Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735611 . C A CCDS2362.1:NM_005214.4:c.412Cca>Aca_NP_005205.2:p.138P>T Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 PRO A:103 A:103 62.0 0.428 S -76.0 161.5 62.0 0.428 0.0 GOL
HOH
 6.750
2.984
 CD
O
 C3
O
PRO B:103 B:103 71.0 0.49 S -87.9 163.6 71.0 0.49 0.0 HOH
 4.528
 N
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 PRO C:104 C:138 78.0 0.538 S -90.5 164.4 NA NA NA
PRO F:104 F:138 77.0 0.531 S -89.5 161.5 NA NA NA
PRO I:104 I:138 77.0 0.531 S -87.1 169.2 NA NA NA
PRO L:104 L:138 76.0 0.524 S -90.3 160.0 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 PRO C:103 C:103 72.0 0.497 S -86.3 164.7 72.0 0.497 0.0
PRO D:103 D:103 83.0 0.572 S -80.6 160.5 30.0 0.207 0.365 B:P42081:0.366
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 PRO C:103 Y:103 85.0 0.586 S -79.0 156.7 55.0 0.379 0.207 B:None:0.007
A:None:0.207
 HOH
 2.844
 O
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 PRO E:103 c:103 81.0 0.559 S -73.5 154.0 NA NA NA
PRO F:103 C:103 81.0 0.559 S -72.9 153.3 57.0 0.393 0.166 A:None:0.007
B:None:0.166
 HOH
 3.306
 CD
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 PRO C:103 C:103 84.0 0.579 S -69.7 160.5 28.0 0.193 0.386 A:P33681:0.386
PRO D:103 D:103 90.0 0.621 S -57.6 164.6 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 PRO A:104 D:103 110.0 0.759 -62.5 146.3 37.0 0.255 0.504 A:P16410:0.503
 HOH
 2.724
 O
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 PRO A:102 A:103 120.0 0.828 T -114.4 64.7 120.0 0.828 0.0
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 PRO B:102 A:103 112.0 0.772 S -79.2 154.6 112.0 0.772 0.0
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 PRO A:101 C:103 109.0 0.752 S -87.2 146.6 24.0 0.166 0.586 B:None:0.586
 HOH
 2.775
 O
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 PRO A:101 A:103 87.0 0.6 S -73.6 157.4 15.0 0.103 0.497 B:None:0.428
C:None:0.166
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 PRO A:102 A:103 76.0 0.524 S -85.6 165.5 NA NA NA
PRO C:102 C:103 78.0 0.538 S -85.9 165.6 NA NA NA
PRO E:102 E:103 76.0 0.524 S -86.0 165.2 NA NA NA
PRO G:102 G:103 78.0 0.538 S -85.1 165.5 65.0 0.448 0.09 B:None:0.083
A:P16410:0.007
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 PRO A:103 A:103 86.0 0.593 S -71.7 155.3 86.0 0.593 0.0 HOH
 7.717
 C
 O
PRO C:103 C:103 50.0 0.345 S -80.8 158.4 NA NA NA
PRO E:103 E:103 86.0 0.593 S -89.0 167.5 NA NA NA
PRO G:103 G:103 78.0 0.538 S -81.0 170.6 78.0 0.538 0.0
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 PRO E:102 c:103 76.0 0.524 S -84.5 160.3 NA NA NA
PRO F:102 C:103 71.0 0.49 S -74.4 162.7 48.0 0.331 0.159 B:None:0.007
A:None:0.159
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 PRO E:102 C:103 75.0 0.517 S -80.3 157.2 NA NA NA
PRO F:102 c:103 73.0 0.503 S -79.2 160.2 49.0 0.338 0.165 B:None:0.166
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 PRO A:108 A:136 87.0 0.6 S -84.5 155.2 87.0 0.6 0.0 HOH
 2.692
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 PRO A:138 A:138 60.0 0.414 S -84.4 158.8