Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735444 . C A CCDS2362.1:NM_005214.4:c.245aCt>aAt_NP_005205.2:p.82T>N Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 THR A:47 A:47 87.0 0.621 E -140.3 137.1 87.0 0.621 0.0 HOH
 2.914
 OG1
 O
THR B:47 B:47 88.0 0.629 E -138.3 147.8 88.0 0.629 0.0 HOH
 3.473
 CG2
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 THR C:48 C:82 75.0 0.536 E -118.9 129.4 NA NA NA
THR F:48 F:82 72.0 0.514 E -125.0 131.2 NA NA NA
THR I:48 I:82 72.0 0.514 E -129.5 127.0 NA NA NA
THR L:48 L:82 75.0 0.536 E -124.5 132.6 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 THR C:47 C:47 84.0 0.6 -135.5 163.2 84.0 0.6 0.0
THR D:47 D:47 82.0 0.586 -133.0 164.7 82.0 0.586 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 THR C:47 Y:47 58.0 0.414 E -131.7 157.2 58.0 0.414 0.0 HOH
 2.821
 OG1
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 THR E:47 c:47 65.0 0.464 E -119.9 149.5 NA NA NA
THR F:47 C:47 62.0 0.443 E -122.5 151.4 56.0 0.4 0.043 A:None:0.043
 HOH
 3.022
 OG1
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 THR C:47 C:47 82.0 0.586 -151.6 127.7 82.0 0.586 0.0
THR D:47 D:47 81.0 0.579 E -137.4 147.8 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 THR A:48 D:47 84.0 0.6 E -120.1 149.5 84.0 0.6 0.0 HOH
 3.128
 OG1
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 THR A:46 A:45 69.0 0.493 E -130.0 160.6 69.0 0.493 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 THR B:46 A:47 57.0 0.407 E -143.7 139.9 52.0 0.371 0.036 A:None:0.036
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 THR A:45 C:47 75.0 0.536 E -132.8 151.1 57.0 0.407 0.129 B:None:0.129
 HOH
 2.891
 OG1
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 THR A:45 A:47 74.0 0.529 E -153.7 142.6 74.0 0.529 0.0
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 THR A:46 A:47 69.0 0.493 E -132.9 113.9 NA NA NA
THR C:46 C:47 67.0 0.479 E -131.1 116.4 NA NA NA
THR E:46 E:47 64.0 0.457 E -132.7 114.3 NA NA NA
THR G:46 G:47 63.0 0.45 E -133.3 115.8 2.0 0.014 0.436 H:None:0.436
 NA
HOH
 9.989
8.167
 C
CG2
 NA
O
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 THR A:47 A:47 74.0 0.529 E -110.8 130.7 74.0 0.529 0.0
THR C:47 C:47 70.0 0.5 E -117.2 140.3 NA NA NA
THR E:47 E:47 76.0 0.543 E -131.9 122.7 NA NA NA
THR G:47 G:47 81.0 0.579 E -128.7 122.9 31.0 0.221 0.358 A:P16410:0.357
 HOH
 8.791
 CG2
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 THR E:46 c:47 88.0 0.629 E -116.1 148.8 NA NA NA
THR F:46 C:47 70.0 0.5 E -135.2 137.5 69.0 0.493 0.007 B:None:0.007
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 THR E:46 C:47 65.0 0.464 E -129.1 156.4 NA NA NA
THR F:46 c:47 84.0 0.6 E -125.3 155.7 79.0 0.564 0.036 A:None:0.036
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 THR A:52 A:80 78.0 0.557 E -137.8 135.2 78.0 0.557 0.0 HOH
 5.398
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 THR A:82 A:82 51.0 0.364 E -119.5 138.2