Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735548 . C A CCDS2362.1:NM_005214.4:c.349Caa>Aaa_NP_005205.2:p.117Q>K Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 GLN A:82 A:82 88.0 0.489 -118.6 170.4 88.0 0.489 0.0 NAG
HOH
 9.353
2.721
 NE2
NE2
 C6
O
GLN B:82 B:82 61.0 0.339 -119.1 167.0 61.0 0.339 0.0 HOH
 3.685
 CB
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 GLN C:83 C:117 95.0 0.528 -92.5 -169.4 NA NA NA
GLN F:83 F:117 91.0 0.506 -94.6 -171.1 NA NA NA
GLN I:83 I:117 91.0 0.506 -94.2 -171.5 NA NA NA
GLN L:83 L:117 92.0 0.511 -91.2 -171.2 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 GLN C:82 C:82 86.0 0.478 -115.9 177.7 86.0 0.478 0.0
GLN D:82 D:82 91.0 0.506 -112.8 176.0 91.0 0.506 0.0
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 GLN C:82 Y:82 94.0 0.522 -109.4 171.4 94.0 0.522 0.0 HOH
 3.222
 NE2
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 GLN E:82 c:82 93.0 0.517 -109.9 170.7 NA NA NA
GLN F:82 C:82 83.0 0.461 -113.1 167.8 83.0 0.461 0.0 HOH
 4.012
 C
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 GLN C:82 C:82 97.0 0.539 -138.1 169.0 97.0 0.539 0.0 NAG
 7.944
 OE1
 O6
GLN D:82 D:82 99.0 0.55 -170.5 166.5 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 GLN A:83 D:82 95.0 0.528 -116.4 166.6 95.0 0.528 0.0 HOH
 2.666
 NE2
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 GLN A:81 A:82 105.0 0.583 E -124.5 120.9 105.0 0.583 0.0 NAG
NAG
BMA
FUC
 7.140
3.451
6.201
5.964
 HE21
HE22
HE22
HE21
 H3
HO3
O5
H62
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 GLN B:81 A:82 120.0 0.667 -117.4 160.6 120.0 0.667 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 GLN A:80 C:82 92.0 0.511 -118.2 179.7 92.0 0.511 0.0 HOH
 3.358
 OE1
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 GLN A:80 A:82 128.0 0.711 E -117.1 159.8 128.0 0.711 0.0 NAG
 5.638
 HE21
 H61
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 GLN A:81 A:82 89.0 0.494 -117.4 161.3 NA NA NA
GLN C:81 C:82 86.0 0.478 -116.3 163.6 NA NA NA
GLN E:81 E:82 89.0 0.494 -118.2 158.2 NA NA NA
GLN G:81 G:82 86.0 0.478 -118.5 157.7 86.0 0.478 0.0 NAG
FUC
HOH
 7.162
5.734
7.465
 NE2
NE2
O
 C6
C6
O
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 GLN A:82 A:82 94.0 0.522 -130.2 165.6 94.0 0.522 0.0 HOH
 2.997
 NE2
 O
GLN C:82 C:82 96.0 0.533 -119.5 169.9 NA NA NA
GLN E:82 E:82 80.0 0.444 E -116.4 134.8 NA NA NA
GLN G:82 G:82 83.0 0.461 -115.9 163.9 83.0 0.461 0.0 HOH
 5.481
 C
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 GLN E:81 c:82 92.0 0.511 -121.9 168.5 NA NA NA
GLN F:81 C:82 104.0 0.578 -129.7 -173.5 104.0 0.578 0.0
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 GLN E:81 C:82 77.0 0.428 -118.4 167.7 NA NA NA
GLN F:81 c:82 114.0 0.633 -113.6 166.2 114.0 0.633 0.0
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 GLN A:87 A:115 69.0 0.383 -118.3 173.4 69.0 0.383 0.0 HOH
 3.703
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 GLN A:117 A:117 90.0 0.5 -106.8 172.7