Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735425 . C A CCDS2362.1:NM_005214.4:c.226Cag>Aag_NP_005205.2:p.76Q>K Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 GLN A:41 A:41 64.0 0.356 E -104.1 112.5 64.0 0.356 0.0 GOL
HOH
 9.152
2.276
 OE1
O
 O1
O
GLN B:41 B:41 72.0 0.4 E -101.2 123.1 72.0 0.4 0.0 HOH
 2.744
 NE2
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 GLN C:42 C:76 53.0 0.294 E -118.5 94.5 NA NA NA
GLN F:42 F:76 51.0 0.283 E -119.8 95.9 NA NA NA
GLN I:42 I:76 50.0 0.278 -123.7 92.5 NA NA NA
GLN L:42 L:76 56.0 0.311 E -121.4 92.9 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 GLN C:41 C:41 66.0 0.367 B -107.6 133.0 66.0 0.367 0.0
GLN D:41 D:41 130.0 0.722 -100.4 360.0 130.0 0.722 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 GLN C:41 Y:41 77.0 0.428 E -109.0 125.6 20.0 0.111 0.317 B:None:0.317
 HOH
 3.677
 CG
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 GLN E:41 c:41 84.0 0.467 E -102.5 125.6 NA NA NA
GLN F:41 C:41 64.0 0.356 E -100.2 122.7 45.0 0.25 0.106 A:None:0.089
B:None:0.044
 HOH
 2.581
 O
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 GLN C:41 C:41 75.0 0.417 E -98.4 141.6 75.0 0.417 0.0 NAG
 8.795
 NE2
 O6
GLN D:41 D:41 79.0 0.439 E -91.8 138.1 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 GLN A:42 D:41 81.0 0.45 E -117.4 123.8 81.0 0.45 0.0 HOH
 2.602
 NE2
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 GLN A:40 A:39 112.0 0.622 E -96.3 140.0 112.0 0.622 0.0 NAG
NAG
 6.101
9.857
 HE21
HE21
 O7
HO6
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 GLN B:40 A:41 103.0 0.572 E -87.9 120.7 26.0 0.144 0.428 A:None:0.428
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 GLN A:39 C:41 81.0 0.45 E -108.3 124.6 81.0 0.45 0.0 HOH
 2.811
 OE1
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 GLN A:39 A:41 84.0 0.467 E -93.8 104.7 84.0 0.467 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 GLN A:40 A:41 87.0 0.483 E -106.1 121.4 NA NA NA
GLN C:40 C:41 86.0 0.478 E -105.0 124.0 NA NA NA
GLN E:40 E:41 87.0 0.483 E -103.5 122.5 NA NA NA
GLN G:40 G:41 88.0 0.489 E -108.7 122.8 88.0 0.489 0.0
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 GLN A:41 A:41 98.0 0.544 E -74.8 93.5 39.0 0.217 0.327 H:None:0.194
G:P16410:0.189
GLN C:41 C:41 74.0 0.411 E -86.7 127.3 NA NA NA
GLN E:41 E:41 42.0 0.233 E -118.6 108.5 NA NA NA
GLN G:41 G:41 68.0 0.378 E -107.5 101.4 52.0 0.289 0.089 A:P16410:0.089
 HOH
 6.361
 OE1
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 GLN E:40 c:41 85.0 0.472 E -100.5 127.7 NA NA NA
GLN F:40 C:41 80.0 0.444 E -105.7 151.1 61.0 0.339 0.105 B:None:0.083
A:None:0.039
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 GLN E:40 C:41 81.0 0.45 E -110.2 117.3 NA NA NA
GLN F:40 c:41 73.0 0.406 E -109.9 116.8 44.0 0.244 0.162 B:None:0.122
A:None:0.072
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 GLU A:46 A:74 56.0 0.295 E -128.9 127.2 56.0 0.295 0.0 HOH
 2.718
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 GLN A:76 A:76 79.0 0.439 E -105.5 120.1