Act_NP_005205.2:p.43P>T Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 PRO A:8 A:8 52.0 0.359 -60.3 143.9 52.0 0.359 0.0 NAG
GOL
HOH
 9.443
8.479
3.344
 CG
C
CA
 C8
C3
O
PRO B:8 B:8 42.0 0.29 -54.9 149.2 42.0 0.29 0.0 NAG
HOH
 9.412
3.474
 CG
O
 O6
O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 PRO C:9 C:43 50.0 0.345 -55.5 148.7 NA NA NA
PRO F:9 F:43 49.0 0.338 -59.6 150.9 NA NA NA
PRO I:9 I:43 50.0 0.345 -57.6 150.3 NA NA NA
PRO L:9 L:43 47.0 0.324 -58.2 149.4 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 PRO C:8 C:8 39.0 0.269 -49.3 140.1 39.0 0.269 0.0
PRO D:8 D:8 35.0 0.241 -62.6 141.2 35.0 0.241 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 PRO C:8 Y:8 51.0 0.352 -66.7 153.7 51.0 0.352 0.0 HOH
 3.617
 CG
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 PRO E:8 c:8 53.0 0.366 -63.6 152.7 NA NA NA
PRO F:8 C:8 47.0 0.324 -65.5 151.1 47.0 0.324 0.0 HOH
 3.403
 CG
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 PRO C:8 C:8 44.0 0.303 -56.7 142.4 44.0 0.303 0.0 NAG
NAG
 9.046
9.011
 CD
C
 C8
O7
PRO D:8 D:8 54.0 0.372 -48.2 132.2 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 PRO A:9 D:8 59.0 0.407 -61.1 136.3 50.0 0.345 0.062 A:P16410:0.062
 HOH
 3.591
 CB
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 PRO A:7 A:6 45.0 0.31 -69.9 136.2 45.0 0.31 0.0 NAG
 6.904
 HG3
 H82
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 PRO B:7 A:8 34.0 0.234 E -66.3 133.8 34.0 0.234 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 PRO A:6 C:8 52.0 0.359 -56.2 140.0 52.0 0.359 0.0 HOH
 3.471
 CA
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 PRO A:6 A:8 44.0 0.303 -51.0 145.0 44.0 0.303 0.0 NAG
 6.836
 HG3
 H81
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 PRO A:7 A:8 42.0 0.29 -52.8 140.3 NA NA NA
PRO C:7 C:8 40.0 0.276 -53.1 140.2 NA NA NA
PRO E:7 E:8 43.0 0.297 -50.9 142.7 NA NA NA
PRO G:7 G:8 43.0 0.297 -51.9 141.5 43.0 0.297 0.0 NAG
NAG
 8.296
7.018
 CG
C
 C8
O7
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 PRO A:8 A:8 54.0 0.372 -60.3 156.7 47.0 0.324 0.048 G:P16410:0.048
 HOH
 3.536
 O
 O
PRO C:8 C:8 50.0 0.345 -71.4 148.6 NA NA NA
PRO E:8 E:8 50.0 0.345 -59.5 147.9 NA NA NA
PRO G:8 G:8 60.0 0.414 -62.7 143.8 60.0 0.414 0.0
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 PRO E:7 c:8 55.0 0.379 -55.0 157.0 NA NA NA
PRO F:7 C:8 47.0 0.324 -53.9 154.5 47.0 0.324 0.0
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 PRO E:7 C:8 50.0 0.345 -60.5 156.0 NA NA NA
PRO F:7 c:8 48.0 0.331 -61.5 154.4 48.0 0.331 0.0
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 PRO A:13 A:41 45.0 0.31 -64.7 141.4 45.0 0.31 0.0 HOH
 3.704
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 PRO A:43 A:43 47.0 0.324 -64.7 143.6