Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735350 . C A CCDS2362.1:NM_005214.4:c.151Cga>Aga_NP_005205.2:p.51R>R Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 ARG A:16 A:16 199.0 0.884 T -96.2 1.9 179.0 0.796 0.088 B:P16410:0.089
 NAG
HOH
 9.604
2.709
 NH1
O
 C6
O
ARG B:16 B:16 215.0 0.956 T -83.1 11.5 173.0 0.769 0.187 A:P16410:0.187
 HOH
 2.503
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 ARG C:17 C:51 206.0 0.916 S -61.3 -36.1 NA NA NA
ARG F:17 F:51 203.0 0.902 S -65.2 -38.4 NA NA NA
ARG I:17 I:51 205.0 0.911 S -63.6 -38.7 NA NA NA
ARG L:17 L:51 206.0 0.916 S -69.0 -40.4 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 ARG C:16 C:16 186.0 0.827 T -96.5 -13.0 186.0 0.827 0.0
ARG D:16 D:16 190.0 0.844 T -98.0 -13.6 190.0 0.844 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 ARG C:16 Y:16 217.0 0.964 T -86.8 4.6 217.0 0.964 0.0 HOH
 2.898
 O
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 ARG E:16 c:16 192.0 0.853 T -88.0 6.4 NA NA NA
ARG F:16 C:16 191.0 0.849 T -71.2 -6.2 191.0 0.849 0.0 HOH
 2.641
 O
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 ARG C:16 C:16 71.0 NA S -62.9 -92.3 71.0 NA NA
ARG D:16 D:16 77.0 NA S -66.0 -65.9 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 ARG A:17 D:16 208.0 0.924 T -78.3 -8.0 208.0 0.924 0.0 HOH
 3.745
 CB
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 ARG A:15 A:14 195.0 0.867 T -61.0 -29.6 195.0 0.867 0.0 NAG
BMA
 6.978
6.758
 HH21
HH21
 HO3
H61
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 ARG B:15 NA:NA DO NA DO DO DO NA NA NA
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 ARG A:14 C:16 198.0 0.88 T -92.1 10.1 191.0 0.849 0.031 A:P16410:0.031
 HOH
 2.699
 NH1
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 ARG A:14 A:16 207.0 0.92 T -59.8 -35.9 207.0 0.92 0.0 NAG
 8.226
 HH12
 H62
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 ARG A:15 A:16 218.0 0.969 S -64.4 -36.4 NA NA NA
ARG C:15 C:16 217.0 0.964 S -66.1 -33.4 NA NA NA
ARG E:15 E:16 219.0 0.973 S -63.7 -35.3 NA NA NA
ARG G:15 G:16 216.0 0.96 S -66.6 -30.0 216.0 0.96 0.0
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 ARG A:16 A:16 189.0 0.84 T -64.5 -16.5 189.0 0.84 0.0 HOH
 4.142
 CB
 O
ARG C:16 C:16 193.0 0.858 T -66.0 -13.7 NA NA NA
ARG E:16 E:16 193.0 0.858 S 61.8 32.1 NA NA NA
ARG G:16 G:16 208.0 0.924 T -80.4 2.2 208.0 0.924 0.0 HOH
 3.595
 O
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 ARG E:15 c:16 78.0 NA T -82.3 -3.2 NA NA NA
ARG F:15 C:16 109.0 NA S -73.2 -42.8 109.0 NA NA
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 ARG E:15 C:16 210.0 0.933 T -87.9 13.8 NA NA NA
ARG F:15 c:16 196.0 0.871 T -90.2 15.0 196.0 0.871 0.0
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 ARG A:21 A:49 213.0 0.947 T -89.2 -1.9 213.0 0.947 0.0 HOH
 2.824
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 ARG A:51 A:51 211.0 0.938 T -94.3 6.6