Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735609 . C A CCDS2362.1:NM_005214.4:c.410cCg>cAg_NP_005205.2:p.137P>Q Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 PRO A:102 A:102 95.0 0.655 S -66.7 166.9 95.0 0.655 0.0 GOL
HOH
 8.395
2.864
 O
O
 C3
O
PRO B:102 B:102 101.0 0.697 S -53.6 155.8 101.0 0.697 0.0 HOH
 2.524
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 PRO C:103 C:137 102.0 0.703 S -48.4 148.4 NA NA NA
PRO F:103 F:137 101.0 0.697 S -49.8 147.6 NA NA NA
PRO I:103 I:137 104.0 0.717 S -52.7 150.2 NA NA NA
PRO L:103 L:137 101.0 0.697 S -50.0 148.1 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 PRO C:102 C:102 94.0 0.648 S -60.4 155.9 94.0 0.648 0.0
PRO D:102 D:102 100.0 0.69 S -58.0 167.1 7.0 0.048 0.642 B:P42081:0.641
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 PRO C:102 Y:102 93.0 0.641 S -61.7 161.3 62.0 0.428 0.213 B:None:0.207
A:None:0.021
 HOH
 2.892
 O
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 PRO E:102 c:102 98.0 0.676 S -59.0 156.6 NA NA NA
PRO F:102 C:102 101.0 0.697 S -58.6 155.5 82.0 0.566 0.131 A:None:0.131
B:None:0.021
 HOH
 2.512
 O
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 PRO C:102 C:102 94.0 0.648 S -69.5 169.9 23.0 0.159 0.489 A:P33681:0.49
PRO D:102 D:102 94.0 0.648 S -68.2 169.6 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 PRO A:103 D:102 117.0 0.807 -68.5 126.9 80.0 0.552 0.255 A:P16410:0.255
 HOH
 3.487
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 PRO A:101 A:102 123.0 0.848 T -90.0 143.8 123.0 0.848 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 PRO B:101 A:102 103.0 0.71 S -59.8 160.3 103.0 0.71 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 PRO A:100 C:102 108.0 0.745 S -54.4 156.0 17.0 0.117 0.628 B:None:0.628
 HOH
 2.849
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 PRO A:100 A:102 96.0 0.662 S -67.6 162.3 12.0 0.083 0.579 B:None:0.579
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 PRO A:101 A:102 105.0 0.724 S -59.3 156.0 NA NA NA
PRO C:101 C:102 108.0 0.745 S -60.3 155.9 NA NA NA
PRO E:101 E:102 104.0 0.717 S -57.7 156.6 NA NA NA
PRO G:101 G:102 101.0 0.697 S -57.3 156.9 64.0 0.441 0.256 A:P16410:0.255
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 PRO A:102 A:102 102.0 0.703 S -60.0 160.7 102.0 0.703 0.0 HOH
 9.665
 CD
 O
PRO C:102 C:102 101.0 0.697 S -58.4 157.0 NA NA NA
PRO E:102 E:102 106.0 0.731 S -61.6 159.5 NA NA NA
PRO G:102 G:102 99.0 0.683 S -61.0 158.5 99.0 0.683 0.0 HOH
 9.881
 CD
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 PRO E:101 c:102 105.0 0.724 S -56.5 155.0 NA NA NA
PRO F:101 C:102 99.0 0.683 S -54.2 162.2 78.0 0.538 0.145 B:None:0.145
A:None:0.014
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 PRO E:101 C:102 103.0 0.71 S -63.6 155.7 NA NA NA
PRO F:101 c:102 100.0 0.69 S -62.8 154.2 75.0 0.517 0.173 B:None:0.021
A:None:0.159
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 PRO A:107 A:135 98.0 0.676 S -57.3 154.0 98.0 0.676 0.0 HOH
 3.640
 C
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 PRO A:137 A:137 102.0 0.703 S -55.7 148.0