Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr2 204735615 . A C CCDS2362.1:NM_005214.4:c.416tAc>tCc_NP_005205.2:p.139Y>S Homo sapiens cytotoxic T-lymphocyte associated protein 4 (CTLA4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3osk 1 P16410 98.44 1e-90 X-RAY
 2010-12-08 TYR A:104 A:104 114.0 0.496 -73.9 131.8 114.0 0.496 0.0 GOL
HOH
 6.935
2.662
 O
OH
 O1
O
TYR B:104 B:104 125.0 0.543 -68.2 134.8 125.0 0.543 0.0 HOH
 4.192
 O
 O
5xj3 3 P16410 100.0 1e-90 X-RAY
 2018-04-25 TYR C:105 C:139 117.0 0.509 -67.8 136.4 NA NA NA
TYR F:105 F:139 115.0 0.5 -66.9 136.0 NA NA NA
TYR I:105 I:139 114.0 0.496 -74.5 138.6 NA NA NA
TYR L:105 L:139 116.0 0.504 -61.2 141.5 NA NA NA
1i85 2 P16410 100.0 2e-90 X-RAY
 2001-04-04 TYR C:104 C:104 111.0 0.483 -67.3 -168.7 111.0 0.483 0.0
TYR D:104 D:104 110.0 0.478 -67.2 -176.5 11.0 0.048 0.43 B:P42081:0.43
5ggv 3 P16410 100.0 2e-90 X-RAY
 2016-11-09 TYR C:104 Y:104 114.0 0.496 -65.6 142.2 0.0 0.0 0.496 B:None:0.296
A:None:0.309
 HOH
 3.710
 OH
 O
7elx 3 P16410 100.0 2e-90 X-RAY
 2021-06-30 TYR E:104 c:104 114.0 0.496 -64.4 137.6 NA NA NA
TYR F:104 C:104 110.0 0.478 -65.7 139.4 5.0 0.022 0.456 A:None:0.217
B:None:0.33
 HOH
 2.601
 OH
 O
1i8l 2 P16410 99.21 9e-90 X-RAY
 2001-04-04 TYR C:104 C:104 114.0 0.496 -86.8 135.3 1.0 0.004 0.492 A:P33681:0.491
TYR D:104 D:104 119.0 0.517 -95.0 144.6 NA NA NA
2x44 1 P16410 97.66 1e-89 X-RAY
 2010-04-07 TYR A:105 D:104 189.0 0.822 -148.3 123.1 72.0 0.313 0.509 A:P16410:0.509
 HOH
 3.706
 CB
 O
1ah1 1 P16410 100.0 1e-89 NMR
 1998-04-15 TYR A:103 A:104 96.0 0.417 48.1 111.8 96.0 0.417 0.0 NAG
 9.596
 OH
 H81
6rqm 2 P16410 100.0 1e-89 X-RAY
 2020-07-08 TYR B:103 A:104 126.0 0.548 -67.8 125.8 75.0 0.326 0.222 A:None:0.222
3bx7 1 P16410 100.0 5e-89 X-RAY
 2009-01-20 TYR A:102 C:104 120.0 0.522 -63.7 137.8 13.0 0.057 0.465 B:None:0.465
 HOH
 2.926
 N
 O
6xy2 1 P16410 100.0 6e-88 X-RAY
 2020-12-09 TYR A:102 A:104 121.0 0.526 -87.0 135.6 68.0 0.296 0.23 B:None:0.23
6rpj 1 P16410 100.0 2e-85 X-RAY
 2020-07-08 TYR A:103 A:104 120.0 0.522 -77.8 131.2 NA NA NA
TYR C:103 C:104 121.0 0.526 -77.0 132.0 NA NA NA
TYR E:103 E:104 122.0 0.53 -76.1 130.3 NA NA NA
TYR G:103 G:104 124.0 0.539 -76.0 132.3 19.0 0.083 0.456 B:None:0.148
A:P16410:0.413
7dv4 1 P16410 100.0 1e-83 X-RAY
 2022-01-12 TYR A:104 A:104 118.0 0.513 -73.2 136.9 72.0 0.313 0.2 B:None:0.183
H:None:0.03
 EDO
HOH
 6.805
4.521
 CE2
O
 O1
O
TYR C:104 C:104 110.0 0.478 -72.8 129.7 NA NA NA
TYR E:104 E:104 121.0 0.526 -68.3 122.3 NA NA NA
TYR G:104 G:104 126.0 0.548 -87.0 130.1 55.0 0.239 0.309 A:P16410:0.157
H:None:0.2
 HOH
 7.526
 OH
 O
5tru 3 P16410 100.0 2e-83 X-RAY
 2017-05-10 TYR E:103 c:104 107.0 0.465 -66.5 129.9 NA NA NA
TYR F:103 C:104 118.0 0.513 -65.9 134.4 4.0 0.017 0.496 B:None:0.243
A:None:0.33
6rp8 3 P16410 100.0 2e-83 X-RAY
 2020-07-08 TYR E:103 C:104 106.0 0.461 -67.6 137.2 NA NA NA
TYR F:103 c:104 117.0 0.509 -70.6 137.9 6.0 0.026 0.483 B:None:0.352
A:None:0.204
 HOH
 4.668
 OH
 O
4kkn 1 Q28090 80.65 3e-70 X-RAY
 2013-06-12 TYR A:109 A:137 128.0 0.557 -66.9 135.4 128.0 0.557 0.0 HOH
 2.485
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p16410-f1 1 P16410 100.0 2e-168 TYR A:139 A:139 79.0 0.343 -71.2 131.6