Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735422 . C A CCDS2362.1:NM_005214.4:c.223Cgg>Agg_NP_005205.2:p.75R>R Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 ARG A:40 A:40 65.0 0.289 E -91.1 128.1 65.0 0.289 0.0 HOH
 2.931
 O
 O
ARG B:40 B:40 65.0 0.289 E -105.5 123.0 65.0 0.289 0.0 HOH
 4.161
 NH1
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 ARG C:41 C:75 57.0 0.253 E -101.4 113.1 NA NA NA
ARG F:41 F:75 57.0 0.253 E -96.8 117.1 NA NA NA
ARG I:41 I:75 56.0 0.249 E -100.8 120.6 NA NA NA
ARG L:41 L:75 57.0 0.253 E -101.1 117.5 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 ARG C:40 C:40 72.0 0.32 -177.7 124.4 72.0 0.32 0.0
ARG D:40 D:40 85.0 0.378 -169.3 118.9 85.0 0.378 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 ARG C:40 Y:40 42.0 0.187 E -109.6 125.4 42.0 0.187 0.0 HOH
 2.769
 NH2
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 ARG E:40 c:40 44.0 0.196 E -112.7 123.0 NA NA NA
ARG F:40 C:40 51.0 0.227 E -111.0 122.8 51.0 0.227 0.0 HOH
 2.715
 O
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 ARG C:40 C:40 55.0 0.244 E -110.7 115.8 55.0 0.244 0.0
ARG D:40 D:40 49.0 0.218 E -137.1 104.1 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 ARG A:41 D:40 48.0 0.213 E -115.4 134.9 48.0 0.213 0.0 HOH
 2.998
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 ARG A:39 A:38 96.0 0.427 E -111.3 124.0 96.0 0.427 0.0 NAG
 9.724
 N
 H82
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 ARG B:39 A:40 43.0 0.191 E -145.9 120.8 43.0 0.191 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 ARG A:38 C:40 50.0 0.222 E -104.7 120.2 50.0 0.222 0.0 HOH
 2.740
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 ARG A:38 A:40 47.0 0.209 E -110.3 118.4 47.0 0.209 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 ARG A:39 A:40 53.0 0.236 E -90.8 114.5 NA NA NA
ARG C:39 C:40 52.0 0.231 E -94.0 114.4 NA NA NA
ARG E:39 E:40 48.0 0.213 E -93.7 113.2 NA NA NA
ARG G:39 G:40 50.0 0.222 E -90.3 117.4 13.0 0.058 0.164 H:None:0.164
 HOH
 9.646
 CB
 O
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 ARG A:40 A:40 56.0 0.249 E -107.0 127.4 56.0 0.249 0.0
ARG C:40 C:40 65.0 0.289 E -106.3 108.3 NA NA NA
ARG E:40 E:40 72.0 0.32 E -83.8 116.0 NA NA NA
ARG G:40 G:40 58.0 0.258 E -98.6 126.2 58.0 0.258 0.0
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 ARG E:39 c:40 60.0 0.267 E -121.1 125.5 NA NA NA
ARG F:39 C:40 54.0 0.24 E -120.9 125.9 54.0 0.24 0.0
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 ARG E:39 C:40 48.0 0.213 E -113.6 122.1 NA NA NA
ARG F:39 c:40 77.0 0.342 E -112.7 120.9 77.0 0.342 0.0
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 ARG A:45 A:73 80.0 0.356 E -88.5 130.6 80.0 0.356 0.0 HOH
 4.584
 CG
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 ARG A:75 A:75 48.0 0.213 E -100.1 128.4