Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735437 . C A CCDS2362.1:NM_005214.4:c.238Cag>Aag_NP_005205.2:p.80Q>K Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 GLN A:45 A:45 121.0 0.672 E -67.8 122.6 121.0 0.672 0.0 HOH
 3.280
 O
 O
GLN B:45 B:45 109.0 0.606 -105.1 158.2 109.0 0.606 0.0 HOH
 3.593
 CB
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 GLN C:46 C:80 111.0 0.617 E -86.3 149.5 NA NA NA
GLN F:46 F:80 100.0 0.556 E -101.9 157.5 NA NA NA
GLN I:46 I:80 107.0 0.594 -76.3 145.3 NA NA NA
GLN L:46 L:80 109.0 0.606 E -88.5 146.2 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 GLN C:45 C:45 141.0 0.783 -63.5 108.8 141.0 0.783 0.0
GLN D:45 D:45 199.0 1.0 360.0 -152.6 199.0 1.0 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 GLN C:45 Y:45 88.0 0.489 E -142.5 146.5 84.0 0.467 0.022 B:None:0.022
 HOH
 2.198
 NE2
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 GLN E:45 c:45 131.0 0.728 E -85.0 124.7 NA NA NA
GLN F:45 C:45 120.0 0.667 E -84.1 119.3 120.0 0.667 0.0 HOH
 3.303
 O
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 GLN C:45 C:45 133.0 0.739 -106.7 111.5 133.0 0.739 0.0
GLN D:45 D:45 62.0 NA E -69.0 125.3 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 GLN A:46 D:45 129.0 0.717 E -80.6 129.5 129.0 0.717 0.0 HOH
 3.252
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 GLN A:44 A:43 140.0 0.778 -165.1 169.5 140.0 0.778 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 GLN B:44 A:45 127.0 0.706 -162.7 124.1 96.0 0.533 0.173 A:None:0.172
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 GLN A:43 C:45 122.0 0.678 E -107.0 141.7 122.0 0.678 0.0 HOH
 3.498
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 GLN A:43 A:45 130.0 0.722 E -169.4 141.9 130.0 0.722 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 GLN A:44 A:45 119.0 0.661 -154.0 141.1 NA NA NA
GLN C:44 C:45 118.0 0.656 -153.6 140.2 NA NA NA
GLN E:44 E:45 118.0 0.656 -150.9 144.9 NA NA NA
GLN G:44 G:45 120.0 0.667 -150.3 143.6 56.0 0.311 0.356 H:None:0.356
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 GLN A:45 A:45 147.0 0.817 S -139.5 -177.9 66.0 0.367 0.45 H:None:0.45
 HOH
 5.029
 NE2
 O
GLN C:45 C:45 134.0 0.744 E -122.0 163.2 NA NA NA
GLN E:45 E:45 132.0 0.733 E -87.4 121.7 NA NA NA
GLN G:45 G:45 121.0 0.672 E -79.6 142.7 43.0 0.239 0.433 A:P16410:0.433
 HOH
 7.297
 N
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 GLN E:44 c:45 160.0 0.889 E -117.7 -173.2 NA NA NA
GLN F:44 C:45 141.0 0.783 E -70.9 163.4 141.0 0.783 0.0
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 GLN E:44 C:45 132.0 0.733 E -82.7 144.3 NA NA NA
GLN F:44 c:45 150.0 0.833 E -88.3 144.5 137.0 0.761 0.072 B:None:0.072
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 GLN A:50 A:78 137.0 0.761 E -81.5 117.0 137.0 0.761 0.0 HOH
 2.766
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 GLN A:80 A:80 134.0 0.744 E -86.4 133.1