Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735606 . C A CCDS2362.1:NM_005214.4:c.407cCa>cAa_NP_005205.2:p.136P>Q Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 PRO A:101 A:101 60.0 0.414 S -53.1 152.7 60.0 0.414 0.0 GOL
HOH
 8.697
2.881
 O
O
 C3
O
PRO B:101 B:101 51.0 0.352 S -82.2 172.2 51.0 0.352 0.0 HOH
 4.093
 CB
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 PRO C:102 C:136 34.0 0.234 S -86.3 165.7 NA NA NA
PRO F:102 F:136 31.0 0.214 S -87.4 164.3 NA NA NA
PRO I:102 I:136 34.0 0.234 S -86.6 167.2 NA NA NA
PRO L:102 L:136 32.0 0.221 S -83.6 167.5 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 PRO C:101 C:101 25.0 0.172 S -83.8 165.0 25.0 0.172 0.0
PRO D:101 D:101 39.0 0.269 S -85.3 153.3 22.0 0.152 0.117 B:P42081:0.117
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 PRO C:101 Y:101 59.0 0.407 S -63.8 161.7 59.0 0.407 0.0 HOH
 2.886
 O
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 PRO E:101 c:101 49.0 0.338 S -68.6 159.7 NA NA NA
PRO F:101 C:101 54.0 0.372 S -72.0 161.9 54.0 0.372 0.0 HOH
 3.430
 O
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 PRO C:101 C:101 55.0 0.379 S -75.9 164.5 55.0 0.379 0.0
PRO D:101 D:101 52.0 0.359 S -70.5 154.8 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 PRO A:102 D:101 84.0 0.579 -73.6 155.8 79.0 0.545 0.034 A:P16410:0.034
 HOH
 2.584
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 PRO A:100 A:101 40.0 0.276 S -80.8 137.2 40.0 0.276 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 PRO B:100 A:101 45.0 0.31 S -73.3 179.0 45.0 0.31 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 PRO A:99 C:101 58.0 0.4 S -87.1 176.6 9.0 0.062 0.338 B:None:0.338
 HOH
 3.214
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 PRO A:99 A:101 52.0 0.359 S -82.4 162.4 26.0 0.179 0.18 B:None:0.179
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 PRO A:100 A:101 48.0 0.331 S -78.8 174.2 NA NA NA
PRO C:100 C:101 50.0 0.345 S -78.5 173.9 NA NA NA
PRO E:100 E:101 48.0 0.331 S -78.5 172.2 NA NA NA
PRO G:100 G:101 45.0 0.31 S -79.2 172.0 45.0 0.31 0.0
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 PRO A:101 A:101 67.0 0.462 S -67.8 157.6 67.0 0.462 0.0 HOH
 9.662
 N
 O
PRO C:101 C:101 64.0 0.441 S -67.9 162.7 NA NA NA
PRO E:101 E:101 66.0 0.455 S -72.9 166.3 NA NA NA
PRO G:101 G:101 64.0 0.441 S -69.5 159.4 64.0 0.441 0.0
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 PRO E:100 c:101 49.0 0.338 S -69.9 165.7 NA NA NA
PRO F:100 C:101 53.0 0.366 S -74.4 164.8 53.0 0.366 0.0
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 PRO E:100 C:101 52.0 0.359 S -74.0 166.4 NA NA NA
PRO F:100 c:101 51.0 0.352 S -73.3 168.2 51.0 0.352 0.0
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 PRO A:106 A:134 33.0 0.228 S -81.8 166.9 33.0 0.228 0.0 HOH
 2.753
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 PRO A:136 A:136 57.0 0.393 S -72.4 160.1